scholarly journals FEATURES OF DIET THERAPY IN INFANTS WITH POLYVALENTFOOD ALLERGY

2010 ◽  
Vol 7 (6) ◽  
pp. 60-63
Author(s):  
A N Pampura ◽  
E E Varlamov
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Challenge Test ◽  
Specific Ige ◽  
Elimination Diet ◽  
Food Protein ◽  
Oral Challenge Test ◽  
Protein Intolerance ◽  
Amino Acid Formula

Background. Establish indications for prescription of amino acid formula to infants with atopic dermatitis. Methods. 55 infants with atopic dermatitis and food allergy were enrolled. Allergic examination included skin prick tests and evaluation of specific IgE level. Oral challenge test was performed if necessary. Results. Low efficacy of elimination diet was observed in 16 infants with multiple food protein intolerance. In the issue cluster analysis defined two subgroups. High IgE levels, specific IgE to egg and fish were considered as criterions of the first subgroup. Patients with multiple food protein intolerance and low efficacy to elimination diet received amino acid formula, SCORAD index decreased more than 50% after the first week of treatment. Conclusion. Multiple food protein intolerance is particular form of food allergy. Prescription of amino acid formula is reasonable in this category of patients.

scholarly journals FEATURES OF THE CYTOKINE PROFILE IN INFANTS WITH MULTIPLE FOOD PROTEIN INTOLERANCE

2012 ◽  
Vol 9 (5) ◽  
pp. 76-80
Author(s):  
E E Varlamov ◽  
T V Vinogradova ◽  
A A Chuslyaeva ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Inflammatory Process ◽  
Allergic Diseases ◽  
Cytokine Profile ◽  
Food Protein ◽  
Additional Indication ◽  
Protein Intolerance

Introduction. Types of the course of allergic diseases may be related to cytokine profile. Determination of the spectrum of cytokines to evaluate the mechanisms of allergic inflammatory process that improves the efficiency of management of patients with allergic diseases was performed. Background. To establish the features of cytokine profile in children with multiple food protein intolerance. Methods. 39 children with atopic dermatitis and food allergy were included in the openlabel study, 18 of whom had multiple food protein intolerance. All patients were examined with enzyme immunoassay (ELISA) to determine the concentration of IL-4, IL-5, IL-13, IL-17, IL-22, eotaxin, eotaxin2, TGF-β. Results. In children with multiple food protein intolerance the concentration of TGF-β was increased in comparison with the group of children without multiple food intolerances Me 14,04 [11,3; 18,0] against 10,3 [4,8; 12, 8] pg/ml, respectively, p = 0,038. The level of other cytokines had no difference. Conclusion. Increased concentration of TGF-β in patients with multiple food protein intolerance may be an additional indication for the amino acid formulas.

scholarly journals Clinical and immunological characteristics ofpatients with polyvalent food allergy in reasoning of clinical prescribing of amino acid formula

2012 ◽  
Vol 9 (1) ◽  
pp. 84-87
Author(s):  
E E Varlamov ◽  
T S Okuneva ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Fruits And Vegetables ◽  
Specific Ige ◽  
Food Intolerance ◽  
Cow Milk ◽  
Amino Acid Formula

Methods: 117 infants with atopic dermatitis and food allergy were enrolled. The analysis of clinical and immunological characteristics of the infants with multiple food intolerance was performed. Results: asthma, high levels of specific IgE to cow milk, egg, beef, pork, sensitization to allergens of cereals, fruits and vegetables were characterized for infants with multiple food intolerance. Conclusion: infants with multiple food intolerance possess defined clinical and immunological characteristics which can form the basis for prescribing of amino acid formula.

scholarly journals DIET THERAPY IN CHILDREN WITH FOOD ALLERGY

2013 ◽  
Vol 10 (5) ◽  
pp. 70-75
Author(s):  
E E Varlamov ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Diet Therapy ◽  
Average Value ◽  
Multiple Food Allergy ◽  
Amino Acid Formula

