Chemistry of Small Molecule Inhibitors in Self-Assembly of Alzheimers Disease Related Amyloid-Beta Peptide

2008 ◽  
Vol 4 (3) ◽  
pp. 159-174 ◽  
Author(s):  
Bela Torok ◽  
Sujaya Dasgupta ◽  
Marianna Torok
Keyword(s):  
Small Molecule ◽  
Amyloid Beta ◽  
Self Assembly ◽  
Small Molecule Inhibitors ◽  
Amyloid Beta Peptide ◽  
Alzheimers Disease ◽  
Beta Peptide

Wnt Signalling is a Relevant Pathway Contributing to Amyloid Beta-Peptide-Mediated Neuropathology in Alzheimers Disease

2010 ◽  
Vol 9 (6) ◽  
pp. 720-726 ◽  
Author(s):  
Odete A.B. da Cruz e Silva ◽  
Ana Gabriela Henriques ◽  
Sara Catarina Timoteo Santos Domingues ◽  
Edgar F. da Cruz e Silva
Keyword(s):  
Amyloid Beta ◽  
Wnt Signalling ◽  
Amyloid Beta Peptide ◽  
Alzheimers Disease ◽  
Beta Peptide

scholarly journals Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
V. Castelletto ◽  
P. Ryumin ◽  
R. Cramer ◽  
I. W. Hamley ◽  
M. Taylor ◽  
...  
Keyword(s):  
Amyloid Beta ◽  
Self Assembly ◽  
Amyloid Beta Peptide ◽  
Cytotoxicity Activity ◽  
Beta Peptide ◽  
Peptide Derivatives

Influence of the Solvent on the Self-Assembly of a Modified Amyloid Beta Peptide Fragment. I. Morphological Investigation

2009 ◽  
Vol 113 (29) ◽  
pp. 9978-9987 ◽  
Author(s):  
V. Castelletto ◽  
I. W. Hamley ◽  
P. J. F. Harris ◽  
U. Olsson ◽  
N. Spencer
Keyword(s):  
Amyloid Beta ◽  
Self Assembly ◽  
The Self ◽  
Amyloid Beta Peptide ◽  
Peptide Fragment ◽  
Morphological Investigation ◽  
Beta Peptide

scholarly journals Mercury and Alzheimers Disease: HG(II) Ions Display Specific Binding to the Amyloid-Beta Peptide and Modulate its Aggregation

2018 ◽  
Vol 114 (3) ◽  
pp. 219a ◽  
Author(s):  
Sebastian Warmlander ◽  
Cecilia Wallin ◽  
Sabrina Sholts ◽  
Per Roos ◽  
Jyri Jarvet ◽  
...  
Keyword(s):  
Amyloid Beta ◽  
Specific Binding ◽  
Amyloid Beta Peptide ◽  
Alzheimers Disease ◽  
Beta Peptide

Self-assembly characteristics of a structural analogue of Tjernberg peptide

RSC Advances ◽  
2014 ◽  
Vol 4 (32) ◽  
pp. 16517-16523 ◽  
Author(s):  
Keerthana Ramaswamy ◽  
Priyadharshini Kumaraswamy ◽  
Swaminathan Sethuraman ◽  
Uma Maheswari Krishnan
Keyword(s):  
Amyloid Beta ◽  
Self Assembly ◽  
Amyloid Plaques ◽  
Amyloid Beta Peptide ◽  
Side Chains ◽  
Structural Analogue ◽  
Beta Peptide

This article aims to understand the pathogenesis behind the formation of amyloid plaques using a modified version of the KLVFF peptide. It was found that the cytotoxicity of the nanostructures formed by the RIVFF peptide may be attributed to the aminoacids with long side chains along with hydrophobic aminoacids resembling the amyloid beta peptide.

Self-assembly in aqueous solution of a modified amyloid beta peptide fragment

2008 ◽  
Vol 138 (1-2) ◽  
pp. 29-35 ◽  
Author(s):  
V. Castelletto ◽  
I.W. Hamley ◽  
P.J.F. Harris
Keyword(s):  
Aqueous Solution ◽  
Amyloid Beta ◽  
Self Assembly ◽  
Amyloid Beta Peptide ◽  
Peptide Fragment ◽  
Beta Peptide
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