scholarly journals The potential role of herbal medicines in the treatment of chronic stable angina pectoris: a review of key herbs, and as illustration, exploration of the Chinese herbal medicine approach

2012 ◽  
pp. 1 ◽  
Author(s):  
Kylie O'Brien ◽  
Luis Luis Vitetta
Medicine ◽  
2020 ◽  
Vol 99 (31) ◽  
pp. e21583 ◽  
Author(s):  
Mingqi Tu ◽  
Yongliang Jiang ◽  
Jie Yu ◽  
Binjun Liao ◽  
Jianqiao Fang

2009 ◽  
Vol 207 (2) ◽  
pp. 514-518 ◽  
Author(s):  
Rodrigo Estévez-Loureiro ◽  
Alejandro Recio-Mayoral ◽  
Juan A. Sieira-Rodríguez-Moret ◽  
Ernesto Trallero-Araguás ◽  
Juan Carlos Kaski

1984 ◽  
Vol 54 (7) ◽  
pp. 738-743 ◽  
Author(s):  
Nardev S. Khurmi ◽  
Michael J. Bowles ◽  
Martin J. O'Hara ◽  
V. Bala Subramanian ◽  
Edward B. Raftery

2018 ◽  
Vol 13 (1) ◽  
pp. 23 ◽  
Author(s):  
Jason M Tarkin ◽  
Juan Carlos Kaski ◽  
◽  
◽  

Nicorandil and long-acting nitrates are vasodilatory drugs used commonly in the management of chronic stable angina pectoris. Both nicorandil and long-acting nitrates exert anti-angina properties via activation of nitric oxide (NO) signalling pathways, triggering vascular smooth muscle cell relaxation. Nicorandil has additional actions as an arterial K+ATP channel agonist, resulting in more “balanced” arterial and venous vasodilatation than nitrates. Ultimately, these drugs prevent angina symptoms through reductions in preload and diastolic wall tension and, to a lesser extent, epicardial coronary artery dilatation and lowering of systemic blood pressure. While there is some evidence to suggest a modest reduction in cardiovascular events among patients with stable angina treated with nicorandil compared to placebo, this prognostic benefit has yet to be proven conclusively. In contrast, there is emerging evidence to suggest that chronic use of long-acting nitrates might cause endothelial dysfunction and increased cardiovascular risk in some patients.


2020 ◽  
Vol 50 (9) ◽  
pp. 773 ◽  
Author(s):  
Christina Kalvelage ◽  
Christian Stoppe ◽  
Nikolaus Marx ◽  
Gernot Marx ◽  
Carina Benstoem

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