Quality of Life in People with Coeliac Disease: Psychological and Socio- Economic Aspects

Background and Objective: Coeliac disease (CD) is a chronic autoimmune intestinal disorder characterized by intolerance to gluten, a protein contained in certain cereals. The main physiopathological basis of CD is the progressive destruction of intestinal villi caused by gluten ingestion by genetically-susceptible individuals. Patients who receive a diagnosis of CD must make significant changes to their daily habits and this can affect their quality of life. The objective of this review is to summarize the evidence regarding the economic, physical and social limitations which can affect the quality of life in patients with CD. Results: Different factors such as physical changes, psychological effects, interpersonal relationships, emotions and economic difficulties can affect the quality of life of these patients. Observations suggest that, in general, women with CD experience a greater deterioration in their quality of life than men. Lastly, complications in daily life are also associated with the reduced availability of gluten-free products which also usually cost more than standard products. </P><P> Conclusions: Continuous health education and care regarding socio-economic issues should be continuously developed and provided to people with CD.

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The impact of symptoms on quality of life before and after diagnosis of coeliac disease: the results from a Polish population survey and comparison with the results from the United Kingdom

BMC Gastroenterology ◽

10.1186/s12876-021-01673-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Emilia Majsiak ◽

Magdalena Choina ◽

Dominik Golicki ◽

Alastair M. Gray ◽

Bożena Cukrowska

Keyword(s):

Quality Of Life ◽

United Kingdom ◽

Coeliac Disease ◽

Gluten Free Diet ◽

Gluten Free ◽

The United Kingdom ◽

Before And After ◽

The Mean ◽

The Uk

Abstract Background Coeliac disease (CD) is characterised by diverse clinical symptoms, which may cause diagnostic problems and reduce the patients’ quality of life. A study conducted in the United Kingdom (UK) revealed that the mean time between the onset of coeliac symptoms and being diagnosed was above 13 years. This study aimed to analyse the diagnostic process of CD in Poland and evaluate the quality of life of patients before and after CD diagnosis. In addition, results were compared to the results of the original study conducted in the UK. Methods The study included 2500 members of the Polish Coeliac Society. The patients were asked to complete a questionnaire containing questions on socio-demographic factors, clinical aspects and quality of life, using the EQ-5D questionnaire. Questionnaires received from 796 respondents were included in the final analysis. Results The most common symptoms reported by respondents were bloating (75%), abdominal pain (72%), chronic fatigue (63%) and anaemia (58%). Anaemia was the most persistent symptom, with mean duration prior to CD diagnosis of 9.2 years, whereas diarrhoea was observed for the shortest period (4.7 years). The mean duration of any symptom before CD diagnosis was 7.3 years, compared to 13.2 years in the UK. CD diagnosis and the introduction of a gluten-free diet substantially improved the quality of life in each of the five EQ-5D-5L health dimensions: pain and discomfort, anxiety and depression, usual activities, self-care and mobility (p < 0.001), the EQ-Index by 0.149 (SD 0.23) and the EQ-VAS by 30.4 (SD 28.3) points. Conclusions Duration of symptoms prior to the diagnosis of CD in Poland, although shorter than in the UK, was long with an average of 7.3 years from first CD symptoms. Faster CD diagnosis after the onset of symptoms in Polish respondents may be related to a higher percentage of children in the Polish sample. Introduction of a gluten-free diet improves coeliac patients’ quality of life. These results suggest that doctors should be made more aware of CD and its symptoms across all age groups.

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Coeliac disease and the gluten-free diet: a review of the burdens; factors associated with adherence and impact on health-related quality of life, with specific focus on adolescence

Journal of Human Nutrition and Dietetics ◽

10.1111/jhn.12375 ◽

2016 ◽

Vol 29 (5) ◽

pp. 593-606 ◽

Cited By ~ 51

Author(s):

L. E. White ◽

E. Bannerman ◽

P. M. Gillett

Keyword(s):

Quality Of Life ◽

Coeliac Disease ◽

Gluten Free Diet ◽

Gluten Free ◽

Health Related Quality ◽

Factors Associated ◽

Specific Focus ◽

Related Quality ◽

Health Related

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Effectiveness of nutritional supplementation for children with coeliac disease who are on a gluten-free diet

Medical Council ◽

10.21518/2079-701x-2019-17-138-146 ◽

2019 ◽

pp. 138-146

Author(s):

V. A. Kur’yaninova ◽

M. V. Stoyan ◽

I. N. Zakharova ◽

L. Ya. Klimov ◽

V. S. Kashnikov ◽

...

