Primary aggressive chondroblastoma of the tibia

Chondroblastoma is a primary bone tumor in children, adolescents and young adults, which accounts for 1% of all bone tumors. Epiphyseal or epiphysometaphyseal localization, this lesion usually develops from secondary ossification centers close to the knee, shoulder and hip. Although chondroblastoma is a nonaggressive benign tumor, it can very rarely show a locally aggressive character or a malignant transformation or even metastases. We describe a histologically proven case of an aggressive, primary chondroblastoma of the tibia invading soft tissue in a 22-year-old girl.

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Soft tissue hemangioma with adjacent periosteal reaction simulating a primary bone tumor

Skeletal Radiology ◽

10.1007/s002560050057 ◽

1996 ◽

Vol 25 (2) ◽

pp. 174-177 ◽

Cited By ~ 21

Author(s):

John L. DeFilippo ◽

J. S. Yu ◽

Lawrence Weis ◽

Joel Lucas

Keyword(s):

Soft Tissue ◽

Bone Tumor ◽

Periosteal Reaction ◽

Primary Bone Tumor ◽

Primary Bone

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Demographic, clinico-pathological features and management pattern of primary bone tumors in a tertiary care hospital of South India

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20214962 ◽

2021 ◽

Vol 8 (1) ◽

pp. 60

Author(s):

Subbiah Shanmugam ◽

Sujay Susikar ◽

Bharanidharan T. ◽

Arun Victor Jebasingh

Keyword(s):

Bone Tumor ◽

Bone Tumors ◽

Tertiary Care ◽

Tumor Location ◽

Care Hospital ◽

Pathological Features ◽

Primary Bone Tumor ◽

Primary Bone Tumors ◽

True Incidence ◽

Primary Bone

Background: Primary bone tumors are very rare tumors. The true incidence of bone tumors is not well established and is under reported due to rarity and lack of accurate registries. Hence it is essential to study about the demographic, clinico-pathological features and the pattern of surgical management of bone tumors. The aim of this study is to analyze the demographic and clinico-pathological features of primary bone tumors that were managed by surgery.Methods: A retrospective analysis of all patients with primary bone tumor who were treated by surgery from 2012 to 2019 was done. The age, sex distribution, histopathology, location of the tumor and surgical procedure done were analyzed.Results: Among 103 patients analyzed, 66 (64%) were men and 37 (36%) were women. Primary bone tumors most commonly presented in 11 to 20 years of age with 35 (33.9%) patients occurring in this age group. Osteosarcoma was the most common primary bone tumor and it occurred in 49 (47.6%) patients, out of which 34 (69.3%) patients were below 20 years of age. Giant cell tumor was the most common benign bone tumor and it occurred in 22 patients, out of which nine (40.9%) patients were of age 21 to 30 years. Distal femur was the most common site with 39 (37.9%) patients. The limb preservation rate for malignant appendicular bone tumors was 69.0%.Conclusions: The diagnosis of bone tumor depends not only on histopathological features but also needs correlation with age, clinical features, tumor location and radiological features for confirmation of diagnosis.

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Lymphography in Bone and Soft Tissue Sarcomas. Experiences from Three Institutions

Tumori Journal ◽

10.1177/030089168006600606 ◽

1980 ◽

Vol 66 (6) ◽

pp. 721-728 ◽

Cited By ~ 2

Author(s):

Kaj Tallroth ◽

Francisco Makai ◽

Renato Musumeci

Keyword(s):

Lymph Node ◽

Soft Tissue ◽

Diagnostic Accuracy ◽

Bone Tumors ◽

Soft Tissue Sarcomas ◽

Hematogenous Spread ◽

Primary Bone Tumor ◽

Bone Sarcomas ◽

Neurogenic Sarcoma ◽

Primary Bone

The case material was collected from 3 Institutions with a total of 411 patients: 217 with primary bone tumor and 224 with soft tissue sarcomas. In the majority of patients lymphography was performed during the initial diagnostic workup. The lymphograms were interpreted as negative or positive for metastases. In bone tumors, the incidence of metastases was 21 %, ranging from 28 % for osteosarcoma to 18 % for Ewing's sarcoma and 13 % for chondrosarcoma. In tumors of the soft tissue, the frequency was somewhat higher (28%), with special regard to rhabdomyosarcoma (53%), anaplastic sarcoma (67 %), neurogenic sarcoma (42%) and synovial sarcoma (35%). In the group of bone sarcomas, primary hematogenous spread was 3 times more frequent than lymphogenous spread, while in soft tissue sarcomas, with a higher incidence of lymphatic spread, this finding was inverted. In the more consistent tumor groups, the occurrence of lymphatic metastases indicated a significant worsening of the prognosis. In 96 patients, lymph node biopsies were performed and the radiologic histologic correlation gave evidence of a 91.7 % overall diagnostic accuracy.

