scholarly journals A retrospective analysis of computed tomography guided biopsy in the diagnosis of primary bone tumors

2017 ◽  
Vol 3 (3) ◽  
pp. 569
Author(s):  
Kuriakku Puthur Dominic ◽  
Davis Dijoe ◽  
Jacob Toms
Keyword(s):  
Computed Tomography ◽  
Bone Tumors ◽  
Diagnostic Efficiency ◽  
Ct Guided ◽  
Primary Bone Tumor ◽  
Primary Bone Tumors ◽  
Guided Biopsy ◽  
Ct Guided Biopsy ◽  
Significant Step ◽  
Primary Bone

<p><strong>Background:</strong> Primary bone tumors account for a small yet significant number in the total incidence of tumors. Computed tomography (CT) guided percutaneous core biopsy is a novel yet significant step in the approach towards the diagnosis of bone tumors and is increasingly performed by orthopaedic oncologists around the world. This study is aimed to evaluate the diagnostic accuracy of CT guided biopsy in the diagnosis of primary bone tumors. <strong></strong></p><p><strong>Methods:</strong> Patients who underwent CT guided biopsy and subsequent excision for primary bone tumors from January 2008 to July 2015 were analysed. CT guided biopsy results were compared with post-operative histopathological reports to evaluate its sensitivity and specificity.</p><p><strong>Results:</strong> A total of 161 patients were included in the retrospective study. Among them, 147 were true positives, 7 were false negatives, 6 were true negatives and one was false positive. The sensitivity of CT guided biopsy in the diagnosis of primary bone tumor was 95.4 % with specificity of 85.7% with a diagnostic efficiency of 90.5%. The complication rate was 4.3%.</p><p><strong>Conclusions:</strong> CT guided biopsy is a safe, simple and effective procedure to rule out and rule in the diagnosis of primary bone tumors.</p>

scholarly journals Imaging of Mixed and Radiopaque Jaw Lesions

2020 ◽  
Vol 24 (05) ◽  
pp. 558-569
Author(s):  
Filip M. Vanhoenacker ◽  
Frederik Bosmans ◽  
Charlotte Vanhoenacker ◽  
Anja Bernaerts
Keyword(s):  
Computed Tomography ◽  
Bone Tumors ◽  
Developmental Disorders ◽  
Clinical Presentation ◽  
Bone Diseases ◽  
Cone Beam ◽  
Panoramic Radiographs ◽  
Primary Bone Tumors ◽  
Imaging Characteristics ◽  
Primary Bone

AbstractRadiopaque lesions and lesions of mixed density are less frequent than radiolucent lesions of the jawbones. They comprise a spectrum of odontogenic and non-odontogenic lesions. The latter group includes inherited and developmental disorders, osteomyelitis, and benign and malignant primary bone tumors and metastases. Most odontogenic radiopaque or mixed lesions are either related to the apex or more rarely to the crown of the tooth, although there are exceptions to this rule. Some lesions, such as a torus mandibularis and torus palatinus, have a characteristic location, whereas others show no relationship to the dentition. This article describes the most characteristic and prevalent radiopaque and mixed lesions of the jaws and their imaging characteristics. Paget's disease, fibrous dysplasia, and rare sclerotic bone diseases of the maxillofacial bones are discussed elsewhere in this issue. Careful correlation of clinical presentation, panoramic radiographs, cone beam computed tomography, and histopathology are the cornerstones for appropriate lesion characterization.

scholarly journals Demographic, clinico-pathological features and management pattern of primary bone tumors in a tertiary care hospital of South India

2021 ◽  
Vol 8 (1) ◽  
pp. 60
Author(s):  
Subbiah Shanmugam ◽  
Sujay Susikar ◽  
Bharanidharan T. ◽  
Arun Victor Jebasingh
Keyword(s):  
Bone Tumor ◽  
Bone Tumors ◽  
Tertiary Care ◽  
Tumor Location ◽  
Care Hospital ◽  
Pathological Features ◽  
Primary Bone Tumor ◽  
Primary Bone Tumors ◽  
True Incidence ◽  
Primary Bone

