scholarly journals Analysis of Peanut Allergen Components Sensitization and Cross Reaction with Pollen Allergen in Chinese Southerners with Allergic Rhinitis and/or Asthma

2021 ◽  
Vol Volume 14 ◽  
pp. 1285-1293
Author(s):  
Wenting Luo ◽  
Shuwen Yang ◽  
Huimin Huang ◽  
Liting Wu ◽  
Zhangkai J Cheng ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Cross Reaction ◽  
Pollen Allergen ◽  
Peanut Allergen ◽  
Allergen Components

Serum immunoglobulin E reactivity to cross-reacting panallergen components in north-eastern Poland patients pollen sensitized

2020 ◽  
Vol 41 (3) ◽  
pp. 183-191
Author(s):  
Krzysztof Kowal ◽  
Agnieszka Pampuch ◽  
Ewa Sacharzewska ◽  
Ewa Swiebocka ◽  
Zenon Siergiejko ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Allergen Immunotherapy ◽  
Immunoglobulin E ◽  
Pollen Allergy ◽  
Serum Ige ◽  
Ige Reactivity ◽  
Allergen Components ◽  
North Eastern ◽  
Allergen Sources ◽  
Seasonal Pollen

Background: The presence of immunoglobulin E (IgE), which cross-reacts with allergen components, such as profilins, polcalcins, and cross-reacting carbohydrate determinants (CCD), creates a problem when selecting patients for allergen immunotherapy by using conventional methods. The aim of this study was to evaluate the prevalence of sensitization to profilins, polcalcins, and CCDs in patients with seasonal pollen allergic rhinitis. Methods: The study was performed on a group of 112 patients with seasonal pollen allergic rhinitis, ages 14 to 55 years, with sensitization to at least one seasonal allergen (IgE > 0.7 kUA/L). The presence of IgE sensitization to recombinant (r) Bet v 2, rPhl p 12, rBet v 4, rPhl p 7, and CCDs, in addition to rBet v 1, rPhl p 1, rPhl p 5, was evaluated by using a multiparameter immunoblot. Results: Among the studied patients, 64.3, 80.4, and 41.1% were sensitized to birch, timothy grass, and mugwort pollen, respectively. Sensitization to profilins rBet v 2/Phl p 12 was demonstrated in 28.6%, to polcalcins Bet v 4/Phl p 7 in 8.9%, and to CCDs in 25%. In 29.3%, serum IgE reactivity to any of the cross-reactive components could be demonstrated. Serum IgE reactivity to rBet v 2 was always accompanied by IgE reactivity to rPhl p 12, and IgE reactivity to rBet v 4 was always accompanied by IgE reactivity to rPhl p 7. Among the patients with pollinosis co-sensitized to at least two allergen sources according to extract-based diagnosis, possible false-positive results due to sensitization to cross-reactive components were detected in 17.9%. Conclusion: Evaluation of sensitization to cross-reacting components may be useful in evaluation of patients with pollen allergy who are being assessed for allergen immunotherapy to optimize the constitution of their immunotherapy vaccines.

Measurement of IgE to pollen allergen components is helpful in selecting patients for immunotherapy

2013 ◽  
Vol 111 (4) ◽  
pp. 295-297 ◽  
Author(s):  
Antonio Letrán ◽  
Marisa Espinazo ◽  
Francisco Moreno
Keyword(s):  
Pollen Allergen ◽  
Allergen Components

scholarly journals Relevant Patient Benefit of Sublingual Immunotherapy with Birch Pollen Allergen Extract in Allergic Rhinitis: An Open, Prospective, Non-Interventional Study

2020 ◽  
Vol 37 (6) ◽  
pp. 2932-2945 ◽  
Author(s):  
Christine Blome ◽  
Meike Hadler ◽  
Efstrathios Karagiannis ◽  
Julia Kisch ◽  
Christopher Neht ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Sublingual Immunotherapy ◽  
Birch Pollen ◽  
Pollen Allergen ◽  
Allergen Extract ◽  
Patient Benefit ◽  
Interventional Study ◽  
Birch Pollen Allergen

scholarly journals Specific IgE response to different grass pollen allergen components in children undergoing sublingual immunotherapy

2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Francesco Marcucci ◽  
Laura Sensi ◽  
Cristoforo Incorvaia ◽  
Ilaria Dell’Albani ◽  
Giuseppe Di Cara ◽  
...  
Keyword(s):  
Grass Pollen ◽  
Sublingual Immunotherapy ◽  
Specific Ige ◽  
Pollen Allergen ◽  
Allergen Components ◽  
Grass Pollen Allergen ◽  
Ige Response

scholarly journals The presence of aeroallergens in food products: a potential risk for the patient with allergic rhinitis

2018 ◽  
Vol 8 (29) ◽  
pp. 11-15
Author(s):  
Florin-Dan Popescu ◽  
Mariana Vieru
Keyword(s):  
Allergic Rhinitis ◽  
Climate Changes ◽  
Food Contamination ◽  
Pollen Grains ◽  
Food Products ◽  
Allergic Reactions ◽  
Pollen Allergens ◽  
Allergen Components ◽  
Potential Risks ◽  
Edible Products

