Evaluation of ICCMS versus CAMBRA Caries Risk Assessment Models Acquisition on Treatment Plan in Young Adult Population: A Randomized Clinical Trial

Abstract Background Caries risk assessment is an essential element for managing and preventing dental caries in children. Individual caries risk assessment can be conducted to evaluate the presence or absence of single factors, or using multivariate models, a combination of factors. The subject has been extensively studied, but no previous research has compared whether a more elaborate and individualized method of caries risk benefits the patient than more straightforward strategies. Thus, this protocol evaluates the efficacy of two risk assessment methods for caries control in children, a simplified method based on caries experience evaluation and a multivariate method described in the literature. Methods This is a randomized, double-blind, controlled, parallel-treatment trial protocol. Two groups will be tested for two forms of caries risk assessment: an individualized and detailed multivariate method based on the guidelines of the Caries Care International 4D and another simplified process, based only on caries experience in primary and/or permanent dentition, considering the presence of decayed, missing and filled teeth using the DMFT/dmft index. Participants will be children aged 8 to 11 years, followed up at 12 and 24 months. The primary outcome will be a composite outcome representing the number of tooth surfaces requiring operative intervention (account variable). In addition, the Shapiro–Wilk normality test and Student's t-test will be performed. A multivariate analysis using negative binomial regression will compare groups in the intention-to-treat population, considering a two-tailed significance level of 5%. Discussion This is the first randomized clinical trial aiming to compare dental caries-related treatment and follow-up based on a detailed, multivariate and individualized assessment of caries risk in school-age children to a simpler risk assessment strategy based on caries experience. This study will define whether there are essential benefits to the patient that justify the choice of one method over the other. Trial registration Clinicaltrials.gov registration: NCT03969628. Registered on May 31th, 2019.

Download Full-text

Antimicrobial Effects of the Combination of Chlorhexidine and Fluoride Varnish in Young Adult Population

World Journal of Dentistry ◽

10.5005/jp-journals-10015-1175 ◽

2012 ◽

Vol 3 (4) ◽

pp. 290-293

Author(s):

BV Sreenivasa Murthy ◽

Swaroop Hegde ◽

KH Sumeera ◽

Sylvia Mathew ◽

John V George

Keyword(s):

Risk Assessment ◽

Young Adult ◽

Streptococcus Mutans ◽

Risk Group ◽

Adult Population ◽

Fluoride Varnish ◽

Caries Risk ◽

Moderate Risk ◽

Young Adult Population

ABSTRACT Aim (1) Use of a cariogram to evaluate the caries risk assessment in the students. (2) To evaluate the effectiveness of chlorhexidine and fluoride varnish applications on Streptococcus mutans at a 3-month follow-up. Materials and methods All the students of first year BDS of MS Ramaiah Dental College were included in this study. Caries risk assessment was done using a Cariogram and the students were divided into moderate and low risk groups. Streptococcus mutans count was assessed at baseline for both the groups. Chlorhexidine and fluoride varnish application was done in the moderate risk group at an interval of 1 week. After a period of 3 months, the Streptococcus mutans count was determined for both the groups and the results statistically analyzed. Results A significant reduction in the Streptococcus mutans count in the moderate risk group was seen at a 3 month follow-up. Conclusion The combined use of both chlorhexidine and fluoride varnish applications reduced the oral Streptococcus mutans count to significantly low levels in the study group at the 3-month follow-up. How to cite this article Sumeera KH, Mathew S, Hegde S, Murthy BVS, George JV. Antimicrobial Effects of the Combination of Chlorhexidine and Fluoride Varnish in Young Adult Population. World J Dent 2012;3(4):290-293.

Download Full-text

Are standardised caries risk assessment models effective?

Evidence-Based Dentistry ◽

10.1038/sj.ebd.6401338 ◽

2018 ◽

Vol 19 (4) ◽

pp. 102-103 ◽

Cited By ~ 1

Author(s):

Soraya C Leal

Keyword(s):

Risk Assessment ◽

Caries Risk ◽

Caries Risk Assessment ◽

Risk Assessment Models

Download Full-text

Assessing the Predictive Performance of Probabilistic Caries Risk Assessment Models: The Importance of Calibration

Caries Research ◽

10.1159/000507276 ◽

2020 ◽

Vol 54 (3) ◽

pp. 258-265

Author(s):

Mario Trottini ◽

Guglielmo Campus ◽

Denise Corridore ◽

Fabio Cocco ◽

Maria Grazia Cagetti ◽

...

Keyword(s):

Risk Assessment ◽

Predictive Performance ◽

Isotonic Regression ◽

Medical Decision ◽

Calibration Plot ◽

Caries Risk ◽

Caries Risk Assessment ◽

Risk Assessment Models ◽

Specificity And Sensitivity ◽

Calibration Methods

Probabilistic caries risk assessment models (P-CRA), such as the Cariogram, are promising tools to planning treatments in order to control and prevent caries. The usefulness of these models for informing patients and medical decision-making depends on 2 properties known as discrimination and calibration. Current common assessment of P-CRA models, however, ignores calibration, and this can be misleading. The aim of this paper was to provide tools for a proper assessment of calibration of the P-CRA models and improve calibration when lacking. A combination of standard calibration tools (calibration plot, calibration in-the-large, and calibration slope) and 3 novel measures of calibration (the Calibration Index and 2 related metrics, E50 and E90) are proposed to evaluate if a P-CRA model is well calibrated. Moreover, an approach was proposed and validated using data from a previous follow-up study performed on children evaluated by means of a reduced Cariogram model; Platt scaling and isotonic regression were applied showing a lack of calibration. The use of the Cariogram overestimates the actual risk of new caries for forecast probabilities <0.5 and underestimates the risk for forecast probabilities >0.6. Both Platt scaling and isotonic regression were able to significantly improve the calibration of the reduced Cariogram model, preserving its discrimination properties. The average specificity and sensitivity for both Platt scaling and isotonic regression using the cut-off point p= 0.5 were >83 and their sum well exceeded 160. The benefits of the proposed calibration methods are promising, but further research in this field is required.

Download Full-text