scholarly journals Severe Austrian Syndrome in an Immunocompromised Adult Patient – A Case Report

2018 ◽  
Vol 4 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Ioana Raluca Chirteș ◽  
Dragos Florea ◽  
Carmen Chiriac ◽  
Oana Maria Mărginean ◽  
Cristina Mănășturean ◽  
...  
Keyword(s):  
Case Report ◽  
Streptococcus Pneumoniae ◽  
Histopathological Examination ◽  
Fatal Outcome ◽  
Multiple Organ ◽  
Etiologic Agent ◽  
Acute Meningitis ◽  
History Of ◽  
Valvular Lesions ◽  
Formalin Fixed

AbstractBackground: Known also as Osler’s triad, Austrian syndrome is a complex pathology which consists of pneumonia, meningitis and endocarditis, all caused by the haematogenous dissemination of Streptococcus pneumoniae. The multivalvular lesions are responsible for a severe and potential lethal outcome.Case report: The case of a 51-year-old female patient, with a past medical history of splenectomy, is presented. She developed bronchopneumonia, acute meningitis and infective endocarditis as a result of Streptococcus pneumoniae infection and subsequently developed multiple organ dysfunction syndromes which led to a fatal outcome. Bacteriological tests did not reveal the etiological agent. The histopathological examination showed a severe multivalvular endocarditis, while a PCR based molecular analysis from formalin fixed valvular tissue identified Streptococcus pneumoniae as the etiologic agent.Conclusions: The presented case shows a rare syndrome with a high risk of morbidity and mortality. Following the broad-spectrum treatment and intensive therapeutic support, the patient made unfavourable progress which raised differential diagnosis problems. In this case, the post-mortem diagnosis demonstrated multiple valvular lesions occurred as a result of endocarditis.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

scholarly journals Scopolamine fatal outcome in an inmate after buscopan® smoking

2021 ◽  
Author(s):  
Sabina Strano-Rossi ◽  
Serena Mestria ◽  
Giorgio Bolino ◽  
Matteo Polacco ◽  
Simone Grassi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Drug Abuse ◽  
Muscarinic Receptors ◽  
Histopathological Examination ◽  
Fatal Outcome ◽  
Post Mortem ◽  
Butyl Bromide ◽  
Cannabis Abuse ◽  
Toxic Concentration ◽  
History Of

AbstractScopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of his cell after having smoked buscopan® tablets. Since both abuse of substances and recent physical assaults had been reported, we opted for a comprehensive approach (post-mortem computed tomography CT (PMCT), full forensic autopsy, and toxicology testing) to determine which was the cause of the death. Virtopsy found significant cerebral edema and lungs edema that were confirmed at the autopsy and at the histopathological examination. Scopolamine was detected in peripheral blood at the toxic concentration of 14 ng/mL in blood and at 263 ng/mL in urine, and scopolamine butyl bromide at 17 ng/mL in blood and 90 ng/mL in urine. Quetiapine, mirtazapine, lorazepam, diazepam, and metabolites and valproate were also detected (at therapeutic concentrations). Inmates, especially when they have a history of drug abuse, are at risk to use any substance they can find for recreational purposes. In prisons, active surveillance on the management and assumption of prescribed drugs could avoid fatal acute intoxication.

scholarly journals Multiple-System Atrophy in Long-Term Professional Painter: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Yusa Nagai ◽  
Riko Kitazawa ◽  
Miku Nakagawa ◽  
Munenori Komoda ◽  
Takeshi Kondo ◽  
...  
Keyword(s):  
Multiple System Atrophy ◽  
Medulla Oblongata ◽  
Neurodegenerative Disorder ◽  
Histopathological Examination ◽  
Neuronal Loss ◽  
Cytoplasmic Inclusion ◽  
Multiple Organ ◽  
Old Japanese ◽  
History Of

