Microwave-Assisted Multicomponent Reactions in the Heterocyclic Chemistry

2010 ◽  
Vol 14 (4) ◽  
pp. 357-378 ◽  
Author(s):  
Bo Jiang ◽  
Feng Shi ◽  
Shu-Jiang Tu
2021 ◽  
Vol 17 ◽  
pp. 819-865
Author(s):  
Shivani Gulati ◽  
Stephy Elza John ◽  
Nagula Shankaraiah

Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged as one of the useful tools in the synthesis of biologically relevant heterocycles. These reactions are strategically employed for the generation of a variety of heterocycles along with multiple point diversifications. Over the last few decades classical MCRs such as Ugi, Biginelli, etc. have witnessed enhanced yield and efficiency with microwave assistance. The highlights of MWA-MCRs are high yields, reduced reaction time, selectivity, atom economy and simpler purification techniques, such an approach can accelerate the drug discovery process. The present review focuses on the recent advances in MWA-MCRs and their mechanistic insights over the past decade and shed light on its advantage over the conventional approach.


2013 ◽  
Vol 17 (5) ◽  
pp. 474-490 ◽  
Author(s):  
Amit Kumar Gupta ◽  
Neetu Singh ◽  
Krishna Nand Singh

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