scholarly journals PREVALENCE OF PLASMID MEDIATED AMINOGLYCOSIDE MODIFYING ENZYMES IN PSEUDOMONAS AERUGINOSA IN HOSPITALIZED PATIENTS AT A TERTIARY CARE CENTRE.

2019 ◽  
Vol 7 (2) ◽  
pp. 273-280
Author(s):  
Santanu Hazra ◽  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Tertiary Care ◽  
Hospitalized Patients ◽  
Care Centre ◽  
Tertiary Care Centre

The laboratory diagnosis of Pseudomonas aeruginosa that produce metallo-β-lactamases in a Dutch tertiary care centre

2011 ◽  
Vol 43 (8) ◽  
pp. 596-602 ◽  
Author(s):  
Akke K. van Der Bij ◽  
Marco Mol ◽  
Mireille van Westreenen ◽  
Wil H. F. Goessens ◽  
Johann D. D. Pitout
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Care Centre ◽  
Tertiary Care Centre

scholarly journals Depression and its Cure: A Drug Utilization Study from a Tertiary Care Centre of Western Nepal

2011 ◽  
Vol 1 (5) ◽  
pp. 144-152 ◽  
Author(s):  
Indrajit Banerjee ◽  
Bedanta Roy ◽  
Indraneel Banerjee ◽  
Brijesh Sathian ◽  
Monami Mondal ◽  
...  
Keyword(s):  
Major Depression ◽  
Drug Utilization ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Tertiary Care ◽  
Hospitalized Patients ◽  
Care Centre ◽  
Utilization Pattern ◽  
Monthly Income ◽  
Drug Utilization Study ◽  
Tertiary Care Centre

Background: According to WHO, it is estimated that major depression would be the second most leading cause of disability in the world by 2020. Drug utilization study is defined as study of the marketing, distribution, prescription and use of drugs in a society highlighting on the resulting medical, social and economic consequences. The main objective of this study was to find the utilization pattern of antidepressants prescribed in a tertiary care centre with major depression in hospitalized patients of Western Nepal.Methods: A hospital based observational study was done between 1st October 2009 and 31st March 2010 at Psychiatry Ward of Manipal Teaching Hospital, Nepal. Both qualitative and quantitative data was collected from bed side. The outcome variables were essential drug, generic and trade, treatment, groups of antidepressants and antidepressants used. The explanatory variables were age, gender, monthly income, employment of the patient. Z test and logistic regression was used for the analysis. P-value < 0.05 was considered to be statistically significant. This is the first study done to understand the utilization pattern of antidepressant drugs in hospitalized patients in Nepal.Results: Among the 240 psychiatric patients studied, 38 (15.8%) cases were suffering from major depression. Male and female patients were 44.7% and 55.3% respectively, 95% CI [28.9, 60.5 and 39.5, 71.1]. Depression was more common in housewives (42.1%) followed by teachers 18.4% and students 10.5%. Fluoxetine was the commonest antidepressants to be prescribed 42.1% followed by Amitriptyline 26.3%, Trazodone 21.1% etc. Psychiatrists has a tendency of prescribing essential drugs if monthly income <10000, 1.063 times as compared to monthly income >10000, 2.63 times more in Hindus and 1.197 times more in Brahmins than any other ethnic groups. 9.179 times more tendency of prescribing antidepressants by trade names in case of unemployed patients as compared to employed patients in Nepal.Conclusion: According to the utilization pattern of antidepressants it was found that among the Selective serotonin reuptake inhibitors Fluoxetine was used relatively higher than conventional drugs like Tricyclic antidepressants, recommend that there is a trend of using Typical antidepressants drugs for depression rather than Newer antidepressants.DOI: http://dx.doi.org/10.3126/nje.v1i5.6152 Nepal Journal of Epidemiology 2011;1 (5):144-52 

scholarly journals Study of bacterial pathogens causing chronic suppurative otitis media and the antibiotic susceptibility pattern of the isolates at a tertiary care centre in Kochi

2020 ◽  
Vol 6 (4) ◽  
pp. 714
Author(s):  
Geetha Nair ◽  
Tanya Tonny Mampilly ◽  
Bindhu Vasudevan ◽  
J. Lancy
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Tertiary Care ◽  
Drug Resistant ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Resistant Strains ◽  
Drug Resistant Strains

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity presenting with recurrent ear discharges through a tympanic membrane perforation. Complications of CSOM were frequent in pre-antibiotic era. Injudicious use of antibiotics led to the emergence of multi-drug resistant strains and complications in return. To isolate the organisms associated with CSOM in a tertiary care centre and to detect their antibiogram.</p><p class="abstract"><strong>Methods:</strong> In this clinical, prospective, cross sectional study, a total of 100 patients clinically diagnosed with CSOM were enrolled from January to December 2019 (1 year).  </p><p class="abstract"><strong>Results:</strong> Of the 100 samples collected, predominant bacteria were isolated in 58 patients (58%). The most common isolate was <em>Pseudomonas aeruginosa</em> (29 isolates) followed by <em>Staphylococcus aureus</em> (24), <em>Klebsiella</em> species (3) and 1 isolate each of <em>Pneumococci</em> and <em>Acinetobacter</em> species. Among the 29 isolates of <em>Pseudomonas aeruginosa</em>, 8 (28%) were multidrug resistant. Sensitivity was 100% to imipenem followed by 97% to meropenem,79% to gentamicin, 76% to amikacin, 66% to ciprofloxacin, 41% to piperacillin tazobactam and 17% to ceftazidime. Of the 24 isolates of <em>Staphylococcus aureus</em>, 4 (16%) were methicillin resistant <em>Staphylococcus aureus</em> (MRSA).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas aeruginosa was the most common isolate, of which 28% were multi drug resistant. This calls for the judicious use of antibiotics and alternative measures for treatment of drug resistant strains. Formulating an antibiotic policy based on the local antibiogram can help in preventing the emergence and spread of resistant pathogens.</p>

Sign in / Sign up

Export Citation Format

Share Document