Early Diagnosis of Interstitial Pregnancy Associated to Assisted Reproductive Techniques Case Report

Heterotopic pregnancy is the condition where both intrauterine and ectopic pregnancy are present. It rarely occurs after natural conception, but is more common with assisted reproductive techniques, when more than one embryo is transferred. Quadruplet heterotopic pregnancy is exceedingly rare. Methods: A literature review was conducted aiming to highlight the diagnosis difficulties and the management options in heterotopic quadruplet pregnancies. Results: Nine relevant studies were identified by researching PubMed up to 2021 for “heterotopic quadruplet pregnancy”, “quadruplet intrauterine and ectopic pregnancy”, “synchronous intrauterine and ectopic pregnancy”. Conclusions: In this paper, we present a case of heterotopic quadruplet pregnancy and address the difficulty in diagnosing this condition and make formal recommendations.

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Inhibition of oocyte fertilization by assisted reproductive techniques and increased sperm DNA fragmentation in the presence of Candida albicans: a case report

Reproductive BioMedicine Online ◽

10.1016/s1472-6483(10)61104-2 ◽

2004 ◽

Vol 8 (5) ◽

pp. 569-573 ◽

Cited By ~ 15

Author(s):

Nunziatina Burrello ◽

Aldo E Calogero ◽

Anna Perdichizzi ◽

Mario Salmeri ◽

Rosario D'Agata ◽

...

Keyword(s):

Candida Albicans ◽

Case Report ◽

Dna Fragmentation ◽

Assisted Reproductive Techniques ◽

Sperm Dna Fragmentation ◽

Oocyte Fertilization ◽

Sperm Dna ◽

Reproductive Techniques

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Laparoscopic Strategy for Heterotopic Interstitial Pregnancy Following Assisted Reproductive Techniques

JSLS Journal of the Society of Laparoendoscopic Surgeons ◽

10.4293/jsls.2018.00109 ◽

2019 ◽

Vol 23 (2) ◽

pp. e2018.00109 ◽

Cited By ~ 1

Author(s):

Bingsi Gao ◽

Chunxia Cheng ◽

Qiong Pan ◽

Grace Johnson ◽

Xian Qin ◽

...

Keyword(s):

Assisted Reproductive Techniques ◽

Interstitial Pregnancy ◽

Reproductive Techniques

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Heterotopic Pregnancy in Natural Conception – A Case Report

International Journal of Women’s Health Care ◽

10.33140/ijwhc.06.03.06 ◽

2021 ◽

Vol 6 (3) ◽

Keyword(s):

Case Report ◽

Ultrasound Examination ◽

Tubal Pregnancy ◽

High Index ◽

Assisted Reproductive Techniques ◽

Heterotopic Pregnancy ◽

Timely Diagnosis ◽

Reproductive Techniques ◽

Natural Conception ◽

High Index Of Suspicion

Heterotopic gestation is very rare in natural conception but can be common with assisted reproductive techniques; a high index of suspicion can help in timely diagnosis and appropriate intervention. We report a case of heterotopic pregnancy in a 32-year-old woman presented with hemoperitoneum from ruptured right sided tubal pregnancy with live intrauterine gestation at 12 weeks of amenorrhea, diagnosed on clinical and ultrasound examination.

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Interstitial Pregnancy Managed with Single-dose Systemic Methotrexate: A Case Report

Journal of Nepal Medical Association ◽

10.31729/jnma.6595 ◽

2021 ◽

Vol 59 (241) ◽

pp. 932-934

Author(s):

Tulasa Basnet ◽

Punita Yadav ◽

Manoj Kumar Sah ◽

Jyotsna Yadav

Keyword(s):

Single Dose ◽

Case Report ◽

High Risk ◽

Mortality Rate ◽

Early Diagnosis ◽

Diagnostic Imaging ◽

Massive Hemorrhage ◽

Rare Type ◽

Interstitial Pregnancy ◽

Life Threatening

Interstitial pregnancy is a rare type of ectopic pregnancy with a high risk of massive hemorrhage on rupture as compared to ectopic on other sites. The mortality rate for the ruptured interstitial pregnancy is high. Therefore, early diagnosis of such pregnancy before the rupture occurs facilitates appropriate management and avoids life-threatening complications. With the advancement in diagnostic imaging modalities, early diagnosis and more conservative management for interstitial pregnancy have become possible. Here, we report a case of primigravida diagnosed with interstitial pregnancy with ultrasonography and successfully managed with a single dose of methotrexate.

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A case of heterotopic pregnancy after clomiphene-induced ovulation

SAGE Open Medical Case Reports ◽

10.1177/2050313x19873794 ◽

2019 ◽

Vol 7 ◽

pp. 2050313X1987379 ◽

Cited By ~ 1

Author(s):

Hanoof Ali Alqahtani

Keyword(s):

Case Report ◽

Fallopian Tube ◽

Rare Condition ◽

Assisted Reproductive Techniques ◽

Considerable Progress ◽

Heterotopic Pregnancy ◽

Intrauterine Pregnancy ◽

Induced Ovulation ◽

Reproductive Techniques ◽

History Of

Heterotopic pregnancy is a rare condition in which both intrauterine and extrauterine pregnancies occur simultaneously. It was reported to be very rare in normal conceived pregnancy. However, with the considerable progress of the assisted reproductive techniques, the incidence of heterotopic pregnancy increased. Furthermore, the incidence also increases in previous abortions. In this case report, we will present and discuss a patient who had heterotopic pregnancy after clomiphene-induced ovulation as well as a history of previous abortion where the extrauterine fallopian tube ruptured and was managed surgically while the intrauterine pregnancy was preserved.

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Misdiagnosis of interstitial pregnancy followed by circlage operation and failed induced midtrimester abortion: a case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20195371 ◽

2019 ◽

Vol 8 (12) ◽

pp. 5054

Author(s):

Nalini Sharma ◽

Anusmita Saha

Keyword(s):

Case Report ◽

Early Diagnosis ◽

Ectopic Pregnancy ◽

Medical Abortion ◽

Normal Response ◽

Rare Form ◽

Interstitial Pregnancy ◽

Mortality And Morbidity ◽

Expert Radiologist

Interstitial pregnancy is rare form of ectopic pregnancy that can expand up to 18 weeks leads to massive haemoperitoneum hence early diagnosis is imperative to decrease mortality and morbidity. Present case diagnosed as interstitial pregnancy at laparotomy when she had taken for hysterotomy after two failed courses of medical abortion. Clinicians should bear in mind the limitations of various investigations and should have a higher degree of suspicion for interstitial pregnancy Any deviation from normal response to administration of medical abortificient, such as failure to abort, should instigate the diagnosis of ectopic (interstitial) pregnancy by expert radiologist.

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