scholarly journals Sacroiliitis and osteomyelitis caused by serotype 3 Streptococcus pneumoniae in a previously healthy adult: a case report

2018 ◽  
Vol Volume 11 ◽  
pp. 1043-1046 ◽  
Author(s):  
Yoshiro Hadano ◽  
Bin Chang
2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Amresh Kumar Singh ◽  
Rungmei S. K. Marak ◽  
Anand Kumar Maurya ◽  
Manaswini Das ◽  
Vijaya Lakshmi Nag ◽  
...  

Nontuberculous mycobacteria (NTMs) are ubiquitous and are being increasingly reported as human opportunistic infection. Cutaneous infection caused by mixed NTM is extremely rare. We encountered the case of a 46-year-old female, who presented with multiple discharging sinuses over the lower anterior abdominal wall (over a previous appendectomy scar) for the past 2 years. Microscopy and culture of the pus discharge were done to isolate and identify the etiological agent. Finally, GenoType Mycobacterium CM/AS assay proved it to be a mixed infection caused byMycobacterium szulgaiandM. intermedium. The patient was advised a combination of rifampicin 600 mg once daily, ethambutol 600 mg once daily, and clarithromycin 500 mg twice daily to be taken along with periodic follow-up based upon clinical response as well as microbiological response. We emphasize that infections by NTM must be considered in the etiology of nonhealing wounds or sinuses, especially at postsurgical sites.


PEDIATRICS ◽  
1976 ◽  
Vol 58 (3) ◽  
pp. 378-381 ◽  
Author(s):  
Abel Paredes ◽  
Larry H. Taber ◽  
Martha D. Yow ◽  
Dorothy Clark ◽  
William Nathan

For more than 30 years, penicillin has been the agent of choice for pneumococcal infections. During this time the majority of strains of Streptococcus pneumoniae have been highly susceptible to penicillin. However, during the last ten years there have been sporadic reports of pneumococci with increased resistance to penicillin. The case report of an 18-month-old white boy with meningitis due to a strain of S. pneumoniae with increased resistance to penicillin is presented. The MIC of the organism to penicillin was 0.2µg/ml and the MBC 0.39µg/ml. The patient had normal immunity and no demonstrable sequestered focus of infection but failed to respond to appropriate doses of intravenous penicillin. Treatment with chloramphenicol caused a dramatic bacteriologic and clinical response. This experience reemphasizes the existence of pneumococcal strains of intermediate penicillin sensitivity and the importance of in vitro susceptibility tests.


2018 ◽  
Vol 4 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Ioana Raluca Chirteș ◽  
Dragos Florea ◽  
Carmen Chiriac ◽  
Oana Maria Mărginean ◽  
Cristina Mănășturean ◽  
...  

AbstractBackground: Known also as Osler’s triad, Austrian syndrome is a complex pathology which consists of pneumonia, meningitis and endocarditis, all caused by the haematogenous dissemination of Streptococcus pneumoniae. The multivalvular lesions are responsible for a severe and potential lethal outcome.Case report: The case of a 51-year-old female patient, with a past medical history of splenectomy, is presented. She developed bronchopneumonia, acute meningitis and infective endocarditis as a result of Streptococcus pneumoniae infection and subsequently developed multiple organ dysfunction syndromes which led to a fatal outcome. Bacteriological tests did not reveal the etiological agent. The histopathological examination showed a severe multivalvular endocarditis, while a PCR based molecular analysis from formalin fixed valvular tissue identified Streptococcus pneumoniae as the etiologic agent.Conclusions: The presented case shows a rare syndrome with a high risk of morbidity and mortality. Following the broad-spectrum treatment and intensive therapeutic support, the patient made unfavourable progress which raised differential diagnosis problems. In this case, the post-mortem diagnosis demonstrated multiple valvular lesions occurred as a result of endocarditis.


2013 ◽  
Vol 2 (2) ◽  
pp. 144-6 ◽  
Author(s):  
Selda Hancerli Torun ◽  
Bahar Calıskan ◽  
Ayper Somer ◽  
Nuran Salman ◽  
Nezahat Guler

1981 ◽  
Vol 95 (11) ◽  
pp. 1149-1151 ◽  
Author(s):  
B. Chattopadhyay

SummaryA 54-year-old man presented with candida tropicalis meningitis after exploration of the mastoid. He responded well to the combined intravenous administration of amphotericin B and 5 fluorocytosine. But 5 fluorocytosine had to be withdrawn when the candida proved to be resistant to this antifungal agent. However, the patient made an uneventful recovery. This seems to be the first report of a candida tropicalis meningitis in an otherwise healthy adult patient in this country.Infection of the meninges with candida remains rare (Black, 1970). Most of them are caused by candida albicans in patients with some other underlying conditions or those on prolonged antibiotic, corticosteroid, cytotoxic, immunosuppresive therapies. The purpose of this brief communication is to draw attention to its occurrence in a healthy patient following exploration of the mastoid for chronic suppurative middle-ear disease.


2003 ◽  
Vol 22 (3) ◽  
pp. 282-284 ◽  
Author(s):  
Dan Miron ◽  
Igor Dashkovsky ◽  
Miriam Zuker ◽  
Sergio Szvalb ◽  
Carlos Cozacov

2016 ◽  
Vol 102 (5) ◽  
Author(s):  
Olavegogeascoechea PA ◽  
Puyo CF ◽  
Serrano Riveros P ◽  
Núñez WD ◽  
Lomban E

1992 ◽  
Vol 3 (4) ◽  
pp. 185-188
Author(s):  
David R Burdge ◽  
Vincent C Woo ◽  
Patricia MA Ritchie

A Canadian adult with bacteremic pneumonia caused by a relatively penicillin-resistant (minimal inhibitory concentration 0.25 μg/mL) Streptococcus pneumoniae is reported, and the published literature regarding penicillin-resistant pneumococci in Canada reviewed. Although penicillin resistance has been reported infrequently to date, this case emphasizes the need for routine antimicrobial sensitivity testing of all pneumococci isolated from normally sterile sites, and for ongoing systematic surveillance for penicillin and other antibiotic resistance in Canada.


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