scholarly journals Impact of Iron Deficiency Anemia on Glycated Hemoglobin (HbA1c) Levels in Diabetics with Controlled Plasma Glucose Levels

2017 ◽  
Vol 4 (2) ◽  
pp. A148-A152 ◽  
Author(s):  
Lavanya Rajagopal ◽  
Sundaram Arunachalam ◽  
Shivashekar Ganapathy ◽  
Balaji Ramraj
Author(s):  
Dr. Suman Choudhary ◽  
Dr. Sukh Dev Choudhary ◽  
Dr. Himanshi Choudhary ◽  
Dr. Ronak Gandhi

Background: Iron deficiency anemia is the most common form of anemia in India. Hemoglobin A1c (HbA1c) is used in diabetic patients as an index of glycemic control reflecting glucose levels of the previous 3 months. Like blood sugar levels, HbA1c levels are also affected by the presence of variant hemoglobins, hemolytic anemias, nutritional anemias, uremia, pregnancy, and acute blood loss. Previous studies suggest that iron deficiency anemia (IDA) affects the levels of HbA1c. Methods: A prospective observational study on 50 iron deficiency patient cases and 50 healthy control. Exclusion and inclusion criteria were used to recruit cases from the wards and OPDs of the hospital. Appropriate descriptive statistics was used to analyse the data. Results: The HbA1C was significantly higher in the iron deficiency patients as compare to the control (5.88 ± 0.41 vs 5.03 ± 0.17, respectively, P < .05). Conclusion: Our results showed that iron deficiency was associated with higher proportions of HbA1c, which could cause problems in the diagnosis of uncontrolled diabetes mellitus in iron-deficient patients. Keywords: Non-Diabetic Patient, Glycosylated Haemoglobin, Iron Deficiency Anaemia.


2017 ◽  
Vol 36 ◽  
pp. S51-S52
Author(s):  
G. Kaner ◽  
N. Seremet Kurklu ◽  
G. Pamuk

2020 ◽  
Vol 4 (1) ◽  
pp. 10-16
Author(s):  
R.K. Bansal ◽  
Y.R. Yadav ◽  
H.S. Kulkarni ◽  
Sonam ◽  
S. Garg ◽  
...  

Background: Glycated hemoglobin A1c is a well-known indicator of glycemic control in diabetes patients. It comprises of 5% of total hemoglobin in non-diabetic patients as well. Iron Deficiency Anemia is most common cause of anemia, especially in this part of the world. So, we study the effects of Iron deficiency Anemia on HbA1c levels in non-diabetic adults to determine whether the HbA1c levels increase if any. Methods: A 100 non-diabetic adult patients with Iron Deficiency anemia admitted in various medicine wards and attending OPDs of J.L.N. Medical College and 100 healthy controls were enrolled after fulfilled inclusion and exclusion criteria. Detailed history of clinical examination and biochemical examination was performed including HbA1c. Results: Mean HbA1c level is more in iron deficient Anemic non-diabetic patients in comparison to non-Anemic non-diabetic patients. Mean HbA1c is 5.01 ± 0.41 in control group. While mean HbA1c level in case group is 6.11 ± 0.42. The difference is statistically significant (p value <.001). Conclusion: Iron deficiency Anemia is independent factor affecting HbA1c level in non diabetic patients & it should be interpreted carefully in all iron deficient anemic patients.  


2020 ◽  
Vol 27 (09) ◽  
pp. 1849-1854
Author(s):  
Muhammad Danish Qureshi ◽  
Saman Waqar ◽  
Muhammad Ihtesham Khan ◽  
Lubna Naseem

Objectives: To determine association of iron deficiency anemia on hba1c level in diabetic patients. Study Design: Cross Sectional Analytical study. Setting: Department of Pathology PIMS Hospital. Period: From June 2018 to December 2018 (6 months duration). Material & Methods: A total of 117 diagnosed cases of diabetes mellitus were included in the study. Pregnant women, patients with end-stage renal disease, hypothyroidism, +hemoglobinopathies, hemolytic anemia, chronic liver disease and malignancy, participants with poorly controlled diabetes, and patient from the northern areas were excluded from the study. Patients were divided according to their fasting plasma glucose (FPG) level. FPG of 126mg/dl was used as a cut-off point for dividing the study population into two groups, i.e controlled sugar level (FPG between 100 and 126 mg/d L) and well controlled sugar level (FPG less than 100 mg/d L). Variables such as Hemoglobin, serum ferritin, serum Hba1c level etc. Results: Mean age of study population in the present study was 56.97±7.29 years. Out of 117 cases, about 45(38.5%) cases were female and 72 (38.5%) were male. Male to female ratio was 1: 1.6.Mean FPG level was 103.3±7.6 in our study population. The mean hba1c levels in the sample was 6.42±0.70 %. Mean Hb levels were recorded as 11.5±2.7 and 10.9±3.03 g/dl, respectively in female and male. From a total of 117 cases, only 66 were identified as having iron deficiency anemia. Only 54 patients had plasma glucose greater than 100 mg/dl. Odds ratio for hba1c>6.5% in iron deficient was 3.90(p=0.001). Conclusion: Iron deficiency can cause elevated serum hba1c level. Health care providers, including physicians, must consider the iron status before prescribing diabetics treatment on the basis of serum hba1c level.


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