Regulation of mRNA Expression of MDR1, MRP1, MRP2 and MRP3 by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Rat Hepatocytes

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.21.297 ◽

2006 ◽

Vol 21 (4) ◽

pp. 297-307 ◽

Author(s):

Masuhiro Nishimura ◽

Akiko Koeda ◽

Emako Suzuki ◽

Yuichi Kawano ◽

Mitsuo Nakayama ◽

...

Keyword(s):

Mrna Expression ◽

Primary Cultures ◽

Rat Hepatocytes ◽

Microsomal Enzyme ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text

Effects of prototypical drug-metabolizing enzyme inducers on mRNA expression of housekeeping genes in primary cultures of human and rat hepatocytes

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2006.06.012 ◽

2006 ◽

Vol 346 (3) ◽

pp. 1033-1039 ◽

Author(s):

Masuhiro Nishimura ◽

Akiko Koeda ◽

Emako Suzuki ◽

Takefumi Shimizu ◽

Yuichi Kawano ◽

...

Keyword(s):

Mrna Expression ◽

Primary Cultures ◽

Rat Hepatocytes ◽

Housekeeping Genes ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme ◽

Enzyme Inducers

Download Full-text

Comparison of Inducibility of Sulfotransferase and UDP-Glucuronosyltransferase mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.23.45 ◽

2008 ◽

Vol 23 (1) ◽

pp. 45-53 ◽

Author(s):

Masuhiro Nishimura ◽

Akiko Koeda ◽

Takefumi Shimizu ◽

Mitsuo Nakayama ◽

Tetsuo Satoh ◽

...

Keyword(s):

Cynomolgus Monkey ◽

Primary Cultures ◽

Microsomal Enzyme ◽

Udp Glucuronosyltransferase ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text

Effect of microsomal enzyme inducers on carrier-mediated transport systems in isolated rat hepatocytes

Gastroenterology ◽

10.1016/0016-5085(78)90547-4 ◽

1978 ◽

Vol 75 (5) ◽

pp. 962

Author(s):

D.L. Eaton ◽

C.D. Klaassen

Keyword(s):

Rat Hepatocytes ◽

Transport Systems ◽

Microsomal Enzyme ◽

Isolated Rat Hepatocytes ◽

Carrier Mediated Transport ◽

Microsomal Enzyme Inducers ◽

Isolated Rat ◽

Enzyme Inducers

Download Full-text

Comparison of Inducibility of Multidrug Resistance (MDR)1, Multidrug Resistance-Associated Protein (MRP)1, and MRP2 mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.31.2068 ◽

2008 ◽

Vol 31 (11) ◽

pp. 2068-2072 ◽

Author(s):

Masuhiro Nishimura ◽

Akiko Koeda ◽

Hiroshi Morikawa ◽

Tetsuo Satoh ◽

Shizuo Narimatsu ◽

...

Keyword(s):

Multidrug Resistance ◽

Cynomolgus Monkey ◽

Primary Cultures ◽

Microsomal Enzyme ◽

Microsomal Enzyme Inducers ◽

Mdr 1 ◽

Enzyme Inducers

Download Full-text

Induction of T4 UDP-GT activity, serum thyroid stimulating hormone, and thyroid follicular cell proliferation in mice treated with microsomal enzyme inducers

Toxicology and Applied Pharmacology ◽

10.1016/s0041-008x(02)00071-6 ◽

2003 ◽

Vol 188 (1) ◽

pp. 6-13 ◽

Author(s):

Alan Hood ◽

Marcia L Allen ◽

YaPing Liu ◽

Jie Liu ◽

Curtis D Klaassen

Keyword(s):

Cell Proliferation ◽

Thyroid Stimulating Hormone ◽

Follicular Cell ◽

Microsomal Enzyme ◽

Thyroid Follicular Cell ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers ◽

Stimulating Hormone

Download Full-text

Differential Effects of Microsomal Enzyme Inducers on in Vitro Thyroxine (T4) and Triiodothyronine (T3) Glucuronidation

Toxicological Sciences ◽

10.1093/toxsci/55.1.78 ◽

2000 ◽

Vol 55 (1) ◽

pp. 78-84 ◽

Author(s):

A. Hood

Keyword(s):

Microsomal Enzyme ◽

Differential Effects ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text

Hexachlorobenzene: Member of a New Class of Hepatic Microsomal Enzyme Inducers

Biochemical Society Transactions ◽

10.1042/bst0030191 ◽

1975 ◽

Vol 3 (1) ◽

pp. 191-191

Author(s):

MICHAEL D. STONARD

Keyword(s):

Microsomal Enzyme ◽

New Class ◽

Hepatic Microsomal Enzyme ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text

POLYBROMINATED BIPHENYLS, POLYCHLORINATED NAPHTHALENES AND POLYCHLORINATED TERPHENYLS AS MICROSOMAL ENZYME INDUCERS

Toxicology of Halogenated Hydrocarbons ◽

10.1016/b978-0-08-027530-7.50013-3 ◽

1981 ◽

pp. 97-105 ◽

Author(s):

S. Safe ◽

L. Robertson ◽

A. Parkinson ◽

M. Shilling ◽

R. Cockerline ◽

...

Keyword(s):

Microsomal Enzyme ◽

Polychlorinated Naphthalenes ◽

Polybrominated Biphenyls ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text

2679. Modification of acrylamide neuropathy by microsomal-enzyme inducers

Food and Cosmetics Toxicology ◽

10.1016/0015-6264(74)90394-0 ◽

1974 ◽

Vol 12 (2) ◽

pp. 281-282

Keyword(s):

Microsomal Enzyme ◽

Microsomal Enzyme Inducers ◽

Acrylamide Neuropathy ◽

Enzyme Inducers

Download Full-text

Regulation of Rat Multidrug Resistance Protein 2 by Classes of Prototypical Microsomal Enzyme Inducers That Activate Distinct Transcription Pathways

Toxicological Sciences ◽

10.1093/toxsci/67.2.182 ◽

2002 ◽

Vol 67 (2) ◽

pp. 182-189 ◽

Author(s):

D. R. Johnson

Keyword(s):

Multidrug Resistance ◽

Multidrug Resistance Protein ◽

Microsomal Enzyme ◽

Multidrug Resistance Protein 2 ◽

Resistance Protein ◽

Microsomal Enzyme Inducers ◽

Enzyme Inducers

Download Full-text