<p><strong>Background</strong>: Primary bone tumors are very rare tumors. The true incidence of bone tumors is not well established and is under reported due to rarity and lack of accurate registries. Hence it is essential to study about the demographic, clinico-pathological features and the pattern of surgical management of bone tumors. The aim of this study is to analyze the demographic and clinico-pathological features of primary bone tumors that were managed by surgery.</p><p><strong>Methods</strong>: A retrospective analysis of all patients with primary bone tumor who were treated by surgery from 2012 to 2019 was done. The age, sex distribution, histopathology, location of the tumor and surgical procedure done were analyzed.</p><p><strong>Results</strong>: Among 103 patients analyzed, 66 (64%) were men and 37 (36%) were women. Primary bone tumors most commonly presented in 11 to 20 years of age with 35 (33.9%) patients occurring in this age group. Osteosarcoma was the most common primary bone tumor and it occurred in 49 (47.6%) patients, out of which 34 (69.3%) patients were below 20 years of age. Giant cell tumor was the most common benign bone tumor and it occurred in 22 patients, out of which nine (40.9%) patients were of age 21 to 30 years. Distal femur was the most common site with 39 (37.9%) patients. The limb preservation rate for malignant appendicular bone tumors was 69.0%.</p><p><strong>Conclusions</strong>: The diagnosis of bone tumor depends not only on histopathological features but also needs correlation with age, clinical features, tumor location and radiological features for confirmation of diagnosis.</p>

scholarly journals Benign Notochordal Cell Tumor of the Sacrum with Atypical Imaging Features: The Value of CT Guided Biopsy for Diagnosis

2013 ◽  
Vol 7 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Dario Pasalic ◽  
Patrick H. Luetmer ◽  
Christopher H. Hunt ◽  
Peter S. Rose ◽  
Felix E. Diehn ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Definitive Diagnosis ◽  
Cell Tumor ◽  
Invasive Technique ◽  
Imaging Features ◽  
Ct Guided ◽  
Notochordal Cell ◽  
Orthopedic Surgeons ◽  
Guided Biopsy ◽  
Ct Guided Biopsy

We report a case of a benign notochordal cell tumor (BNCT) of the sacrum with atypical imaging features, which was incidentally discovered in a 74-year-old man undergoing evaluation for progressively worsening hip and back pain. It is important for radiologists, pathologists and orthopedic surgeons to be aware of the diagnosis of BNCT and be familiar with its radiographic features to avoid unnecessary treatment. This case illustrates the advantage of percutaneous computed tomography (CT)-guided biopsy as a minimally invasive technique for definitive diagnosis of a BNCT with atypical imaging features.

scholarly journals Primary Bone Tumor of the Spine—An Evolving Field: What a General Spine Surgeon Should Know

2019 ◽  
Vol 9 (1_suppl) ◽  
pp. 108S-116S ◽  
Author(s):  
Raphaële Charest-Morin ◽  
Charles G. Fisher ◽  
Arjun Sahgal ◽  
Stefano Boriani ◽  
Ziya L. Gokaslan ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Bone Tumors ◽  
Treatment Algorithm ◽  
Significant Risk ◽  
Primary Bone Tumor ◽  
Primary Bone Tumors ◽  
Quaternary Centers ◽  
Treatment Paradigm ◽  
Primary Bone ◽  
Spine Surgeon

