scholarly journals In Vitro Inhibition Capacity in Ca Oxalate Formation by Lemon (Citrus Lemon) Juice

2015 ◽  
Vol 1 (2) ◽  
pp. 41
Author(s):  
Endang Tri Wahyuni Maharani ◽  
Jatmiko Susilo ◽  
Arifiani Agustin Amalia
Keyword(s):  
Citric Acid ◽  
Calcium Oxalate ◽  
Treatment Process ◽  
Lemon Juice ◽  
Optimum Concentration ◽  
Calcium Oxalate Crystal ◽  
Turbidity Level ◽  
In Vitro Inhibition ◽  
Ca Oxalate

<p style="text-align: justify;">This research aims to determine the inhibition capacity of lemon juice (Citrus lemon) in the formation of calcium oxalate in a variety of concentrations of 5%, 7.5%, 10% which is then compared to pure citric acid. Lemon juice contains citric acid that can inhibit calcium oxalate’s formation. Inhibitory activity found in lemon juice is examined by observing its inhibition capacity towards the formation of calcium oxalate crystal. At the end of the treatment process the turbidity level is compared to citric acid acting as an inhibitor in the formation of calcium oxalate and then the percentage of the inhibition capacity is calculated. Result of the study shows that the optimum concentration of the lemon juice (Citrus lemon) and citric acid is 10%. The inhibition capacities in calcium oxalate formation by lemon juice with concentration variations of 5%, 7.5%, 10% are 47.06%, 73.68%, 94.19% and by citric acid with concentration variations of 5%, 7.5 %, 10% are 29.90%, 30.85%, 42.30%. It can be concluded that the higher the concentration of lemon juice and citric acid used the higher the inhibition capacity of calcium oxalate. Based on the inhibition capacity percentage, lemon juice is more effective in inhibiting the formation of calcium oxalate compared to citric acid and it can function as an alternative to prevent the formation of kidney stone. © 2015 JNSMR UIN Walisongo. All rights reserved</p>

scholarly journals In Vitro Inhibition Capacity in Ca Oxalate Formation by Lemon (Citrus Lemon) Juice

2017 ◽  
Vol 1 (2) ◽  
pp. 41
Author(s):  
Endang Tri Wahyuni Maharani ◽  
Jatmiko Susilo ◽  
Arifiani Agustin Amalia
Keyword(s):  
Citric Acid ◽  
Calcium Oxalate ◽  
Treatment Process ◽  
Lemon Juice ◽  
Font Size ◽  
Calcium Oxalate Crystal ◽  
Turbidity Level ◽  
Normal Background ◽  
Ca Oxalate

<p style="margin: 0in 0in 0.0001pt; text-align: justify; line-height: normal; background: white; font-size: 11pt; font-family: Calibri, sans-serif;"><span style="font-size: 10.0pt; font-family: 'Cambria','serif'; color: black;">This research aims to determine the inhibition capacity of lemon juice (<em>Citrus lemon</em>) in the formation of calcium oxalate in a variety of concentrations of 5%, 7.5%, 10% which is then compared to pure citric acid. Lemon juice contains citric acid that can inhibit calcium oxalate’s formation. Inhibitory activity found in lemon juice is examined by observing its inhibition capacity towards the formation of calcium oxalate crystal. At the end of the treatment process the turbidity level is compared to citric acid acting as an inhibitor in the formation of calcium oxalate and then the percentage of the inhibition capacity is calculated. Result of the study shows that the optimum concentration of the lemon juice (<em>Citrus lemon</em>) and citric acid is 10%. The inhibition capacities in calcium oxalate formation by lemon juice with concentration variations of 5%, 7.5%, 10% are 47.06%, 73.68%, 94.19% and by citric acid with concentration variations of 5%, 7.5 %, 10% are 29.90%, 30.85%, 42.30%. It can be concluded that the higher the concentration of lemon juice and citric acid used the higher the inhibition capacity of calcium oxalate. Based on the inhibition capacity percentage, lemon juice is more effective in inhibiting the formation of calcium oxalate compared to citric acid and it can function as an alternative to prevent the formation of kidney stone.</span> <span style="font-size: 10.0pt; font-family: 'Cambria','serif'; color: black;">© 2015 JNSMR UIN Walisongo. All rights reserved.</span></p>

scholarly journals Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily.

