Highly Sensitive Immunosensing of Carcinoembryonic Antigen Based on Gold Nanoparticles Functionalized PB@PANI Core-Shell Nanocubes as a Novel Signal Amplification Strategy

2021 ◽  
Author(s):  
Dexiang Feng ◽  
Lingzhi Chen ◽  
Menglan Fu ◽  
Peng Jiang ◽  
Xianhao Jiang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Carcinoembryonic Antigen ◽  
Signal Amplification ◽  
Core Shell ◽  
Highly Sensitive ◽  
Amplification Strategy

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

A novel chemiluminescence signal amplification strategy based on a capillary electrophoresis platform for highly sensitive competitive immunoassay of biomolecules

2018 ◽  
Vol 10 (46) ◽  
pp. 5499-5506 ◽  
Author(s):  
Min Shi ◽  
Jingjin Zhao ◽  
Shuting Li ◽  
Jianniao Tian ◽  
Shulin Zhao
Keyword(s):  
Gold Nanoparticles ◽  
Capillary Electrophoresis ◽  
Signal Amplification ◽  
Competitive Immunoassay ◽  
Highly Sensitive ◽  
Amplification Strategy

A novel chemiluminescence (CL) signal amplification strategy based on luminophore and antigen co-loaded gold nanoparticles was developed to improve the sensitivity of capillary electrophoresis CL assay.

A novel electrochemical immunosensor based on dual signal amplification of gold nanoparticles and telomerase extension reaction

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Dual Signal Amplification

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.

scholarly journals Optimization of the Electrodeposition of Gold Nanoparticles for the Application of Highly Sensitive, Label-Free Biosensor

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 50 ◽  
Author(s):  
Hao-Chun Chiang ◽  
Yanyan Wang ◽  
Qi Zhang ◽  
Kalle Levon
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Aqueous Electrolyte ◽  
Label Free ◽  
Reduction Step ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Amperometric Glucose Biosensors ◽  
Aunp Surface

A highly sensitive electrochemical biosensor with a signal amplification platform of electrodeposited gold nanoparticle (AuNP) has been developed and characterized. The sizes of the synthesized AuNP were found to be critical for the performance of biosensor in which the sizes were dependent on HAuCl4 and acid concentrations; as well as on scan cycles and scan rates in the gold electro-reduction step. Systematic investigations of the adsorption of proteins with different sizes from aqueous electrolyte solution onto the electrodeposited AuNP surface were performed with a potentiometric method and calibrated by design of experiment (DOE). The resulting amperometric glucose biosensors was demonstrated to have a low detection limit (> 50 μM) and a wide linear range after optimization with AuNP electrodeposition.

A dual-round signal amplification strategy for colorimetric/photoacoustic/fluorescence triple read-out detection of prostate specific antigen

2020 ◽  
Vol 56 (36) ◽  
pp. 4942-4945 ◽  
Author(s):  
Chao Jiang ◽  
Yan Huang ◽  
Ting He ◽  
Peng Huang ◽  
Jing Lin
Keyword(s):  
Prostate Specific Antigen ◽  
Immunosorbent Assay ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Enzyme Linked Immunosorbent Assay ◽  
Core Shell ◽  
Elisa System ◽  
System P ◽  
Amplification Strategy

A colorimetric/fluorescence/photoacoustic triple read-out detection of prostate specific antigen (PSA) was developed by using a silica coated Au@Ag core–shell nanorod (denoted Au@Ag@SiO2) based enzyme-linked immunosorbent assay (ELISA) system.

Reduced graphene oxide-gold nanoparticles-catalase-based dual signal amplification strategy in a spatial-resolved ratiometric electrochemiluminescence immunoassay

The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Jun-Tao Cao ◽  
Xiao-Long Fu ◽  
Fu-Rao Liu ◽  
Shu-Wei Ren ◽  
Yan-Ming Liu
Keyword(s):  
Gold Nanoparticles ◽  
Cardiac Troponin ◽  
Signal Amplification ◽  
Troponin I ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Reduced Graphene ◽  
Electrochemiluminescence Immunoassay ◽  
Amplification Strategy ◽  
Dual Signal Amplification

A novel spatial-resolved electrochemiluminescent (ECL) ratiometry for cardiac troponin I (cTnI) analysis was developed using resonance energy transfer (RET) and a coreactant consumption strategy for signal amplification.

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