MOLECULAR BIOLOGY TOWARD MEDICAL SCIENCES

Introduction. The mechanism of how viruses cross intracellular structures is the model that exemplifies the intracellular transit through the endomembrane system, the same that is used in the teaching and description of the different intracellular apparatus and organelles. Objective. Develop a didactic method that explains a mechanism of molecular biology, such as the comic strip in the transit and intracellular signaling of viruses. Methodology. A comic-illustrative story was designed where a viral structure is personified by an undercover spy, the fundamental axis of the plot is obtaining the genetic information molecules at the nucleus level, for this it has to go through the various departments of the cell representing the intracellular and intracytoplasmic organelles with their functional characteristics, the sequence obeys the communication that the different organelles have from the cell membrane to the nucleus. Results. The development of comics or comics can recreate events and phenomena studied in medical sciences such as biology, having the following results: increase interest, understanding, creativity, the need for knowledge and generation of new ideas in students. Conclusion. The comic is a useful didactic tool in teaching intracellular transit from the graphic narration of a viral model that is transported inside the cell.

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Un cómic ilustrativo sobre el tránsito intracelular de los virus.

Revista Española de Educación Médica ◽

10.6018/edumed.491771 ◽

2021 ◽

Vol 2 (3) ◽

Author(s):

Juan Miguel Alemán-Iñiguez

Keyword(s):

Molecular Biology ◽

Cell Membrane ◽

Genetic Information ◽

Intracellular Signaling ◽

Comic Strip ◽

Endomembrane System ◽

Medical Sciences ◽

Viral Structure ◽

El Sistema ◽

New Ideas

El mecanismo de cómo los virus atraviesan las estructuras intracelulares son el modelo que ejemplifica el tránsito intracelular por el sistema de endomembranas, el mismo que es utilizado en la descripción de los diferentes aparatos intracelulares. El objetivo fue desarrollar un método didáctico que explique un mecanismo de la biología molecular, como lo es la tira cómica en el tránsito y la señalización intracelular de los virus. Se diseñó una historia cómica-ilustrativa donde una estructura viral es personificada por un espía encubierto, el eje fundamental de la trama es la obtención de las moléculas de información genética a nivel del núcleo, para ello tiene que pasar por los varios departamentos de la célula que representan las organelas intracitoplasmáticas con sus características funcionales, la secuencia obedece a la comunicación que tienen las diferentes organelas desde la membrana celular hasta el núcleo. La elaboración de comics o historietas pueden recrear eventos y fenómenos estudiados en las ciencias médicas como la biología, teniendo los siguientes resultados: aumentar el interés, la comprensión, la creatividad, la necesidad de conocimientos y generación de nuevas ideas en los estudiantes. El cómic es una herramienta didáctica útil en la enseñanza del tránsito intracelular a partir de la narración gráfica de un modelo viral que se transporta al interior de la célula. The mechanism of how viruses cross intracellular structures is the model that exemplifies intracellular transit through the endomembrane system, the same that is used in the description of the different intracellular apparatus. The objective was to develop a didactic method that explains a mechanism of molecular biology, such as the comic strip in the transit and intracellular signaling of viruses. A comic-illustrative story was designed where a viral structure is personified by an undercover spy, the fundamental axis of the plot is obtaining the genetic information molecules at the nucleus level, for this it has to go through the various departments of the cell that represent the intracytoplasmic organelles with their functional characteristics, the sequence obeys the communication that the different organelles have from the cell membrane to the nucleus. The development of comics or comics can recreate events and phenomena studied in medical sciences such as biology, having the following results: increase interest, understanding, creativity, the need for knowledge and generation of new ideas in students. The comic is a useful didactic tool in teaching intracellular transit from the graphic narration of a viral model that is transported inside the cell.

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Electron Microscopy in Molecular Biology

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100060027 ◽

1967 ◽

Vol 25 ◽

pp. 2-3

Author(s):

Cecil E. Hall

Keyword(s):

Electron Microscopy ◽

Molecular Biology ◽

Noise Level ◽

Molecular Structures ◽

Material Structure ◽

The Arts ◽

Shadow Casting ◽

Electron Image ◽

High Degree ◽

Very High

The visualization of organic macromolecules such as proteins, nucleic acids, viruses and virus components has reached its high degree of effectiveness owing to refinements and reliability of instruments and to the invention of methods for enhancing the structure of these materials within the electron image. The latter techniques have been most important because what can be seen depends upon the molecular and atomic character of the object as modified which is rarely evident in the pristine material. Structure may thus be displayed by the arts of positive and negative staining, shadow casting, replication and other techniques. Enhancement of contrast, which delineates bounds of isolated macromolecules has been effected progressively over the years as illustrated in Figs. 1, 2, 3 and 4 by these methods. We now look to the future wondering what other visions are waiting to be seen. The instrument designers will need to exact from the arts of fabrication the performance that theory has prescribed as well as methods for phase and interference contrast with explorations of the potentialities of very high and very low voltages. Chemistry must play an increasingly important part in future progress by providing specific stain molecules of high visibility, substrates of vanishing “noise” level and means for preservation of molecular structures that usually exist in a solvated condition.

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Molecular Biology and Biotechnology

10.1039/9781849730211 ◽

2009 ◽

Cited By ~ 4

Keyword(s):

Molecular Biology

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An introduction to the themed issue on RNA biology in China

Essays in Biochemistry ◽

10.1042/ebc20200031 ◽

2020 ◽

Vol 64 (6) ◽

pp. 863-866

Author(s):

Zhe Wu

Keyword(s):

Molecular Biology ◽

Chinese Society ◽

Fortieth Anniversary ◽

Rna Biology ◽

Research And Education ◽

Education In China

Abstract The year 2019 marked the fortieth anniversary of the Chinese Society of Biochemistry and Molecular Biology (CSBMB), whose mission is to promote biomolecular research and education in China. The last 40 years have witnessed tremendous growth and achievements in biomolecular research by Chinese scientists and Essays in Biochemistry is delighted to publish this themed issue that focuses on exciting areas within RNA biology, with each review contributed by key experts from China.

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