scholarly journals Randomized clinical trial to evaluate two methods of caries risk assessment in schoolchildren: the CARDEC-PEL 04 study protocol

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Aryane Marques Menegaz ◽  
Thays Torres do Vale Oliveira ◽  
Mariana Minatel Braga ◽  
Daniela Prócida Raggio ◽  
Maximiliano Sergio Cenci ◽  
...  

Abstract Background Caries risk assessment is an essential element for managing and preventing dental caries in children. Individual caries risk assessment can be conducted to evaluate the presence or absence of single factors, or using multivariate models, a combination of factors. The subject has been extensively studied, but no previous research has compared whether a more elaborate and individualized method of caries risk benefits the patient than more straightforward strategies. Thus, this protocol evaluates the efficacy of two risk assessment methods for caries control in children, a simplified method based on caries experience evaluation and a multivariate method described in the literature. Methods This is a randomized, double-blind, controlled, parallel-treatment trial protocol. Two groups will be tested for two forms of caries risk assessment: an individualized and detailed multivariate method based on the guidelines of the Caries Care International 4D and another simplified process, based only on caries experience in primary and/or permanent dentition, considering the presence of decayed, missing and filled teeth using the DMFT/dmft index. Participants will be children aged 8 to 11 years, followed up at 12 and 24 months. The primary outcome will be a composite outcome representing the number of tooth surfaces requiring operative intervention (account variable). In addition, the Shapiro–Wilk normality test and Student's t-test will be performed. A multivariate analysis using negative binomial regression will compare groups in the intention-to-treat population, considering a two-tailed significance level of 5%. Discussion This is the first randomized clinical trial aiming to compare dental caries-related treatment and follow-up based on a detailed, multivariate and individualized assessment of caries risk in school-age children to a simpler risk assessment strategy based on caries experience. This study will define whether there are essential benefits to the patient that justify the choice of one method over the other. Trial registration Clinicaltrials.gov registration: NCT03969628. Registered on May 31th, 2019.

Author(s):  
Vinaya Kumar Kulkarni ◽  
Shradhda S. Gavade ◽  
Neeta Padmawar ◽  
Shridhar Shetty ◽  
Sourabh Joshi

Introduction: Ability of an individual to taste phenylthiocarbamide (PTC) substance divides the population in tasters and non-tasters. The objective of this study was to investigate the relationship between the taste ability for PTC substance with BMI percentile, skeletal maturity and dental caries experience within taster and non-taster children of age 8-12 years. Hypotheses: Tasting ability for PTC affects the BMI percentile, skeletal maturity and dental caries experience and emerge as a useful caries risk assessment tool. Evaluation of Hypotheses (Materials and Method):  One hundred children of 8-12 years were randomly selected and their taste perception was assessed using PTC sensitivity test. Radiovisiography (RVG) of middle phalanx was obtained to determine the skeletal maturity by using Rajgopal and Kansal modification 2005. Anthropometric measurements were recorded to obtain BMI value and then BMI percentile was calculated using CDC Pediatric growth charts. For dental caries assessment, deft/DMFT scores were recorded. Results: The non-tasters had early skeletal maturation, higher caries experience and higher BMI percentile than the tasters. Conclusion and Clinical Relevance: PTC Sensitivity is a genetically controlled trait showing strong association with dental caries. From the results of this study we can conclude that the genetic ability of tasting PTC affects the BMI percentile, skeletal maturity and dental caries experience. Thus it can emerge as a useful caries risk assessment tool helping in planning the preventive measures and interceptive orthodontics in children.


2012 ◽  
Vol 3 (7) ◽  
pp. 223-225
Author(s):  
Catalina Iulia Saveanu ◽  
◽  
Lucia Barlean ◽  
Vlad Danila ◽  
Iulia Roxana Ionescu ◽  
...  

2006 ◽  
Vol 171 (2) ◽  
pp. 153-156
Author(s):  
Peter S. Richardson

2017 ◽  
Vol 63 (2) ◽  
pp. 57-60
Author(s):  
Cristian Funieru ◽  

Introduction. Caries risk assessment in individual patients is mandatory as it becomes a starting point for developing patient-centered preventive strategies. Any method designed for caries risk assessment should be based on the risk and protection factors involved. Material and method. The first part of this study consists of a fundamental research based on a meta-analysis style study of a number of 128 articles present in the main online databases. The other part of the study is dedicated to the development of a mathematical algorithm of dental caries risk. Results. The caries risk is based on the algorithm presented in this study which takes into account 8 risk or protection factors, their frequency and coefficients being found in the main publications flow and assigned according to an evaluation scale. Conclusions. Although at first glance it seems to be a simple and easy to apply mathematical formula, this algorithm must be validated in a future and specially designed study before it could be used on a large scale.


2019 ◽  
Vol 3 (5) ◽  
pp. 167-175
Author(s):  
Mohit Bansal ◽  
Ruhee Sangha ◽  
Simran Bahra ◽  
Navdeep Kaur Walia

Dental caries is a public health problem. A new interactive graphical computorised system was introducted which is belived to record the caries risk assessment in less time depending of number of factors. This paper focus on the different sectors used in cariogram and its importance in reducing the caries risk.


2013 ◽  
Vol 27 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Rodrigo Andrés Giacaman ◽  
Paulina Miranda Reyes ◽  
Valeria Bravo León

2017 ◽  
Vol 51 (3) ◽  
pp. 198-208 ◽  
Author(s):  
John S. Preisser ◽  
D. Leann Long ◽  
John W. Stamm

Marginalized zero-inflated count regression models have recently been introduced for the statistical analysis of dental caries indices and other zero-inflated count data as alternatives to traditional zero-inflated and hurdle models. Unlike the standard approaches, the marginalized models directly estimate overall exposure or treatment effects by relating covariates to the marginal mean count. This article discusses model interpretation and model class choice according to the research question being addressed in caries research. Two data sets, one consisting of fictional dmft counts in 2 groups and the other on DMFS among schoolchildren from a randomized clinical trial comparing 3 toothpaste formulations to prevent incident dental caries, are analyzed with negative binomial hurdle, zero-inflated negative binomial, and marginalized zero-inflated negative binomial models. In the first example, estimates of treatment effects vary according to the type of incidence rate ratio (IRR) estimated by the model. Estimates of IRRs in the analysis of the randomized clinical trial were similar despite their distinctive interpretations. The choice of statistical model class should match the study's purpose, while accounting for the broad decline in children's caries experience, such that dmft and DMFS indices more frequently generate zero counts. Marginalized (marginal mean) models for zero-inflated count data should be considered for direct assessment of exposure effects on the marginal mean dental caries count in the presence of high frequencies of zero counts.


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