Introduction. Multiple system atrophy (MSA) is a rare and severe adult-onset, sporadic, and progressive neurodegenerative disorder. Here, we describe an autopsy case of MSA in a long-term professional painter. Although typical glial cytoplasmic inclusion (GCI) was not observed in a routine histological examination, strong α-synuclein immunostaining in the nucleus confirmed the diagnosis of MSA.Case Presentation. A 48-year-old Japanese man with a long occupational history of professional painter was sent to the emergency room, where he died of multiple organ failure. The patient had suffered tremors and inarticulateness at age 28, developed diabetes at 42 and was diagnosed with spinocerebellar degeneration at 46. A histopathological examination showed severe neuronal loss, gliosis, and tissue rarefaction in the paleostriatum, striate body of the substantia nigra, the pons, and the olivary nucleus of the upper medulla oblongata, intermediolateral of the spinal gray matter (sacral region). α-synuclein-positive GCI in oligodendroglia was occurred in the cerebral cortex, the midbrain, the medulla oblongata, and the spinal cord. These findings confirmed the presence of multiple-system atrophy (OPCA+SDS).Conclusion. Although the pathogenesis of MSA is still unclear, prolonged, and extensive exposure to organic solvents, together with a hyperglycemic morbidity attributed to diabetes, may have contributed to the onset and clinical course of the present case.

The fatal cholera like diarrhoea in coronavirus disease 2019(COVID-19)- a rare case report in toddler

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1894-1897
Author(s):  
Varsha Gajbhiye ◽  
Shubhangi Patil (Ganvir) ◽  
Sarika Gaikwad
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Digestive System ◽  
Gastrointestinal Symptoms ◽  
Female Child ◽  
Multiple Organ ◽  
Mild Case ◽  
Severe Dehydration ◽  
Rare Case Report ◽  
History Of

A 14-month female child came with complain of cholera like watery loose stool 10-12 times and vomiting 6-7 times, 24 hrs before admission. She was in severe dehydration, hypotension, unconscious with no recorded fever during her stay in hospital and no history of contact with COVID-19. Patient was COVID-19 positive Dehydration and hypotension was corrected, metabolic acidosis continued and eventually patient succumb due to multiple organ failure. This case report should arouse us to suspect COVID infection in every acute Gastroenteritis child who may not have any common symptoms as seen in COVID patient, also who have no history of significant contact with COVID positive patient in family. Some people with COVID-19 develop gastrointestinal symptoms either alone or with respiratory symptoms. Recently, researchers at Stanford University found that a third of patients they studied with a mild case of COVID-19 had symptoms affecting the digestive system. Another recent study Trusted Source published by researchers in Beijing found that anywhere from 3 to 79 percent of people with COVID-19 develop gastrointestinal symptoms.

scholarly journals OSTEOMA OF EXTERNAL AUDITORY CANAL: CASE REPORT

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 51-53
Author(s):  
Anshu Sood
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Temporal Bone ◽  
External Auditory Canal ◽  
Benign Tumor ◽  
Histopathological Examination ◽  
Otologic Surgery ◽  
Superior Part ◽  
History Of ◽  
Trauma Ct

ABSTRACT An osteoma of the external auditory canal is an uncommon benign tumor with an incidence estimated to be 0.05% of total otologic surgery. In head and neck, they most often arise in the frontoethmoidal region and rarely temporal bone. Osteomas usually asymptomatic and discovered incidentally. A 35 male presented with swelling in right posterior superior part of EAC, without any history of ear picking , swimming or trauma. CT temporal bone revealed a solitary osteoma, with was excised surgically. Histopathological examination confirmed Osteoma.

scholarly journals Ameloblastic Transformation of a Primarily Diagnosed Dentigerous Cyst of Jaw- A Rare Case Report

2021 ◽  
pp. 90-94
Author(s):  
Bose Surajit ◽  
Bhakta Ipsita ◽  
Karar Chandan Kumar ◽  
Singh Dharvind Kumar ◽  
Banerjee Abhishek
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histopathological Examination ◽  
Dentigerous Cyst ◽  
Facial Asymmetry ◽  
Biological Behavior ◽  
Unerupted Tooth ◽  
Patient Reported ◽  
Rare Case Report ◽  
History Of