Introduction. Experience of amino acid formulas application in eldest children is limited. Background. To estimate efficiency of amino acid formula at children at the age from 1 till 10 years with atopic dermatitis (AD). Methods. 9 AD children with multiple food allergy were included in the study. All patients took amino acid formula «Neocate Advance». The efficiency of diet therapy was estimated with index SCORAD. Results. The average value of index SCORAD decreased AFTER 1 week therapy, Me — 48,5 [44,5; 52,5] to Me — 18,8 [18; 37,5] a point (p=0,008), after 2 weeks — Me — 12,6 [7,8; 13,5] a point (p=0,008). Conclusion. Medical amino acid formula «Neocate Advance» is an effective diet therapy of AD children with multiple food allergy.

scholarly journals Severe atopic dermatitis in a boy with potato allergy

2020 ◽  
Vol 16 (3) ◽  
pp. 301-305
Author(s):  
Jędrzej Przekora ◽  
◽  
Agata Wawrzyniak ◽  
Anna Bujnowska ◽  
Agnieszka Rustecka ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Dietary Intervention ◽  
Paediatric Population ◽  
Specific Ige ◽  
Primary Treatment ◽  
Elimination Diet ◽  
Severe Form ◽  
Severe Atopic Dermatitis ◽  
Skin Prick Tests

Food allergy is an important problem in the paediatric population. Food products that are most likely to induce allergic reactions include cow’s milk, wheat, peanuts, hen’s eggs, fish and seafood. Food-allergy-related diseases include, among other things, atopic dermatitis, urticaria and asthma. Anaphylactic shock is the most severe form of allergic reaction. Intramuscular adrenalin at a dose of 0.01 mg/kg body weight (maximum dose 0.3–0.5 mg) is the primary treatment for anaphylaxis. An elimination diet is the treatment of choice in food allergy. If symptoms persist despite dietary intervention, extended diagnosis using skin prick tests and/or specific IgE measurements should be performed. We present a clinical case of a 2.5-year-old boy with erythroderma secondary to atopic dermatitis, who was referred to our Department due to the lack of improvement after outpatient treatment. It was found during hospital stay that the symptoms were caused by potato allergens.

scholarly journals Unexpected Cat Allergy in Infants with Persistent Atopic Dermatitis

2021 ◽  
Author(s):  
Serdar Al ◽  
Suna Asilsoy ◽  
Özden Anal ◽  
Dilek Tezcan ◽  
Seda Şirin Köse ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Elimination Diet ◽  
Severe Atopic Dermatitis ◽  
Barrier Dysfunction ◽  
Prick Test ◽  
Cat Allergy ◽  
History Of

Atopic dermatitis is a chronic, recurrent inflammatory skin disease usually caused by genetic predisposition, immune dysregulation, epidermal barrier dysfunction and interaction of environmental factors. Atopic dermatitis is part of atopic march and is often accompanied by food allergy. Aeroallergenic sensitization at early age is not an expected finding. Here, we present five cases with moderate-severe atopic dermatitis during infancy, in whom food allergy was detected and the symptoms improved only partially despite elimination and treatment. Sensitization was investigated in patients with a history of intense exposure to cats by specific IgE and skin prick test in infants with atopic dermatitis who had food allergy and persistant findings. Egg allergy was detected in four of the cases, wheat allergy in one. Cat allergy was present in all. Elimination diet was started in all cases. When exposure to cats was reduced, a marked improvement in the findings of atopic dermatitis was observed in all cases. Allergic diseases are increasing day by day. Unexpected aeroallergenic sensitization is now more common in the early stages of life. Allergic patients, regardless of age, should be questioned in detail for aeroallergen exposure. If it is detected; necessary preventive measures should be taken.