Keyword(s):

Quality Of Life ◽

Coeliac Disease ◽

Physical Development ◽

Nutritional Supplementation ◽

Gluten Free Diet ◽

Gluten Free ◽

Nutrient Deficiencies ◽

Quality Of Life Indicators ◽

Enteric Nutrition

Patients on a gluten-free diet are at risk of developing polyhypoavitaminosis and deficiency states, which requires the supplementation of their diet to prevent nutrient deficiencies. The aim of the study: to analyze the dynamics of anthropometric and laboratory parameters, components of the quality of life in children with coeliac disease on the background of a month-long course of administration of hypercaloric mixture for enteric nutrition. Materials and methods: 45 children with coeliac disease aged 2-10 years (mean age 6.3 ± 0.3 years) on a strict gluten-free diet for more than one year. All patients received additional enteric nutrition with a hypercaloric mixture in the volume of 200 ml/day (300 kcal/day) for 1 month as a supplement to the main food ration. Two groups of patients receiving the supplement in 2012-2013 and 2017-2018 were identified. Physical development was assessed under the WHO AnthroPlus programme. The quality of life indicators were assessed using the PedQL 4.0 questionnaire. Results: the total frequency of protein-сalorie deficiency (PCD) before the course of nutritional supplementation was 13 (28.9%) cases, while acute PCD was diagnosed in 6 (13.3%) and chronic PCD in 7 (15.6%) patients. Against the background of the course of nutritious supplementation in children with coeliac disease, there was a significant reduction in weight, height and BMI in both groups. Patients in 2012-2013 initially had a greater gap in weight and height compared to children in 2017-2018. There was an improvement in the sum of the quality of life indicators by 6.3% for children in the first group and by 4.3% for children in the second group against the background of nutritional supplementation. Conclusions: Enrichment of children’s diets with a hypercaloric blend of dietary fiber helps to accelerate the pace of physical development, reduce the number of children with diabetes mellitus, improve hemogram rates and most components of quality of life.

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Evaluation of the quality of life by means of WHOQOL-BREF questionnaire among people with coeliac disease, allergy and oversensitivity to gluten who follow the gluten-free diet

Medycyna Ogólna i Nauki o Zdrowiu ◽

10.5604/20834543.1124650 ◽

2014 ◽

Vol 20 (3) ◽

pp. 241-244

Author(s):

Anna Brończyk-Puzoń ◽

Joanna Bieniek ◽

Aneta Koszowska ◽

Justyna Nowak ◽

Anna Dittfeld ◽

...

Keyword(s):

Quality Of Life ◽

Coeliac Disease ◽

Gluten Free Diet ◽

Gluten Free

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A possible role for ghrelin, leptin, brain-derived neurotrophic factor and docosahexaenoic acid in reducing the quality of life of coeliac disease patients following a gluten-free diet

European Journal of Nutrition ◽

10.1007/s00394-015-1128-2 ◽

2015 ◽

Vol 56 (2) ◽

pp. 807-818 ◽

Cited By ~ 11

Author(s):

Francesco Russo ◽

Guglielmina Chimienti ◽

Caterina Clemente ◽

Carla Ferreri ◽

Antonella Orlando ◽

...

Keyword(s):

Quality Of Life ◽

Docosahexaenoic Acid ◽

Coeliac Disease ◽

Neurotrophic Factor ◽

Brain Derived Neurotrophic Factor ◽

Gluten Free Diet ◽

Gluten Free

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Diminished quality of life among adolescents with coeliac disease using maladaptive eating behaviours to manage a gluten‐free diet: a cross‐sectional, mixed‐methods study

Journal of Human Nutrition and Dietetics ◽

10.1111/jhn.12638 ◽

2019 ◽

Vol 32 (3) ◽

pp. 311-320 ◽

Cited By ~ 7

Author(s):

J. W. Cadenhead ◽

R. L. Wolf ◽

B. Lebwohl ◽

A. R. Lee ◽

P. Zybert ◽

...

Keyword(s):

Quality Of Life ◽

Mixed Methods ◽

Coeliac Disease ◽

Mixed Methods Study ◽

Gluten Free Diet ◽

Gluten Free ◽

Eating Behaviours ◽

Cross Sectional ◽

Maladaptive Eating

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The Amount of Water and Flour Particles Size Role in Gluten-Free Bread Production and Quality Evaluation

Journal of Food Studies ◽

10.5296/jfs.v8i1.14040 ◽

2018 ◽

Vol 8 (1) ◽

pp. 1 ◽

Cited By ~ 1

Author(s):

Vikendra Dabash ◽

Iva Buresova ◽

Richardos Nikolaos Salek

Keyword(s):

Coeliac Disease ◽

Water Volume ◽

Gluten Free ◽

Free Products ◽

Baking Process ◽

Different Types ◽

Single Use ◽

Bread Production ◽

Day By Day

Gluten-free products’ market is increasing day by day. Keeping to improved indicative methods, many people are recognized who are suffering with coeliac disease. Presently, the gluten-free foodstuffs which is safe for consumable for coeliac disease people, the market is growing rapidly. By using different types of cereals and flours makes it important to discover the other possibilities to take over the chore of gluten by other flour or flour components, by the increase of different components by substituting the various flours and baking process alteration. By the drive of this review, the author is to explain a summary of the water volume which used in the manufacturing of gluten-free bread and quality, to raise the manufacturing quality of gluten-free bread have already recorded procedure and ingredients in a single use assistance. The aim and goal of this review article is importance of water in gluten free bread baking.

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