Adverse events and patients’ perceived health-related quality of life at the end of multidrug-resistant tuberculosis treatment in Namibia

IntroductionThe sequelae of multidrug-resistant tuberculosis (MDR-TB) are poorly understood and inconsistently reported. We will aim to assess the existing evidence for the clinical, psychological, social and economic sequelae of MDR-TB and to assess the health-related quality of life in patients with MDR-TB.Methods and analysisWe will perform a systematic review and meta-analysis of published studies reporting sequelae of MDR-TB. We will search PubMed, SCOPUS, ProQuest, Web of Science and PsychINFO databases up to 5 September 2017. MDR-TB sequelae will include any clinical, psychological, social and economic effects as well as health-related quality of life that occur after MDR-TB treatment or illness. Two researchers will screen the titles and abstracts of all citations identified in our search, extract data, and assess the scientific quality using standardised formats. Providing there is appropriate comparability in the studies, we will use a random-effects meta-analysis model to produce pooled estimates of MDR-TB sequelae from the included studies. We will stratify the analyses based on treatment regimen, comorbidities (such as HIV status and diabetes mellitus), previous TB treatment history and study setting.Ethics and disseminationAs this study will be based on published data, ethical approval is not required. The final report will be disseminated through publication in a peer-reviewed scientific journal and will also be presented at relevant conferences.PROSPERO registration numberCRD42017073182.

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Mental health disorders, social stressors, and health-related quality of life in patients with multidrug-resistant tuberculosis: A systematic review and meta-analysis

Journal of Infection ◽

10.1016/j.jinf.2018.07.007 ◽

2018 ◽

Vol 77 (5) ◽

pp. 357-367 ◽

Cited By ~ 8

Author(s):

Kefyalew Addis Alene ◽

Archie C A Clements ◽

Emma S McBryde ◽

Ernesto Jaramillo ◽

Knut Lönnroth ◽

...

Keyword(s):

Meta Analysis ◽

Multidrug Resistant ◽

Health Related Quality ◽

Social Stressors ◽

Resistant Tuberculosis ◽

Multidrug Resistant Tuberculosis ◽

Related Quality ◽

Health Related ◽

Health Disorders

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Is the glass half-empty or half-full? The role of optimism in protective health behaviors and perceived health-related quality of life in a Colombian sample

PsycEXTRA Dataset ◽

10.1037/e546872013-237 ◽

2013 ◽

Author(s):

Susana C. Barradas ◽

Carolyn Finck ◽

Diana Agudelo

Keyword(s):

Quality Of Life ◽

Health Behaviors ◽

Perceived Health ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Associations between fitness levels and self-perceived health-related quality of life in community - dwelling for a group of older females

BMC Public Health ◽

10.1186/s12889-020-08473-3 ◽

2020 ◽

Vol 20 (S1) ◽

Author(s):

Ferenc Ihász ◽

Nikolett Schulteisz ◽

Kevin J. Finn ◽

Krisztina Szabó ◽

Judit Gangl ◽

...

Keyword(s):

Quality Of Life ◽

Perceived Health ◽

Community Dwelling ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Fitness Levels

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47 Dual Tasking in Older Women: Physical Activity or Else?

Age and Ageing ◽

10.1093/ageing/afz164.47 ◽

2019 ◽

Vol 48 (Supplement_4) ◽

pp. iv9-iv12

Author(s):

Jennifer Muhaidat ◽

Emad Al-Yahya ◽

Maha Mohammad ◽

Dania Qutishat ◽

Rasha Okasheh ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Older Adults ◽

Older Women ◽

Stride Length ◽

Perceived Health ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract Background The interplay between gender, Physical Activity (PA) and Dual Task (DT) gait in older adults is unclear. This study aimed to address DT gait based on gender and PA level in older adults. Methods Gait measures were collected using an Inertial Measurement Unit (IMU) during the 10-meter and Timed Up and Go (TUG) tests in single and DT conditions. Global Physical Activity Questionnaire (GPAQ) was used to measure PA. A total of 120 community-dwelling older adults (81 women and 39 men) took part. Participants were divided according to gender and PA level into four groups (women achieving (WA = 31), women not achieving (WN = 50), men Achieving (MA = 29) and men not achieving (MN = 10)). The achievement of PA was determined by total Metabolic Equivalent (MET) – Minute/week ≥ 600. Cognition, health-related quality of life, falls history and health status was measured. Results Women had poorer performance in time, gait velocity and stride length regardless of PA level. The cognitive condition had the greatest effect on gait parameters in all groups, except for stride length which decreased more under the motor condition. Women who did not achieve the PA guidelines had poorer perceived health-related quality of life than men who achieved and did not achieve the guidelines. Conclusions The findings suggest that women, regardless of PA level, experience greater deterioration under ST and DT conditions in 10-meter walk and TUG tests in terms of time and gait measures such as velocity and stride length. This interplay cannot be explained by PA alone since it could be reflective of poorer perceived health and frailty in older women. These findings are considered of importance when planning DT and PA interventions that aim to increase PA levels and promote function in older women.

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