1992 ◽  
Vol 89 (1) ◽  
pp. 426-430 ◽  
Author(s):  
H. Shiraga ◽  
W. Min ◽  
W. J. VanDusen ◽  
M. D. Clayman ◽  
D. Miner ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Calcium Oxalate ◽  
Aspartic Acid ◽  
Calcium Oxalate Crystal ◽  
Protein Superfamily

Magnesium Reduces Calcium Oxalate Crystal Formation in Human Whole Urine

1982 ◽  
Vol 62 (1) ◽  
pp. 17-19 ◽  
Author(s):  
P. C. Hallson ◽  
G. A. Rose ◽  
S. Sulaiman
Keyword(s):  
Calcium Oxalate ◽  
Inverse Correlation ◽  
Normal Volunteer ◽  
Urine Samples ◽  
Magnesium Concentration ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal ◽  
Isotopic Methods ◽  
Whole Urine

1. A low urinary magnesium was induced in normal volunteer subjects by giving cellulose phosphate; magnesium was added in vitro to yield urine samples of normal and high magnesium concentrations 2. After rapid evaporation of these urine samples at pH 5.3 to standard osmolality the calcium oxalate crystals were measured by microscopy and isotopic methods 3. There was a clear inverse correlation between magnesium concentration and calcium oxalate crystal formation 4. The case for treating calcium oxalate urolithiasis with magnesium is strengthened.

Evaluation of Antiurolithiatic activity of Polyherbal formulation (Lithout Tablets) by In-vitro inhibition of Calcium Oxalate Crystallization

2019 ◽  
Vol 12 (11) ◽  
pp. 5477
Author(s):  
Pradnya N. Jagtap ◽  
Bhagyashri R. Vyapari ◽  
Yashashri H. Nimbalkar ◽  
Sitaram V. Kale ◽  
Ganesh B. Nigade
Keyword(s):  
Calcium Oxalate ◽  
Calcium Oxalate Crystallization ◽  
Polyherbal Formulation ◽  
In Vitro Inhibition

Tamm-Horsfall Mucoprotein Reduces Promotion of Calcium Oxalate Crystal Aggregation Induced by Urate in Human Urine In Vitro

1994 ◽  
Vol 87 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Phulwinder K. Grover ◽  
Villis R. Marshall ◽  
Rosemary L. Ryall
Keyword(s):  
Calcium Oxalate ◽  
Stone Formation ◽  
Urine Samples ◽  
Urine Specimen ◽  
Calcium Oxalate Crystal ◽  
Physiological Concentration ◽  
Calcium Oxalate Crystallization ◽  
Crystal Aggregation

1. Increasing the concentration of dissolved urate promotes calcium oxalate crystallization in urine from which Tamm-Horsfall mucoprotein, an inhibitor of calcium oxalate crystal aggregation, has almost completely been removed. This study aimed to determine whether the effect of urate could be reduced or abolished by a physiological concentration of Tamm-Horsfall mucoprotein. This was approached in two ways. 2. The effect of Tamm-Horsfall mucoprotein on calcium oxalate crystallization induced by urate was tested in ultrafiltered (10 kDa) urine samples from 10 healthy men. Tamm-Horsfall mucoprotein (35 mg/l) was added to half of each specimen, the urate concentration was increased by the addition of sodium urate solution and crystallization was induced by a standard load of oxalate. The remainder of each urine specimen was used as a control; these specimens were treated with an identical amount of urate solution, but contained no Tamm-Horsfall mucoprotein. Tamm-Horsfall mucoprotein had no effect on the urinary metastable limit or on the deposition of calcium oxalate, but significantly reduced the size of the particles precipitated. 3. The effect of increasing the urate concentration in the presence of Tamm-Horsfall mucoprotein was tested. Tamm-Horsfall mucoprotein (35 mg/l) was added to 10 ultrafiltered urine samples as before, the samples were divided, and the concentration of urate was increased in half of each specimen. Compared with the control to which no urate was added, urate significantly reduced the amount of oxalate required to induce spontaneous calcium oxalate nucleation and increased the median volume and the particle size of the material deposited. 4. It was concluded that, in vivo, (a) hyperuricosuria would encourage the formation of calcium oxalate stones by promoting calcium oxalate crystallization, (b) Tamm-Horsfall mucoprotein would not lessen the effect of urate on calcium oxalate nucleation or bulk deposition but would reduce its effect on crystal aggregation; it could therefore reduce the likelihood of stone formation in patients with hyperuricosuria.

In vitro and clinical study of oxalate influence on calcium oxalate crystal formation

1988 ◽  
Vol 87 (4) ◽  
pp. 494-506 ◽  
Author(s):  
Y. Berland ◽  
M. Olmer ◽  
M. Grandvuillemin ◽  
H.E. Lundager Madsen ◽  
R. Boistelle
Keyword(s):  
Clinical Study ◽  
Calcium Oxalate ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal

In vitro inhibition and dissolution of calcium oxalate by edible plant Trianthema monogyna and pulse Macrotyloma uniflorum extracts

2005 ◽  
Vol 273 (3-4) ◽  
pp. 546-554 ◽  
Author(s):  
Ishwar Das ◽  
S.K. Gupta ◽  
Shoeb A. Ansari ◽  
V.N. Pandey ◽  
R.P. Rastogi
Keyword(s):  
Calcium Oxalate ◽  
Edible Plant ◽  
Macrotyloma Uniflorum ◽  
In Vitro Inhibition
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