scholarly journals Ultrasound and Infantile Pyloric Stenosis (IHPS) early Detection Better Patients

2016 ◽  
Vol 20 (3) ◽  
Author(s):  
Sajid Hameed Dar ◽  
Sarfraz Ahmed ◽  
Muhammad Afzal Sheikh
Keyword(s):  
Early Detection ◽  
Pyloric Stenosis ◽  
Early Treatment ◽  
Imaging Modality ◽  
Hypertrophic Pyloric Stenosis ◽  
Easy Access ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Salient Features ◽  
Infantile Pyloric Stenosis

The role of ultrasound in the diagnosis of Infantile Hypertrophic Pyloric Stenosis (IHPS) can not be over emphasized. The easy availability of this reliable imaging modality may contribute to prompter diagnosis and early treatment. The author wishes to present comparison of two series, of 52 patients each, conducted in the same department, but five years apart. Spread over more than a decade our experience with IHPS patients has undergone dramatic changes, especially the diagnostic part of it. Salient features of the two studies will be highlighted. In addition the study will examine whether the easy access to ultrasound has affected the care of infants with pyloric stenosis.

The role of nitric oxide synthase in infantile hypertrophic pyloric stenosis

2001 ◽  
Vol 77 (4) ◽  
pp. 307-12
Author(s):  
Irnak M. Barbosa ◽  
Saulo M.R. Ferrante ◽  
Carlos A. Mandarim-de-Lacerda
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Pyloric Stenosis ◽  
Hypertrophic Pyloric Stenosis ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Oxide Synthase

Neonatal Emergencies II: Infantile Hypertrophic Pyloric Stenosis & Intestinal Obstruction

2019 ◽  
Author(s):  
Iva Vassileva Vesselinova
Keyword(s):  
Pyloric Stenosis ◽  
Hypertrophic Pyloric Stenosis ◽  
Critical Factor ◽  
Anorectal Malformations ◽  
Duodenal Atresia ◽  
Medical Emergency ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Rapid Sequence ◽  
Intraoperative Management ◽  
Infantile Pyloric Stenosis

This review focuses on the clinical presentation, diagnosis, preoperative stabilization and intraoperative management of infantile hypertrophic pyloric stenosis (IHPS) and neonatal gastrointestinal obstructions. IHPS poses medical emergency, which demands adequate preoperative optimization of the intravascular status and metabolic derangements before proceeding with surgery. In contrast, malrotation and volvulus require immediate surgical exploration under ongoing aggressive resuscitation in order to minimize further deterioration and preserve bowel length. Congenital anomalies, associated with disorders such as duodenal atresia, malrotation, volvulus, and anorectal malformations, warrant focused examinations to characterize the defect and severity of functional impairment, but they should not delay interventions for which time is a critical factor. This review contains 2 tables, and 41 references. Key words: neonatal, infantile pyloric stenosis, gastrointestinal, vomiting, metabolic, resuscitation, obstruction, malformation, apnea, rapid sequence.    

scholarly journals Protocol: A systematic review and meta-analysis of the role of fetal and infantile environmental exposure in etiopathogenesis of infantile hypertrophic pyloric stenosis

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247003
Author(s):  
Ozlem Boybeyi-Turer ◽  
Hasan Tolga Çelik ◽  
Umut Ece Arslan ◽  
Tutku Soyer ◽  
Feridun Cahit Tanyel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Statistical Analysis ◽  
Pyloric Stenosis ◽  
Human Subjects ◽  
Meta Analysis ◽  
Hypertrophic Pyloric Stenosis ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Inclusion Criteria ◽  
Turkish Language

Infantile hypertrophic pyloric stenosis (IHPS) is one of the hallmark pediatric surgical diseases. However, its etiology remains incompletely understood. By systematically reviewing the literature, we aim to clarify the effect of the effect of occupational and environmental factors and role of nitric oxide (NO) metabolism in the etiopathogenesis of IHPS. The systematic review is drafted with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement (PRISMA) and the Meta-analysis of Observational Studies in Epidemiology (MOOSE). Systematic literature search will be performed for the period 2000 (Jan) to 2020 (Dec) in the databases: MEDLINE, EMBASE, PubMed. The systematic search will cover the literature in English and Turkish language and will be limited to studies on human subjects. Four investigators will independently search the databases (MEDLINE, EMBASE, PubMed) according to the defined search strategy. The full-text of the selected articles will be screened independently by four reviewers, against the inclusion criteria. Descriptive data will be extracted from each study regarding: study details, methods, participants, outcomes and calculations of association for potential further statistical analysis. If meta-analysis could not be undertaken, systematic approach to analyzing the findings of included multiple studies will be described. Heterogeneity will be assessed by quantifying the inconsistency across studies using I2 statistic. Statistical analysis will be performed using Comprehensive Meta-Analysis Version 3.0 software. The p values lower than 0.05 will be considered statistically significant for all analyses.

