ABSTRACT
The adrenal response to the infusion of various corticotrophin (ACTH) preparations and other hormones in the orchiectomized rhesus monkey has been measured by the excretion of 17-hydroxycorticosteroids, 17-ketosteroids, and 11-deoxy-17-ketosteroids. No difference was found in the response to genuine or synthetic ACTH. A response was demonstrated with 0.8 U or more of ACTH per 24 hours. No adrenal response was observed to infusions of various gonadotrophins, growth hormone, prolactin, α-melanocyte stimulating hormone, and thyroid stimulating hormone. Angiotensin selectively stimulated aldosterone excretion. No evidence was found for any selective stimulation of adrenal androgen production.
α-melanocyte stimulating hormone modulates the central acyl ghrelin-induced stimulation of feeding, gastrointestinal motility, and colonic secretion