Relationship Between Atopic Dermatitis and Food Allergy

2020 ◽  
Vol 16 (2) ◽  
pp. 115-122
Author(s):  
Olga Domínguez ◽  
Ana María Plaza ◽  
Montserrat Alvaro
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Challenge Test ◽  
Food Challenge ◽  
House Dust Mites ◽  
Main Role ◽  
Early Introduction ◽  
Animal Dander ◽  
Restrictive Diet ◽  
The Relationship

Consistent evidence has been found on the relationship between food allergy (FA) and atopic dermatitis (AD) in some children. Food sensitization can be often found in these patients. Allergy should be confirmed, though, with a food challenge test (FC) before advising a restrictive diet which could be harmful for the patient. Younger children with AD frequently show sensitization to egg, milk or peanut, while older ones and adults are more often sensitized to environmental allergens such as house dust mites, moulds, animal dander or pollens. It is well known that a barrier disturbance plays a main role in the development of sensitization and allergy. Therefore, due to the early appearance of AD, preventive newborn skincare with emollients and early introduction of food appear to be very important to determine food tolerance.

scholarly journals FPIES in exclusively breastfed infants: two case reports and review of the literature

2020 ◽  
Vol 46 (1) ◽  
Author(s):  
Francesco Baldo ◽  
Martina Bevacqua ◽  
Cristiana Corrado ◽  
Daniela Nisticò ◽  
Laura Cesca ◽  
...  
Keyword(s):  
Amino Acid ◽  
Medical Literature ◽  
Challenge Test ◽  
Cow’S Milk ◽  
Diagnostic Process ◽  
Food Protein ◽  
Maternal Milk ◽  
Cow's Milk ◽  
Breastfed Infants ◽  
History Of

Abstract Background Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non IgE-mediated food allergy that generally affects children in the first year of life. Usually symptoms break out when formula milk or solid foods are introduced for the first time but they might also appear in exclusively breastfed infants, since the trigger elements, especially cow’s milk proteins, can be conveyed by maternal milk as well. FPIES in exclusively breastfed babies is a very rare clinical condition and only few cases have been reported in the medical literature. Case presentation We describe two cases of FPIES in exclusively breastfed babies. The first one is a two-month-old infant with a brief history of vomit and diarrhea that presented to the Emergency Department in septic-like conditions. The main laboratory finding was a significant increase in methemoglobin (13%). Clinically, we noted that, when breastfeeding was suspended, diarrhea drastically improved, and vice versa when maternal milk was reintroduced. An amino acid-based formula allowed a complete normalization of the symptoms. The second one is a three-month-old infant admitted for a 3 days history of persistent vomit and diarrhea. Blood tests showed a raised level of methemoglobin (7%). An esophagogastroduodenoscopy was performed and biopsies showed an eosinophilic infiltration of the duodenal mucosa. A maternal exclusion diet and an amino acid-based formula allowed a rapid regularization of the bowel function. Conclusions We searched all the cases of FPIES in exclusively breastfed babies reported in the medical literature, identifying eight patients, with an average age of 3 months (range 15 days – 6 months). The majority of the cases were initially diagnosed as gastroenteritis or sepsis, five cases were characterized by an acute on chronic scenario and cow’s milk was the most frequently involved food. Methemoglobin was never tested. An oral food challenge test was performed in two patients. FPIES in exclusively breastfed infants is a rare condition that, in the presence of compatible history and symptoms, should be considered also in exclusively breastfed babies. The evaluation of methemoglobin can simplify the diagnostic process.

Skin Manifestations of Food Allergy

PEDIATRICS ◽  
2003 ◽  
Vol 111 (Supplement_3) ◽  
pp. 1617-1624 ◽  
Author(s):  
Wesley Burks
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Specific Ige ◽  
Rational Approach ◽  
Severe Atopic Dermatitis ◽  
Acute Urticaria ◽  
Skin Response ◽  
Allergic Skin ◽  
Food Challenges ◽  
Food Specific Ige

The pediatrician is faced with evaluating a panoply of skin rashes, a subset of which may be induced by food allergy. Acute urticaria is a common manifestation of an allergic skin response to food, but food is rarely a cause of chronic urticaria. Approximately one third of infants/children with moderate to severe atopic dermatitis have food allergy. Although diagnosis of acute urticaria provoked by a food may be evident from a straightforward history and confirmed by diagnostic tests to detect food-specific IgE antibody, determination of the role of food allergy in patients with atopic dermatitis is more difficult and may require additional diagnostic maneuvers, including elimination diets and oral food challenges. The immunopathologic basis of food-allergic disorders that affect the skin and a rational approach to diagnosis and treatment are discussed. Additional disorders that are caused by or mimic ones caused by food allergy are reviewed.

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