An efficient and environmentally benign synthetic protocol has been developed for the synthesis of benzo[c]pyrazolo[2,7]naphthyridine derivatives through regioselective multi-component “on-water” reaction of isatin, malononitrile and 3-aminopyrazole.
Gold and silver nanoparticles were synthesized at room temperature using an aqueous extract from dried rosehips acting as reducing and capping agents with no other chemicals involved.