scholarly journals Hepatitis C Virus RNA and Anti-N14 Antibody Levels during Interferon Alpha Therapy for Chronic Hepatitis C.

1994 ◽  
Vol 33 (10) ◽  
pp. 588-592
Author(s):  
Makoto OKETANI ◽  
Keiichi TANAKA ◽  
Yukihiko SHO ◽  
Eiki MAEDA ◽  
Hiroomi MIYAZAKI ◽  
...  
1993 ◽  
Vol 32 (7) ◽  
pp. 523-529 ◽  
Author(s):  
Shozo WATANABE ◽  
Yoshinao KOBAYASHI ◽  
Masayoshi KONISHI ◽  
Masato YOKOI ◽  
Ryuichi KAKEHASHI ◽  
...  

2016 ◽  
Vol 10 (2) ◽  
pp. 417-422 ◽  
Author(s):  
Akira Sato ◽  
Toshiya Ishii ◽  
Kayo Adachi ◽  
Hideaki Takahashi ◽  
Fumiaki Sano ◽  
...  

Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment. We report a case of clearance of chronic hepatitis C virus infection following early discontinuation (at 6 weeks) of peginterferon plus ribavirin therapy, without negativity for hepatitis C virus RNA during the treatment period. The patient was a 76-year-old Japanese male infected with hepatitis C virus genotype 1b and TT of IL28B rs8099917. Hepatitis C virus RNA remained positive at persistently low levels for more than 2 months after the cessation of therapy and became negative at 7 months after the discontinuation of therapy. Spontaneous clearance of hepatitis C virus RNA can occur following antiviral failure in patients with persistently low viral loads, and virological follow-up is therefore necessary in chronic hepatitis C virus infection, even after antiviral failure.


Sign in / Sign up

Export Citation Format

Share Document