Abstract Clinical entities of food allergy in allergic rhinitis patients due to IgE-sensitization to cross-reactive aeroallergen and food allergen components are well described, but less data are available regarding allergic reactions to foods containing aeroallergens, either due to food contamination, such as oral mite anaphylaxis, or due to their natural presence in the edible products, such as pollen grains in honey and bee products. There are some potential risks for allergic rhinitis subjects due to ingestion of food products containing domestic mite, insect, fungal and pollen allergens. The knowledge of these risks is useful for the allergists and ENT specialists, especially in the context of climate changes with warmer periods facilitating mite growth in flours, and of increase use of phytotherapy and apitherapy products containing pollen grains.

scholarly journals REMOTE RESULTS OF SUBLINGUAL ALLERGENSPECIFICIMMUNOTHERAPY AT POLLINOSIS PATIENTS - FIVE YEARS'RESEARCH

2011 ◽  
Vol 8 (3) ◽  
pp. 31-36
Author(s):  
Marina Valentinovna Manzhos ◽  
E S Fedenko ◽  
M A Myagkova ◽  
G A Keropyan ◽  
S A Shkadov ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Total Dose ◽  
Pollen Season ◽  
Clinical Results ◽  
Pollen Allergen ◽  
The Third ◽  
Asthma Symptoms ◽  
Clinical Efficiency ◽  
Highly Effective

Background. The purpose of the work was to investigate remote and preventive results of sublingual allergenspecific immunotherapy (SLiT) at pollinosis patients. Methods. 25 patients at the age from 19 till 50 years old with an allergic rhinitis and asthma (35%) sensitized to artemisia were under the supervision. SLiT was administered in the period since September 2003 till May 2006 with pollen allergen («Sevapharma», Czech Republik). The average total dose of the allergen per one patient at the end of the third year was 189999 PNU. Clinical efficiency was estimated annually and in 30 months after discontinuation of SLiT. Frequency and intensity of symptoms during the pollen season, requirement for medicines, FEV1 parameters and results of prick tests were considered. Results. good and excellent results after three courses of immunotherapy demonstrated 23 patients (92%), satisfactory - 2 patients (8%). The results were remained at 22 patients (88%) within the next 30 months. at 3 patients (12%) increase of rhinoconjunctivitis symptoms was noted, and 3 (12%) showed expansion of a sensibilisation spectrum. Further increase of intensity and frequency of asthma symptoms, decrease in indicators FEV1 was not registered. Conclusion. SLiT is a highly effective method of treatment for patients with seasonal rhinitis and leads to the clinical results remaining more than 2 years at the majority of patients.

IgE to peanut allergen components: relation to peanut symptoms and pollen sensitization in 8-year-olds

Allergy ◽  
2010 ◽  
Author(s):  
A. Asarnoj ◽  
R. Movérare ◽  
E. Östblom ◽  
M. Poorafshar ◽  
G. Lilja ◽  
...  
Keyword(s):  
Peanut Allergen ◽  
Allergen Components

scholarly journals Altered Expression of IL-18, IL-18 Binding Protein and IL-18 Receptor in Blood Monocytes of Patients with Allergic Rhinitis

2020 ◽  
Author(s):  
Junling Wang ◽  
Fangqiu Gu ◽  
Zhi Li ◽  
Mengmeng Zhan ◽  
Ling Wang ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Binding Protein ◽  
Flow Cytometric Analysis ◽  
Lavage Fluid ◽  
Causative Factor ◽  
Pollen Allergen ◽  
Ar Model ◽  
Blood Monocytes ◽  
Altered Expression ◽  
Elevated Expression

Abstract Background: Interleukin (IL)-18 is emerging as an attractive participant in allergic rhinitis (AR). However, correlation of IL-18 with IL-18 binding protein (BP) in plasma, and expression of IL-18, IL-18BP and IL-18 receptor (R) in AR blood monocytes remain obscure. We therefore investigated IL-18, IL-18BP and IL-18R expression in monocytes using flow cytometric analysis, murine AR model, and quantitative real-time PCR in the present study. Results: Plasma IL-18 and IL-1β in AR patients was higher than those in healthy control subjects. Free (f)IL-18 had a high correlation with IL-18BP, IL-1β and TNF-α in AR plasma. Proportion of IL-18+ monocytes was increased, whereas IL-18BP+ monocytes were decreased in blood of patients with AR. It was found that Platanus pollen allergen extract provoked the elevated expression of IL-18 and IL-18R in AR blood monocytes. Dermatophagoides pteronyssinus, Artemisia sieversiana wild and Platanus pollen allergen extracts enhanced IL-18R protein and mRNA expression in isolated primary monocytes from AR patients. Moreover, numbers of macrophages and IL-18R+ macrophages in nasal lavage fluid (NLF) were increased, and levels of IL-18 in both plasma and NLF were elevated in AR mice. Conclusions: These suggest that IL-18 is likely to participate in the development of AR as a causative factor; therefore, it could be a therapeutic target for AR.

Tryptophan metabolism in allergic rhinitis: The effect of pollen allergen exposure

2010 ◽  
Vol 71 (9) ◽  
pp. 911-915 ◽  
Author(s):  
Giorgio Ciprandi ◽  
Mara De Amici ◽  
Mariangela Tosca ◽  
Dietmar Fuchs
Keyword(s):  
Allergic Rhinitis ◽  
Allergen Exposure ◽  
Pollen Allergen ◽  
Tryptophan Metabolism
Sign in / Sign up

Export Citation Format

Share Document