scholarly journals Association of Hyperthyroidism and Thyroid Autoantibodies with Moyamoya Disease and Its Stroke Event: A Population-based Case-control Study and Meta-analysis

2018 ◽  
Vol 58 (3) ◽  
pp. 116-123 ◽  
Author(s):  
Jun Hyong AHN ◽  
Jin Pyeong JEON ◽  
Jeong Eun KIM ◽  
Eun Jin HA ◽  
Won-Sang CHO ◽  
...  
Keyword(s):  
Moyamoya Disease ◽  
Case Control Study ◽  
Meta Analysis ◽  
Population Based ◽  
Case Control ◽  
Thyroid Autoantibodies ◽  
Stroke Event ◽  
Control Study

Abstract W P174: Association of Moyamoya Disease With Thyroid Autoantibodies and Thyroid Function: A Case-control Study and Meta-analysis

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Chunyan Lei
Keyword(s):  
Prospective Study ◽  
Thyroid Function ◽  
Moyamoya Disease ◽  
Case Control Study ◽  
Matched Control ◽  
Meta Analysis ◽  
Thyroid Autoantibodies ◽  
Literature Searches ◽  
Hospital Study ◽  
Control Study

Background and Purpose: Evidence suggests that elevated thyroid function and elevated levels of thyroid autoantibodies are associated with risk of Moyamoya disease (MMD). Therefore we performed a meta-analysis of all available evidence, including unpublished data from our own center, in order to assess this association. Methods: We reviewed the English- and Chinese-language literature in major databases to identify studies examining the association between MMD and thyroid function or thyroid autoantibodies. We combined these data with those from our own prospective study conducted in our hospital. Results: In our center, 28 patients with MMD and 28 age-matched control patients with non-MMD stroke were included. Based on our literature searches, we identified two studies for inclusion in our meta-analysis, to which we added our own prospective study described above. Data from our hospital study indicated an association between risk of MMD and elevated thyroid autoantibodies (OR 9.00, 95% CI 1.03 to 78.94), but not between risk of MMD and elevated thyroid function (OR 5.87, 95% CI 0.64 to 53.93). Meta-analysis of our data with findings from the literature further supported the association with elevated thyroid autoantibodies (OR 8.77, 95% CI 4.45 to 17.29) and also indicated an association with elevated thyroid function (OR 9.74, 95% CI 2.18 to 43.49). Conclusions: Evidence strongly suggests that elevated thyroid autoantibodies and elevated thyroid function are independently associated with MMD. These clinical variables may require regular monitoring in patients with MMD.

scholarly journals Life course sun exposure and risk of prostate cancer: Population-based nested case-control study and meta-analysis

2009 ◽  
Vol 125 (6) ◽  
pp. 1414-1423 ◽  
Author(s):  
Rebecca Gilbert ◽  
Chris Metcalfe ◽  
Steven E. Oliver ◽  
David C. Whiteman ◽  
Chris Bain ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Life Course ◽  
Case Control Study ◽  
Meta Analysis ◽  
Sun Exposure ◽  
Population Based ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study
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