New Antipsychotics in Treatment of Mood Instability and Cognitive Perceptual Symptoms in Borderline Personality Disorder

2012 ◽  
Vol 1 (1) ◽  
pp. 86-96 ◽  
Author(s):  
Silvio Bellino ◽  
Paola Bozzatello ◽  
Elena Brignolo ◽  
Filippo Bogetto
2015 ◽  
Vol 30 (8) ◽  
pp. 914-919 ◽  
Author(s):  
I. Baryshnikov ◽  
K. Aaltonen ◽  
M. Koivisto ◽  
P. Näätänen ◽  
B. Karpov ◽  
...  

AbstractBackgroundDifferential diagnosis between bipolar disorder (BD) and borderline personality disorder (BPD) is often challenging due to some overlap in symptoms and comorbidity of disorders. We investigated correlations in self-reported symptoms of BD and BPD in screening questionnaires at the levels of both total scores and individual items and explored overlapping dimensions.MethodsThe McLean Screening Instrument (MSI) for BPD and the Mood Disorder Questionnaire (MDQ) for BD were filled in by patients with unipolar and bipolar mood disorders (n = 313) from specialized psychiatric care within a pilot study of the Helsinki University Psychiatric Consortium. Pearson's correlation coefficients between total scores and individual items of the MSI and the MDQ were estimated. Relationships between MDQ and MSI were evaluated by exploratory factor analysis (EFA).ResultsThe correlation between total scores of the MDQ and MSI was moderate (r = 0.431, P < 0.001). Significant correlations were found between the MSI items of “impulsivity” and “mood instability” and all MDQ items (P < 0.01). In the EFA, the MSI “impulsivity” and “mood instability” items had significant cross-loadings (0.348 and 0.298, respectively) with the MDQ factor. The MDQ items of “irritability”, “flight of thoughts” and “distractibility” (0.280, 0.210 and 0.386, respectively) cross-loaded on the MSI factor.ConclusionsThe MDQ and MSI items of “affective instability”, “impulsivity”, “irritability”, “flight of thoughts” and “distractibility” appear to overlap in content. The other scale items are more disorder-specific, and thus, may help to distinguish BD and BPD.


2019 ◽  
Vol 41 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Lucas de Francisco Carvalho ◽  
Giselle Pianowski

Abstract Introduction Borderline personality disorder (BPD) is one of the most widely studied personality disorders (PDs). It recurrently shows traits of emotional lability, anxiety, separation insecurity, depressiveness, impulsiveness, risk exposure, and hostility, mainly affecting the domains of negative affectivity and antagonism. Objectives To investigate the most discriminant dimensions of the Dimensional Clinical Personality Inventory (Inventário Dimensional Clínico da Personalidade 2 [IDCP-2]) to distinguish people diagnosed with BPD from people without this diagnosis. Methods A total of 305 participants were included in this study: psychiatric outpatients diagnosed with BPD (n = 30), psychiatric outpatients diagnosed with other PDs (n = 75), and a community sample (n = 200). BPD traits were assessed using the dependency, mood instability, and inconsequence dimensions of the IDCP-2. Results Analysis of variance (ANOVA) comparisons indicated highest mean measures in the BPD group, and mood instability factors were the most discriminant ones when considering all groups. Applying the multiple regression analysis, we found an adjusted r 2 = 0.50, and hopelessness was the most predictive measure (β = 0.32; t = 6.19; p < 0.001). Conclusions We found discriminatory capacity for factors of all dimensions, although at different levels, and more consistent results to discriminate the BPD group from the community sample.


Crisis ◽  
2020 ◽  
pp. 1-7
Author(s):  
Jacqueline M. Frei ◽  
Vladimir Sazhin ◽  
Melissa Fick ◽  
Keong Yap

Abstract. Psychiatric hospitalization can cause significant distress for patients. Research has shown that to cope with the stress, patients sometimes resort to self-harm. Given the paucity of research on self-harm among psychiatric inpatients, a better understanding of transdiagnostic processes as predictors of self-harm during psychiatric hospitalization is needed. The current study examined whether coping styles predicted self-harm after controlling for commonly associated factors, such as age, gender, and borderline personality disorder. Participants were 72 patients (mean age = 39.32 years, SD = 12.29, 64% male) admitted for inpatient treatment at a public psychiatric hospital in Sydney, Australia. Participants completed self-report measures of coping styles and ward-specific coping behaviors, including self-harm, in relation to coping with the stress of acute hospitalization. Results showed that younger age, diagnosis of borderline personality disorder, and higher emotion-oriented coping were associated with self-harm. After controlling for age and borderline personality disorder, higher levels of emotion-oriented coping were found to be a significant predictor of self-harm. Findings were partially consistent with hypotheses; emotion-oriented but not avoidance-oriented coping significantly predicted self-harm. This finding may help to identify and provide psychiatric inpatients who are at risk of self-harm with appropriate therapeutic interventions.


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