scholarly journals Characterization of Patients with Difficult-to-Treat Acute Pain Following Total Knee Arthroplasty Using Multi-Modal Analgesia

2013 ◽  
Vol 6 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Syed A. Azim ◽  
Rebecca Sangster ◽  
Christine Curcio ◽  
Dominick Coleman ◽  
Usman Shah ◽  
...  

Objective: To determine the efficacy of post-operative pain control over the first 24 hours in patients undergoing unilateral total knee arthroplasty (TKA) using a multi-modal analgesia protocol including femoral nerve catheters (FNC). Materials and Methods: 119 patients who underwent unilateral TKA between 2009 and 2010 under regional anesthesia with FNC were studied. Electronic charts were reviewed for numerical rating scale (NRS) pain scores at baseline, from the time the patients entered the post-operative care unit and every 4 hours thereafter until FNC was discontinued at 24 hours post-surgery. Opioid usage was also recorded during the same time period. Results: Analysis of average NRS pain scores from all patients demonstrated that 69% had NRS pain scores ≤ 5 (‘low pain’ (LP) group) and 31% had NRS pain scores ≥ 6 (‘high pain’ (HP) group). Time analysis showed that HP patients' high pain scores persisted for 24 hours post-surgery and they were characterized by being younger when compared to the LP patients.The majority of HP patients were female. Further analysis demonstrated that the average body mass index (BMI) of the female HP patients was significantly greater than females with LP. Conclusions: In spite of a diverse multi-modal analgesia protocol designed for TKA surgery, 31% of our patients had ‘difficult-to-treat’ pain (NRS pain scores ≥ 6) for 24hours postsurgery. Our analysis implicates age, pre-operative pain scores, female gender and obesity as potential risk factors for experiencing insufficient pain control with the currently evaluated multimodal pain protocol post-TKA surgery.

2020 ◽  
Vol 23 (03) ◽  
pp. 2050006
Author(s):  
Mahmoud Fahmy

Purpose: Evaluate the reliability of the early functional recovery and postoperative pain control using adductor canal block (ACB) compared with that using femoral nerve block (FNB) in patients undergoing total knee replacement (TKR). Patients and Methods: A total of 80 patients scheduled for TKR were randomly and blindly distributed into two groups (40 patients each). Group A received ACB and group F received FNB. The early quadriceps strength, range of motion and pain control were assessed after surgery during the first 48[Formula: see text]h. Results: Patients in group F had significantly less quadriceps power postoperatively than those in group A. There were no significant differences between the two studied groups as regard ambulation, range of motion and pain estimation. Conclusion: Since both blocks have comparable analgesic effect and opioid consumption rates, the increased quadriceps muscle strength and ability to ambulate on the first postoperative day is the driving factor in selecting the ACB. With the findings discussed in our study and in literature, an ACB is a viable option in place of a FNB in patients undergoing a total knee arthroplasty. Additional large participant randomized controlled studies should be conducted to further discover the benefits of an ACB in patients undergoing a total knee arthroplasty.


2006 ◽  
Vol 21 (5) ◽  
pp. 311-316 ◽  
Author(s):  
Victor M. Duarte ◽  
Wendy M. Fallis ◽  
Dean Slonowsky ◽  
Kwadwo Kwarteng ◽  
Colin K.L. Yeung

2018 ◽  
Vol 32 (10) ◽  
pp. 1020-1023 ◽  
Author(s):  
Masahiro Hasegawa ◽  
Shine Tone ◽  
Yohei Naito ◽  
Hiroki Wakabayashi ◽  
Akihiro Sudo

AbstractThe present study aimed to define the prevalence of pain persisting after total knee arthroplasty (TKA) and determine the impact of neuropathic pain. Knee pain after TKA was evaluated in 154 patients (222 knees with osteoarthritis) using a numerical rating scale (NRS) and followed up for a mean of 4.7 years. The patients were classified according to whether they had no or mild pain (NRS ≤ 3), or moderate-to-severe pain (NRS > 3), and then assigned to groups with nociceptive, unclear, or neuropathic pain based on responses to painDETECT questionnaires. Risk factors for these types of pain were determined. The ratio of patients with moderate-to-severe pain was 28% (62 knees). Thirteen patients (21 knees; 9%) experienced unclear pain. Patients with moderate-to-severe or unclear pain had malalignment and lower Knee Society knee scores. In conclusion, a significant number of patients experienced moderate-to-severe and unclear pain after TKA. Moderate-to-severe pain was associated with unclear pain.


2019 ◽  
pp. 001857871986764
Author(s):  
J. Lacie Bradford ◽  
Beatrice Turner ◽  
Megan A. Van Berkel

Purpose: Opioid use postoperatively has been linked to adverse events and an increase in opioid dependency. This retrospective study evaluated the effect of using liposomal bupivacaine (LB) for postoperative pain control on total opioid consumption, pain control, serious opioid-related adverse events (ORAEs), and hospital length of stay (LOS) in total knee arthroplasty (TKA), total hip arthroplasty (THA), laminectomy, hysterectomy, and abdominoplasty procedures when compared with a control group. Methods: Patients receiving LB from August 1, 2017, to February 1, 2018, for the aforementioned procedures were included for evaluation, and patients undergoing similar procedures who did not receive LB served as the control group. The principal outcome was opioid consumption through postoperative day 5 or discharge, whichever came first, assessed by morphine milligram equivalents (MMEs). Secondary outcomes included pain scores within 72 hours postoperation, hospital LOS, and serious ORAEs. Results: A total of 323 patients were identified for inclusion in the study: TKA, n = 144; THA, n = 48; laminectomy, n = 73; hysterectomy, n = 30; and abdominoplasty, n = 28. Liposomal bupivacaine use was associated with reduced postoperative opioid consumption compared with alternative therapies with a median 71 MME (25%-75%; interquartile range [IQR] = 32.5-148.5) versus 102 MME (25%-75%; IQR = 57-165), P < .005. However, higher numeric pain scores were reported in the LB group compared with the control group for postoperative day 0 with a median of 5.5 (25%-75%; IQR = 4.5-7.4) versus 5.5 (25%-75%; IQR = 4-7) in the control group ( P < .001) and on postoperative day 1 with a median of 6 (25%-75%; IQR = 4.5-7) versus 5.5 (25%-75%; IQR = 4.3-7), P < .001. There was no difference in hospital LOS or ORAEs. Conclusion: In this retrospective analysis of pain management after TKA, THA, laminectomy, hysterectomy, and abdominoplasty procedures, patients receiving LB consumed significantly less opioid medications. However, this was not associated with clinically meaningful improvements in pain scores, hospital LOS, or serious ORAEs.


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