scholarly journals New technologies of hypotensive drug delivery in glaucoma treatment

2018 ◽  
Vol 11 (4) ◽  
pp. 103-107
Author(s):  
O. A. Kiseleva ◽  
A. M. Bessmertny ◽  
L. V. Yakubova

The paper reports on promising methods of drug delivery in glaucoma treatment: contact lenses, punctum plugs, intraocular implants, subconjunctival and supraciliary injections, ocular rings, hydrogels, nanocarriers.

Drug Delivery ◽  
2016 ◽  
Vol 23 (8) ◽  
pp. 3017-3026 ◽  
Author(s):  
Furqan A. Maulvi ◽  
Tejal G. Soni ◽  
Dinesh O. Shah

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Xiaohong Hu ◽  
Lingyun Hao ◽  
Huaiqing Wang ◽  
Xiaoli Yang ◽  
Guojun Zhang ◽  
...  

Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility and transparent characteristic. In order to increase the amount of load drug and to control their release at the expected intervals, many strategies are developed to modify the conventional contact lens as well as the novel hydrogel contact lenses that include (i) polymeric hydrogels with controlled hydrophilic/hydrophobic copolymer ratio; (ii) hydrogels for inclusion of drugs in a colloidal structure dispersed in the contact lenses; (iii) ligand-containing hydrogels; (iv) molecularly imprinted polymeric hydrogels; (v) hydrogel with the surface containing multilayer structure for drugs loading and releasing. The advantages and disadvantages of these strategies in modifying or designing hydrogel contact lenses for extended ophthalmic drug delivery are analyzed in this paper.


2019 ◽  
Vol 42 (2) ◽  
pp. 190-195 ◽  
Author(s):  
Heba Ghazal ◽  
Judy Ahmadouk ◽  
Sumayya Dhanji ◽  
Amani El-bushra ◽  
Reem Kayyali ◽  
...  

2018 ◽  
Vol 8 (5) ◽  
pp. 50-55 ◽  
Author(s):  
RD Rahane ◽  
Punit R. Rachh

The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. Formulation of a convenient dosage form for administration, by considering swallowing difficulty and poor patient compliance, leads to development of orally disintegrating tablets. Conventional preparation methods are spray drying, freeze drying, direct compression, Molding, and sublimation while new technologies have been developed for the production of orodispersible tablets. Keywords: Fast Dissolving Tablet, drug delivery system, fast disintegrating, fast melting.


2011 ◽  
Vol 7 (3) ◽  
pp. 1019-1030 ◽  
Author(s):  
Fernando Yañez ◽  
Lahja Martikainen ◽  
Mara E.M. Braga ◽  
Carmen Alvarez-Lorenzo ◽  
Angel Concheiro ◽  
...  

2018 ◽  
Vol 548 (1) ◽  
pp. 139-150 ◽  
Author(s):  
Furqan A. Maulvi ◽  
Sulabh S. Singhania ◽  
Ankita R. Desai ◽  
Manish R. Shukla ◽  
Aniruddha S. Tannk ◽  
...  

2018 ◽  
Vol 93 ◽  
pp. 36-48 ◽  
Author(s):  
Qiang Zhu ◽  
Yidan Wei ◽  
Conghao Li ◽  
Shirui Mao

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