The separation of the follicle from around the crown of an unerupted tooth causes formation of dentigerous cyst. It may undergo metaplasia in several cases. In this case a 30 year old female patient reported with a history of dentigerous cyst with respect to impacted 48. The swelling started growing gradually causing facial asymmetry. On intraoral examination the swelling seem to extend from 48 to 46 region and cortical plates were expanded. The histopathological examination revealed the sample to be cystic ameloblastoma (mural variety). This paper sends a message that the potential of a cyst should never be understated, instead it must be kept in an observation or understanding the biological behavior over a course of time.

scholarly journals Vaginal Adenosis in a 40-year-old Lady: A Case Report and Review of Literature

2013 ◽  
Vol 5 (2) ◽  
pp. 80-82
Author(s):  
Shamsun Nahar Begum Hena ◽  
Nasrin Akhter ◽  
Sakti Das ◽  
Afroza Kutubi
Keyword(s):  
Case Report ◽  
South Asian ◽  
Vaginal Discharge ◽  
Histopathological Examination ◽  
Rare Condition ◽  
Vaginal Wall ◽  
Review Of Literature ◽  
History Of ◽  
Unclear Etiology ◽  
Diffuse Lesion

ABSTRACT Vaginal adenosis, without a history of diethylstilbestrol (DES) exposure, is a rare condition with an unclear etiology. A 40- year-old female presented with complaints of persistent excessive watery vaginal discharge. On examination, there was red, patchy, diffuse lesion all over the vaginal wall and cervix. Histopathological examination of the lesion revealed vaginal adenosis. This case is presented here for its rarity. How to cite this article Hena SNB, Akhter N, Das S, Kutubi A. Vaginal Adenosis in a 40-year-old Lady: A Case Report and Review of Literature. J South Asian Feder Obst Gynae 2013;5(2):80-82.

scholarly journals Primary Malignant Melanoma of the Tonsil : A Case Report

2009 ◽  
Vol 22 (2) ◽  
pp. 279-281
Author(s):  
SM Badruddoza ◽  
S Naz
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Sore Throat ◽  
Male Patient ◽  
Clinical Examination ◽  
Histopathological Examination ◽  
Primary Malignant Melanoma ◽  
Polypoid Mass ◽  
Current Case ◽  
History Of

Malignant melanoma is a neoplasm of melanocytes. Primary malignant melanoma of the oronasal region is rare. When it does occur, it is difficult to manage, and the prognosis is not good. The current case was a 48 years old male patient who presented with history of sore throat, pain in left tonsillar region, hemoptysis with difficulty in swallowing. Clinical examination revealed a blackish ulcerated polypoid mass in the left palatine tonsil. Left sided tonsilectomy was done. Histopathological examination revealed primary malignant melanoma of the tonsil.TAJ 2009; 22(1): 279-281

scholarly journals An atypical case of rhinosporidiosis: a case report

2018 ◽  
Vol 4 (6) ◽  
pp. 1502
Author(s):  
Timna C. J. ◽  
Chandrika D.
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Granulomatous Lesion ◽  
Rhinosporidium Seeberi ◽  
Atypical Case ◽  
Endoscopic Excision ◽  
Inferior Meatus ◽  
History Of

<p class="abstract">Rhinosporidiosis is an infective chronic granulomatous lesion caused by an organism rhinosporidium seeberi, which is seen endemic in some parts of Asia. This organism is difficult to culture and the diagnosis is based on histopathological examination. This disease is more commonly seen in men, in second to third decade..<strong> </strong>This case report is regarding a case of a 55 years old lady with history of recurrent rhinosporidiosis in nose. The lesion was found to arise from the inferior meatus and was pale smooth  glistening in appearance, insensitive and does not bleed on touch. Site of origin of the polyp and the appearance was atypical of that of rhinosporidiosis. Patient was subjected for endoscopic excision and cauterisation of the base of the lesion and sent for histopathological examination .Biopsy confirmed the diagnosis of rhinosporidiosis.</p>

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