scholarly journals Study of bacterial pathogens causing chronic suppurative otitis media and the antibiotic susceptibility pattern of the isolates at a tertiary care centre in Kochi

Author(s):  
Geetha Nair ◽  
Tanya Tonny Mampilly ◽  
Bindhu Vasudevan ◽  
J. Lancy

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity presenting with recurrent ear discharges through a tympanic membrane perforation. Complications of CSOM were frequent in pre-antibiotic era. Injudicious use of antibiotics led to the emergence of multi-drug resistant strains and complications in return. To isolate the organisms associated with CSOM in a tertiary care centre and to detect their antibiogram.</p><p class="abstract"><strong>Methods:</strong> In this clinical, prospective, cross sectional study, a total of 100 patients clinically diagnosed with CSOM were enrolled from January to December 2019 (1 year).  </p><p class="abstract"><strong>Results:</strong> Of the 100 samples collected, predominant bacteria were isolated in 58 patients (58%). The most common isolate was <em>Pseudomonas aeruginosa</em> (29 isolates) followed by <em>Staphylococcus aureus</em> (24), <em>Klebsiella</em> species (3) and 1 isolate each of <em>Pneumococci</em> and <em>Acinetobacter</em> species. Among the 29 isolates of <em>Pseudomonas aeruginosa</em>, 8 (28%) were multidrug resistant. Sensitivity was 100% to imipenem followed by 97% to meropenem,79% to gentamicin, 76% to amikacin, 66% to ciprofloxacin, 41% to piperacillin tazobactam and 17% to ceftazidime. Of the 24 isolates of <em>Staphylococcus aureus</em>, 4 (16%) were methicillin resistant <em>Staphylococcus aureus</em> (MRSA).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas aeruginosa was the most common isolate, of which 28% were multi drug resistant. This calls for the judicious use of antibiotics and alternative measures for treatment of drug resistant strains. Formulating an antibiotic policy based on the local antibiogram can help in preventing the emergence and spread of resistant pathogens.</p>

2021 ◽  
Author(s):  
Ajay Kumar Chaurasiya ◽  
Rabindra Bhakta Pradhananga ◽  
Dipendra Kumar Mandal ◽  
Manoj Mahato ◽  
Niranjan Prasad Sah ◽  
...  

Abstract ObjectiveThis study was designed to find out the fungal aetiological agents in chronic suppurative otitis media (CSOM) patients attending tertiary care centre of Nepal. ResultTotal 123 samples of 117 patients, outdoor as well as indoor from Department of ENT and Head and Neck Surgery (HNS) TUTH, Maharajgunj, Kathmandu those specimens were processed and among them, 23(18.7%) was found potassium hydroxide (KOH) mount positive whereas positive growth was in 27 specimens. The prevalence rate of fungus was 21.95 percent in which the main pathogen was Aspergillus species (51.8%), followed by Candida species (14.8 %). Keywords: CSOM, KOH, Fungal culture, Aspergillus


Author(s):  
Abdul Rehman Khan ◽  
Farzana Siddiqui

<p class="abstract"><strong>Background:</strong> The aim of the study was to determine the incidence of different types of rhinosinusitis in patients attending ENT Department OPD at a tertiary care centre in Ruhelkhand area of Northern India.</p><p class="abstract"><strong>Methods:</strong> This study was done at department of Otorhinolaryngology, RMRI, Bareilly, India, a tertiary-care Teaching hospital. A total number of 39823 patients (22379 females, 17444 males) were included in this study from December 2017 till February 2020. Age range of selected patients was 3 months to 76 years, 3883 patients were having Rhinosinusitis and remaining having other ENT diseases.  </p><p class="abstract"><strong>Results:</strong> During 27 months period from December 2017 to February 2020, 39823 patients were seen in the OPD and patients were categorized in different disease groups, like chronic suppurative otitis media and acute suppurative otitis media, upper respiratory tract infections, acute and chronic tonsillitis and pharyngitis. Fourth most common disease group was different types of rhinosinusitis.</p><p class="abstract"><strong>Conclusions:</strong> In this study assessment was done of different ENT patients attending OPD. Chronic rhinosinusitis (46.1%) was the most common type of rhinosinusitis, followed by Acute type (29.7%).</p>


2012 ◽  
Vol 7 (2) ◽  
pp. 1-8 ◽  
Author(s):  
RK Sanjana ◽  
YI Singh ◽  
NS Reddy

The present study was carried out to determine the aerobic microorganisms involved and their antibiotic sensitivity pattern in patients with Chronic Suppurative Otitis Media (CSOM) and to provide a guideline for empirical antibiotic therapy.Between March 2009 to February 2011, the ear discharge samples submitted at the microbiology laboratory were processed aerobically and all the isolates were included in this study. All organisms were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern was determined by modified Kirby Bauer disc diffusion method as per National Committee for Clinical Laboratory Standard recommendations.Out of a total of 214 samples, microbiological culture was yielded from 202 (94.3%) specimens. Single organism were isolated from 168 (78.5%) of the culture positive specimens, while the remaining 34 (15.9%) had two or more organisms isolated. Pseudomonas aeruginosa 59 (35.1%) was the most common isolate, followed by Staphylococcus aureus 42 (25.0%) including 5 (3%) of the Methicillin Resistant Staphylococcus Aureus (MRSA). Antibiotic sensitivities of Pseudomonas aeruginosa showed that 93.2% isolates were sensitive to tobramycin, whereas, 91.5% isolates were sensitive to ceftazidime and 77.9% to amikacin.Only 50.8% of the isolates of Pseudomonas aeruginosa were sensitive to ciprofloxacin and 25.4% to gentamicin. For Staphylococcus aureus (other than MRSA) 95.2% were sensitive to cloxacillin, 83.3% to gentamicin and 78.5% to erythromycin. Only 07.1% were sensitive to ampicillin and 26.1% to ciprofloxacin.Pseudomonas aeruginosa was the most common isolate followed by Staphylococcus aureus. More than 90% of Pseudomonas and 90% of Staph aureus were sensitive to tobramycin and cloxacillin respectively. Therefore, these two drugs may be included in the formulary to cover the most common aerobic isolates involved in CSOM.Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-2, 1-8DOI: http://dx.doi.org/10.3126/jcmsn.v7i2.6673


Sign in / Sign up

Export Citation Format

Share Document