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Deep soft-tissue leiomyoma of the forearm mimicking a primary bone tumor of the ulna

Radiology Case Reports ◽

10.2484/rcr.v9i3.960 ◽

2014 ◽

Vol 9 (3) ◽

pp. 960 ◽

Cited By ~ 3

Author(s):

Rajoo Ramachandran ◽

Rajeswaran Rangaswami ◽

Dorai Kumar Raja ◽

Gouthaman Shanmugasundaram

Keyword(s):

Soft Tissue ◽

Bone Tumor ◽

Deep Soft Tissue ◽

Primary Bone Tumor ◽

Primary Bone

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Malignant Osteoid Matrix Bone Tumors

Musculoskeletal Imaging Volume 1 ◽

10.1093/med/9780190938161.003.0053 ◽

2019 ◽

pp. 251-258

Author(s):

Abhijit Datir

Keyword(s):

Bone Tumor ◽

Bone Tumors ◽

Age Groups ◽

Bone Destruction ◽

Tissue Mass ◽

Primary Bone Tumor ◽

Radiologic Findings ◽

Conventional Osteosarcoma ◽

Skip Lesions ◽

Primary Bone

Chapter 53 discusses malignant osteoid matrix bone tumors and focuses on several types of osteosarcoma, ranging from the most common, conventional osteosarcoma, to secondary osteosarcomas, such as Paget and postradiation sarcomas. Osteosarcoma is the most common primary bone tumor in children and adolescents, and second most frequent primary malignant bone tumor if all age groups are considered. A short discussion on typical radiologic findings with classic examples of various types of osteosarcoma is included. Conventional radiographs show an aggressive lesion with permeative bone destruction, extraosseous soft tissue mass and cortical disruption with periosteal reaction. MRI is useful for assessing tumor extent and skip lesions. Treatment includes surgery and chemotherapy.

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Profile of Musculoskeletal Tumor in Saiful Anwar General Hospital Malang from January 2011 until December 2018

Berkala Kedokteran ◽

10.20527/jbk.v16i2.9218 ◽

2020 ◽

Vol 16 (2) ◽

pp. 81

Author(s):

Istan Irmansyah Irsan ◽

Satria Pandu Persada Isma ◽

Abdul Aziz ◽

Muhammad Hilman Bimadi ◽

I Gusti Ngurah Arga Aldrian Oktafandi

Keyword(s):

Soft Tissue ◽

General Hospital ◽

Bone Tumor ◽

Bone Tumors ◽

Malignant Tumors ◽

Soft Tissue Tumors ◽

Musculoskeletal Tumor ◽

Primary Bone Tumors ◽

Musculoskeletal Tumors ◽

Primary Bone

Abstract: Musculoskeletal tumors are relatively rare, with 0.2%-0.5% of all malignant tumors in all ages. The geographic distribution of musculoskeletal tumors varies significantly around the world. This study aims to describe the musculoskeletal tumor profile in Saiful Anwar General Hospital. All data were obtained from the department of orthopaedic and traumatology database, Saiful Anwar general hospital. Thus, patients who were diagnosed with either bone tumor or soft tissue tumor between January 2011 to December 2018 were selected for the present study. The clinical-pathological conference (CPC) was carried out to ensure the validity of all the registered data. A total of 577 patients with tumors from January 2011 to December 2018 was obtained. Out of all the cases, 439 (76%) cases are bone tumors, and the remaining 138 (24%) cases are soft tissue tumors. The most frequent locations of the musculoskeletal tumors are the long bones of the thigh and lower leg. This study shows an increasing trend in musculoskeletal tumors incidence, despite decreasing numbers in several years. This result goes along with a rising trend in malignancy cases with a higher amount compared to the benign one. Moreover, MBD and osteosarcoma were found to be the most common tumor and primary bone tumors, respectively. However, the fact that there is some data loss in the study limited the study for a more accurate result. Keywords: Musculoskeletal tumor; Bone tumor; Osteosarcoma; Malang; East Java

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Scintigraphy with 99m Tc-Phosphonate and 67Gallium in Patients Suspected of Primary Bone Tumors

Nuklearmedizin ◽

10.1055/s-0037-1620567 ◽

1982 ◽

Vol 21 (04) ◽

pp. 136-139 ◽

Cited By ~ 2

Author(s):

C.-J. Edeling

Keyword(s):

Soft Tissue ◽

Bone Scintigraphy ◽

Primary Tumor ◽

Bone Tumors ◽

Whole Body ◽

Skeletal Metastases ◽

Malignant Bone Tumors ◽

67Ga Scintigraphy ◽

Primary Bone Tumors ◽

Primary Bone

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.

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A retrospective analysis of computed tomography guided biopsy in the diagnosis of primary bone tumors

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20171903 ◽

2017 ◽

Vol 3 (3) ◽

pp. 569

Author(s):

Kuriakku Puthur Dominic ◽

Davis Dijoe ◽

Jacob Toms

Keyword(s):

Computed Tomography ◽

Bone Tumors ◽

Diagnostic Efficiency ◽

Ct Guided ◽

Primary Bone Tumor ◽

Primary Bone Tumors ◽

Guided Biopsy ◽

Ct Guided Biopsy ◽

Significant Step ◽

Primary Bone

Background: Primary bone tumors account for a small yet significant number in the total incidence of tumors. Computed tomography (CT) guided percutaneous core biopsy is a novel yet significant step in the approach towards the diagnosis of bone tumors and is increasingly performed by orthopaedic oncologists around the world. This study is aimed to evaluate the diagnostic accuracy of CT guided biopsy in the diagnosis of primary bone tumors. Methods: Patients who underwent CT guided biopsy and subsequent excision for primary bone tumors from January 2008 to July 2015 were analysed. CT guided biopsy results were compared with post-operative histopathological reports to evaluate its sensitivity and specificity.Results: A total of 161 patients were included in the retrospective study. Among them, 147 were true positives, 7 were false negatives, 6 were true negatives and one was false positive. The sensitivity of CT guided biopsy in the diagnosis of primary bone tumor was 95.4 % with specificity of 85.7% with a diagnostic efficiency of 90.5%. The complication rate was 4.3%.Conclusions: CT guided biopsy is a safe, simple and effective procedure to rule out and rule in the diagnosis of primary bone tumors.

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