Study Design: A narrative review of the literature. Objective: This article reviews the general principles of treatment and investigation for primary bone tumors of the spine. Furthermore, it explores the emerging alternatives. Methods: A review was performed using Medline, Embase, and Cochrane databases. Results: Primary bone tumors of the spine are rare entities that general spine surgeons may encounter only a few times in their career. The treatment algorithm of these complex tumors is filled with nuances and is evolving constantly. For these reasons, patients should be referred to experienced tertiary or quaternary centers who can offer a comprehensive multidisciplinary approach. For most malignant spinal bone tumors, surgery remains the cornerstone of treatment. Respecting oncologic principles has been associated with improved survival and decreased local recurrence in multiple settings. However, even in experienced centers, these surgeries carry a significant risk of adverse events and possible long-term neurologic impairment. The associated morbidity of these procedures and the challenges of local recurrence have encouraged professionals caring for these patients to explore alternatives or adjuncts to surgical treatment. Conclusions: Over the past few years, several advances have occurred in medical oncology, radiation oncology and interventional radiology, changing the treatment paradigm for some tumors. Other advances still need to be refined before being applied in a clinical setting.

scholarly journals Combined CT guided tru-cut biopsy and imprint cytology in the diagnosis of bone tumors and tumor like lesions

2016 ◽  
Vol 7 (6) ◽  
pp. 40-42
Author(s):  
Moothiringode Chitrabhanu Savithri ◽  
Kanjirakkad Kavitha ◽  
Dominic Puthoor
Keyword(s):  
Bone Tumors ◽  
Bone Lesions ◽  
Imprint Cytology ◽  
Medical Sciences ◽  
Ct Guided ◽  
Primary Bone Tumors ◽  
Definitive Therapy ◽  
Plasma Cell Neoplasms ◽  
Primary Bone ◽  
Tumor Like Lesions

Background: Bone lesions are often histologically  heterogenous. The advantage of tru-cut biopsies in this context is that they provide a safe and accurate biopsy technique that can be performed in less specialized centers.  In this series we found combination of biopsy and cytology helpful in diagnosing bone lesions. However clinical picture and radiologic features are vital in arriving at a final diagnosis.Aims and Objective: 1) To assess the diagnostic accuracy of combined CT guided tru-cut biopsy and imprint cytology  in the diagnosis of bone tumors and tumor like lesions. 2)To analyze the spectrum of different bone lesions.Materials and Methods: 108 consecutive cases of bone lesions for which CT guided  tru-cut biopsy and imprint cytology were done between June 2010 and april 2012 were retrospectively studied. Both smears and biopsies were categorized into five groups.Correlation between biopsy and cytology were also evaluated.Results: Total number of cases were 108 of which 8 cases were inconclusive . In 100 cases a useful opinion could be given. There were 36 cases of primary bone tumors, 13 cases of plasma cell neoplasms, 42 metastatic tumors, 9 non neoplastic lesions and 8 inconclusive cases. Conclusion: Preliminary diagnosis of bone lesions before definitive therapy helps to avoid unnecessary surgical procedures. Tru cut biopsies supplemented by imprint cytology can provide definitive diagnosis in majority of cases.Asian Journal of Medical Sciences Vol.7(6) 2016 40-42

scholarly journals Results of Percutaneous Computed Tomography-Guided Biopsy of Adrenal Lesions and Spectrum of Computed Tomography Findings

2020 ◽  
Vol 10 ◽  
pp. 16
Author(s):  
Sriharsha Gunna ◽  
Zafar Neyaz ◽  
Eesh Bhatia ◽  
Rungmei S Marak ◽  
Richa Mishra ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Multidetector Ct ◽  
Diagnostic Yield ◽  
Major Complication ◽  
Malignant Neoplasms ◽  
Safe Procedure ◽  
Ct Scanner ◽  
Ct Guided ◽  
Guided Biopsy ◽  
Ct Guided Biopsy

Objective: Adrenal enlargement occurs in various conditions such as infections, benign, and malignant neoplasms. Percutaneous computed tomography (CT)-guided adrenal biopsy is a safe method for obtaining tissue specimen in cases where diagnosis cannot be established on imaging and biochemical grounds. The study aims to evaluate diagnostic yield, accuracy, and complications of percutaneous CT-guided adrenal biopsies. