scholarly journals Guided bone regeneration with asymmetric collagen-chitosan membranes containing aspirin-loaded chitosan nanoparticles

2017 ◽  
Vol Volume 12 ◽  
pp. 8855-8866 ◽  
Author(s):  
Jiayu Zhang ◽  
Shiqing Ma ◽  
Zihao Liu ◽  
Hongjuan Geng ◽  
Xin Lu ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Chitosan Nanoparticles ◽  
Guided Bone Regeneration ◽  
Chitosan Membranes

Reinforced chitosan membranes by microspheres for guided bone regeneration

2018 ◽  
Vol 81 ◽  
pp. 195-201 ◽  
Author(s):  
Di Huang ◽  
Lulu Niu ◽  
Jian Li ◽  
Jingjing Du ◽  
Yan Wei ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Chitosan Membranes

scholarly journals A Study of Combining Elastin in the Chitosan Electrospinning to Increase the Mechanical Strength and Bioactivity

Marine Drugs ◽  
2021 ◽  
Vol 19 (3) ◽  
pp. 169
Author(s):  
Hengjie Su ◽  
Tomoko Fujiwara ◽  
Joel D. Bumgardner
Keyword(s):  
Bone Regeneration ◽  
Protein Extraction ◽  
Guided Bone Regeneration ◽  
Contact Angles ◽  
In Vivo Studies ◽  
Fiber Morphology ◽  
Water Contact ◽  
Degradation Rates ◽  
Chitosan Membranes

While electrospun chitosan membranes modified to retain nanofibrous morphology have shown promise for use in guided bone regeneration applications in in vitro and in vivo studies, their mechanical tear strengths are lower than commercial collagen membranes. Elastin, a natural component of the extracellular matrix, is a protein with extensive elastic property. This work examined the incorporation of elastin into electrospun chitosan membranes to improve their mechanical tear strengths and to further mimic the native extracellular composition for guided bone regeneration (GBR) applications. In this work, hydrolyzed elastin (ES12, Elastin Products Company, USA) was added to a chitosan spinning solution from 0 to 4 wt% of chitosan. The chitosan–elastin (CE) membranes were examined for fiber morphology using SEM, hydrophobicity using water contact angle measurements, the mechanical tear strength under simulated surgical tacking, and compositions using Fourier-transform infrared spectroscopy (FTIR) and post-spinning protein extraction. In vitro experiments were conducted to evaluate the degradation in a lysozyme solution based on the mass loss and growth of fibroblastic cells. Chitosan membranes with elastin showed significantly thicker fiber diameters, lower water contact angles, up to 33% faster degradation rates, and up to seven times higher mechanical strengths than the chitosan membrane. The FTIR spectra showed stronger amide peaks at 1535 cm−1 and 1655 cm−1 in membranes with higher concentrated elastin, indicating the incorporation of elastin into electrospun fibers. The bicinchoninic acid (BCA) assay demonstrated an increase in protein concentration in proportion to the amount of elastin added to the CE membranes. In addition, all the CE membranes showed in vitro biocompatibility with the fibroblasts.

scholarly journals Bioactive Glass Flakes as Innovative Fillers in Chitosan Membranes for Guided Bone Regeneration

2021 ◽  
pp. 2101042
Author(s):  
Huijun Zhang ◽  
Jingjing Wu ◽  
Ying Wan ◽  
Stefan Romeis ◽  
Julian D. Esper ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Chitosan Membranes

SauFRa technique for the fixation of resorbable membranes in horizontal guided bone regeneration - a technical report

2020 ◽  
Author(s):  
Saurabh Mohan Kamat ◽  
Rakshit Khandeparker ◽  
Francis Akkara ◽  
Vikas Dhupar ◽  
Ashwin Mysore
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Novel Technique ◽  
Technical Report ◽  
Suturing Techniques ◽  
Graft Migration

Membrane fixation in guided bone regeneration (GBR) has been traditionally achieved using resorbable pins, titanium tacks or miniscrews. However, these techniques are marredwith a number of clinical challenges. This article presents the “SauFRa” technique, a novel technique for stabilization of resorbable membranes in both, single as well as multiple implant sites while avoiding the shortcomings of other suturing techniques described in literature. Furthermore, the technique also eliminates the possibility of complications observed when using resorbable pins, titanium tacks or miniscrews, such as damage to adjacent roots during insertion. The authors’ employed this technique in 89 patients (51 male and 35 female) and found no complications like tissue dehiscence, infection or graft migration.

REGENERAÇÃO ÓSSEA GUIADA DE ALVÉOLOS DE EXTRAÇÃO DENTÁRIO- UMA REVISÃO

2016 ◽  
Vol 1 (45) ◽  
Author(s):  
Bruno Pires Miranda
Keyword(s):  
Bone Regeneration ◽  
Tooth Extraction ◽  
Oral Surgery ◽  
Guided Bone Regeneration ◽  
The Body ◽  
Synthetic Material ◽  
Dynamic Changes ◽  
Tooth Socket ◽  
Ability To Regenerate ◽  
Implant Dentistry

Resumo O osso é um tecido conjuntivo especializado, vascularizado e dinâmico que se modifica ao longo do organismo. Quando lesado, possui uma capacidade única de regeneração e reparação sem a presença de cicatrizes, mas em algumas situações devido tamanho do defeito ósseo não se regenera por completo. Assim, se faz necessária a realização de procedimentos de regeneração óssea guiada. Para isso, o implantodontista deve conhecer as bases biológicas da regeneração óssea guiada alveolar e suas indicações. Nesta revisão foram abordadas indicações, vantagens e tipos de biomateriais utilizados para preenchimento do alvéolo dentário imediatamente após a extração dentária sempre que o objetivo for à reabilitação através da instalação de implantes. Mesmo este, biomateriais, apresentando inúmeras qualidades, estudos ainda devem ser feitos a fim de obter a cada dia, um material sintético compatível com o tecido ósseo perdido em quantidades adequadas sem necessitar de cirurgias extra-bucais.ABSTRACT Bone is a specialized vascularized connective tissue that dynamic changes throughout the body. When injured, it has a unique ability to regenerate and repair without the presence of scars, but in some situations due to size of the bone defect does not regenerate completely. Thus, it is necessary to perform guided bone regeneration procedures. For this, the implant dentistry must know the biological bases of alveolar guided bone regeneration and its indications. In this review were addressed indications, advantages and types of biomaterials used for filling the tooth socket immediately after the tooth extraction whenever the goal is rehabilitation through implants installation. Even this, biomaterials, having several qualities, further studies must be done to obtain each day, a synthetic material compatible with the bone tissue lost in proper amounts without the need of extra-oral surgery.

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