scholarly journals Predicting Response to Total Neoadjuvant Treatment (TNT) in Locally Advanced Rectal Cancer Based on Multiparametric Magnetic Resonance Imaging: A Retrospective Study

2021 ◽  
Vol Volume 13 ◽  
pp. 5657-5669
Author(s):  
Ganlu Ouyang ◽  
Xibiao Yang ◽  
Xiangbing Deng ◽  
Wenjian Meng ◽  
Yongyang Yu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Retrospective Study ◽  
Magnetic Resonance ◽  
Locally Advanced ◽  
Neoadjuvant Treatment ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Resonance Imaging ◽  
Multiparametric Magnetic Resonance Imaging

Morphological and functional features prognostic factor of magnetic resonance imaging in locally advanced rectal cancer

2018 ◽  
Vol 60 (7) ◽  
pp. 815-825
Author(s):  
Roberta Fusco ◽  
Vincenza Granata ◽  
Daniela Rega ◽  
Carolina Russo ◽  
Ugo Pace ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Prognostic Factor ◽  
Locally Advanced ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Resonance Imaging ◽  
Functional Features

scholarly journals Predicting Response to Total Neoadjuvant Treatment (TNT) in Locally Advanced Rectal Cancer Based on Multiparametric Magnetic Resonance Imaging: A Retrospective Study

2020 ◽  
Author(s):  
Ganlu Ouyang ◽  
Xibiao Yang ◽  
Xiangbing Deng ◽  
Wenjian Meng ◽  
Yongyang Yu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Locally Advanced ◽  
Neoadjuvant Treatment ◽  
High Sensitivity ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Resonance Imaging ◽  
Low Sensitivity

Abstract Purpose: To investigate the potential value of magnetic resonance imaging (MRI) in predicting response relevance to total neoadjuvant treatment (TNT) in locally advanced rectal cancer.Methods: We analyzed MRI of 71 patients underwent TNT from 2015 to 2017 retrospectively. We categorized the response of TNT as CR (complete response) and non-CR, and high, moderate and low sensitivity. Logistic regression analysis was used to identify the best predictors of response. Diagnostic performance was assessed using receiver - operating characteristic curve analysis.Results: Post–ICT (induction chemotherapy) ∆TL (tumor length), post-CRT (concurrent chemoradiotherapy) ∆LNN (the numbers of lymph node metastases), post–CCT (consolidation chemotherapy) ∆SDWI (maximum cross-sectional area of tumor on diffusion-weighted imaging), post-CCT ADCT (the mean apparent diffusion coefficient values of tumor) and post-CCT ∆LNV (volume of lymph node) were the best CR predictors. Post-CRT EMVI (extramural vascular invasion) and post-CCT ∆ST2 (S on T2-weight) were the best significant factors for high sensitivity. Conclusions: Post-ICT ∆TL and post-CRT EMVI may an early predictor of CR and high sensitivity to TNT, respectively. The grouping scheme of CR and non–CR was more suitable for predicting response by MRI parameters than high, moderate and low sensitivity.Trial registration: retrospectively registered

Comparison of Magnetic Resonance Imaging and Histopathological Response to Chemoradiotherapy in Locally Advanced Rectal Cancer

2012 ◽  
Vol 19 (9) ◽  
pp. 2842-2852 ◽  
Author(s):  
Uday Bharat Patel ◽  
Gina Brown ◽  
Harm Rutten ◽  
Nicholas West ◽  
David Sebag-Montefiore ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Locally Advanced ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Resonance Imaging ◽  
Histopathological Response
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