scholarly journals Role of Helicobacter pylori in the pathogenesis of infantile hypertrophic pyloric stenosis

2011 ◽  
Vol 8 (2) ◽  
pp. 172 ◽  
Author(s):  
Kamyar Ghabili ◽  
DevendraK Gupta ◽  
Saeid Aslanabadi ◽  
Diana Diaz ◽  
Mandana Rafeey ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Pyloric Stenosis ◽  
Hypertrophic Pyloric Stenosis ◽  
Infantile Hypertrophic Pyloric Stenosis

The Role of Ret Genomic Variants in Infantile Hypertrophic Pyloric Stenosis

2011 ◽  
Vol 21 (06) ◽  
pp. 389-394 ◽  
Author(s):  
A. Serra ◽  
K. Schuchardt ◽  
J. Genuneit ◽  
C. Leriche ◽  
H. Görgens ◽  
...  
Keyword(s):  
Pyloric Stenosis ◽  
Hypertrophic Pyloric Stenosis ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Genomic Variants

To Manage Infantile Hypertrophic Pyloric Stenosis by "Double-Y Pyloromyotomy" is a better Surgical Approach

2014 ◽  
Vol 1 (2) ◽  
pp. 143-147
Author(s):  
Md. Ansar Ali ◽  
Kaniz Hasina ◽  
Shahnoor Islam ◽  
Md. Ashraf Ul Huq ◽  
Md. Mahbub-Ul Alam ◽  
...  
Keyword(s):  
Weight Gain ◽  
Pyloric Stenosis ◽  
Hypertrophic Pyloric Stenosis ◽  
Treatment Modalities ◽  
Infantile Hypertrophic Pyloric Stenosis ◽  
Postoperative Vomiting ◽  
Acid Base ◽  
Feeding Regimes ◽  
Acid Base Status ◽  
Postoperative Feeding

Background: Different treatment modalities and procedures have been tried for the management of infantile hypertrophic pyloric stenosis. But surgery remains the mainstay for management of IHPS. Ramstedt’s pyloromyotomy was described almost over a hundred years ago and to date remains the surgical technique of choice. An alternative and better technique is the double-Y pyloromyotomy, which offer better results for management of this common condition.Methods: A prospective comparative interventional study of 40 patients with IHPS was carried out over a period of 2 years from July 2008 to July 2010. The patients were divided into 2 equal groups of 20 patients in each. The study was designed that all patients selected for study were optimized preoperatively regarding to hydration, acid-base status and electrolytes imbalance. All surgeries were performed after obtaining informed consent. Standard preoperative preparation and postoperative feeding regimes were used. The patients were operated on an alternate basis, i.e., one patient by Double-Y Pyloromyotomy(DY) and the next by aRamstedt’s Pyloromyotomy (RP). Data on patient demographics, operative time, anesthesia complications, postoperative complications including vomiting and weight gain were collected. Patients were followed up for a period of 3 months postoperatively. Statistical assessments were done by using t test.Results: From July 2008 through July 2010, fourty patients were finally analyzed for this study. Any statistical differences were observed in patient population regarding age, sex, weight at presentation, symptoms and clinical condition including electrolytes imbalance and acid-base status were recorded. Significant differences were found in postoperative vomiting and weight gain. Data of post operative vomiting and weight gain in both groups were collected. Vomiting in double-Y(DY) pyloromyotomy group (1.21 ± 0.45days) vs Ramstedt’s pyloromyotomy (RP) group(3.03 ± 0.37days) p= 0.0001.Weight gain after 1st 10 days DY vs RP is ( 298 ± 57.94 gm vs193±19.8 gm p=0.0014), after 1 month (676.67±149.84 gm vs 466.67 ± 127.71 gm, p=0.0001), after 2months (741.33± 278.74 gm vs 490±80.62 gm, p=0.002) and after 3 months (582±36.01gm vs 453.33±51.64 gm, p=0.0001).No long-term complications were reported and no re-do yloromyotomy was needed.Conclusion: The double-Y pyloromyotomy seems to be a better technique for the surgical management of IHPS. It may offer a better functional outcome in term of postoperative vomiting and weight gain.DOI: http://dx.doi.org/10.3329/jpsb.v1i2.19532

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