Relationship Between Atopic Dermatitis and Food Allergy

2020 ◽  
Vol 16 (2) ◽  
pp. 115-122
Author(s):  
Olga Domínguez ◽  
Ana María Plaza ◽  
Montserrat Alvaro

Consistent evidence has been found on the relationship between food allergy (FA) and atopic dermatitis (AD) in some children. Food sensitization can be often found in these patients. Allergy should be confirmed, though, with a food challenge test (FC) before advising a restrictive diet which could be harmful for the patient. Younger children with AD frequently show sensitization to egg, milk or peanut, while older ones and adults are more often sensitized to environmental allergens such as house dust mites, moulds, animal dander or pollens. It is well known that a barrier disturbance plays a main role in the development of sensitization and allergy. Therefore, due to the early appearance of AD, preventive newborn skincare with emollients and early introduction of food appear to be very important to determine food tolerance.

2020 ◽  
Vol 16 (2) ◽  
pp. 115-122
Author(s):  
Olga Domínguez ◽  
Ana María Plaza ◽  
Montserrat Alvaro

Consistent evidence has been found on the relationship between food allergy (FA) and atopic dermatitis (AD) in some children. Food sensitization can be often found in these patients. Allergy should be confirmed, though, with a food challenge test (FC) before advising a restrictive diet which could be harmful for the patient. Younger children with AD frequently show sensitization to egg, milk or peanut, while older ones and adults are more often sensitized to environmental allergens such as house dust mites, moulds, animal dander or pollens. It is well known that a barrier disturbance plays a main role in the development of sensitization and allergy. Therefore, due to the early appearance of AD, preventive newborn skincare with emollients and early introduction of food appear to be very important to determine food tolerance.


2015 ◽  
Vol 58 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Jarmila Čelakovská ◽  
Květuše Ettlerová ◽  
Karel Ettler ◽  
Josef Bukač

Background: A few reports demonstrate the occurrence of egg allergy in adolescent and adult patients suffering from atopic dermatitis and the association of this allergy to other food and aeroallergens. Aims and Objectives: The aim of this study is to evaluate the occurrence of egg allergy in patients suffering from atopic dermatitis at the age 14 years and older and to evaluate the relationship between egg allergy or egg sensitisation and the sensitisation to dust, mites, feather, and animal dander. Materials and Methods: Complete dermatological and allergological examination was performed. These parameters were examined: food allergy and food sensitisation to egg white and yolk, to mites, animal dander (mixture), feather and dust. The statistical evaluation of the relations among egg allergy, egg sensitisation and sensitisation to mites, animal dander (mixture), feather and dust was performed. Two hundred and eighty eight patients were included in the study (90 men, 198 women, with the average age 25.2). Results and Conclusion: Egg allergy was recorded in 5% and egg sensitisation in 20% of patients; sensitisation to dust is recorded more often in patients with positive results in sIgE for egg white and/or yolk.


2010 ◽  
Vol 7 (6) ◽  
pp. 60-63
Author(s):  
A N Pampura ◽  
E E Varlamov

Background. Establish indications for prescription of amino acid formula to infants with atopic dermatitis. Methods. 55 infants with atopic dermatitis and food allergy were enrolled. Allergic examination included skin prick tests and evaluation of specific IgE level. Oral challenge test was performed if necessary. Results. Low efficacy of elimination diet was observed in 16 infants with multiple food protein intolerance. In the issue cluster analysis defined two subgroups. High IgE levels, specific IgE to egg and fish were considered as criterions of the first subgroup. Patients with multiple food protein intolerance and low efficacy to elimination diet received amino acid formula, SCORAD index decreased more than 50% after the first week of treatment. Conclusion. Multiple food protein intolerance is particular form of food allergy. Prescription of amino acid formula is reasonable in this category of patients.


2011 ◽  
Vol 54 (4) ◽  
pp. 157-162 ◽  
Author(s):  
Jarmila Čelakovská ◽  
Květuše Ettlerová ◽  
Karel Ettler ◽  
Jaroslava Vaněčková ◽  
Josef Bukač

Few studies concerning the importance of wheat allergy affecting the course of atopic eczema in adolescents and adult patients exist. Aim: The evaluation if wheat allergy can deteriorate the course of atopic eczema. Follow-up of patients with confirmed food allergy to wheat. Method: Altogether 179 persons suffering from atopic eczema were included in the study: 51 men and 128 women entered the study with an average age of 26.2 (s.d. 9.5 years) Dermatological and allergological examinations were performed, including skin prick tests, atopy patch tests, and specific serum IgE for wheat, open exposure test and double-blind, placebo-controlled food challenge test with wheat flour. Results: Wheat allergy affecting the coures of atopic eczema was confirmed in eight patients (4.5%) out of 179 patients enrolled in this study by double-blind, placebo controlled food challenge test. The course of atopic eczema showed a positive trend in patients with confirmed food allergy at 3, 6, 9, 12 month follow-up (statistical evaluation with paired t-test) after the elimination of wheat flour. Conclusion: Wheat allergy may play an important role in the worsening of atopic eczema (acting as a triggering exacerbating factor) only in a minority of adolescents and adult patients (4.5% in our study). The diagnostic methods (skin prick test, specific IgE, atopy patch test, history) cannot be used as separated tests for the determination of food allergy to wheat in patients with atopic eczema.Open exposure tests and double-blind, placebo-controlled food challenge should be used for the confirmation of wheat allergy affecting the course of atopic eczema.


2010 ◽  
Vol 53 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Jarmila Čelakovská ◽  
Jaroslava Vaněčková ◽  
Květuše Ettlerová ◽  
Karel Ettler ◽  
Josef Bukač

Few studies concerning the importance of food allergy in adolescents and adult patients with atopic eczema exist. The atopy patch tests with food have mostly been studied in infants and children since food allergy plays a role especially in this age group. Aim: The evaluation of the contribution of atopy patch tests in the diagnostic work-up of food allergy (to wheat, cow milk, peanuts, soya and eggs) in the patients with atopic eczema older than 14 years of age. Method: 120 patients were examined in the study in the diagnostic work-up of food allergy – 86 women and 34 men, the mean age 26.5 (s.d. 9.8) and the median SCORAD at the beginning of the study 32.9 (s.d. 14.0). Complete dermatological and allergological examinations in the diagnostic work-up of food allergy were performed (assessment of personal history, assessment of serum specific IgE, skin prick tests, atopy patch tests, diagnostic hypoallergenic diet, food challenge tests with egg, soy, wheat, cow milk and double – blind, placebo – controlled food challenge test with cow milk and wheat. The results of atopy patch tests were compared with the results of other diagnostic methods in the diagnosis of food allergy. Results: The food allergy to cow milk and wheat was confirmed in double – blind, placebo controlled food challenge test in few patients in our study (4 %). The suspicion of food allergy to egg is in 8 %, to peanuts in 13 % and to soya in 4 % of patients in our study. The assessment of atopy patch tests response seems to be of great importance. The reaction in atopy patch tests with more papules has the greatest diagnostic accuracy for predicting the result of challenge tests. At the beginning and at the end of diagnostic hypoallergenic diet the severity of atopic eczema/dermatitis syndrome was recorded in all patients enrolled in the study by evaluating SCORAD. The decrease of SCORAD was statistically important. Conclusion: Atopy patch tests alone cannot be used as a single test for the determination of food allergy in patients with atopic eczema/dermatitis syndrome but such a test, together with other diagnostic methods, can help to trace the food allergy.


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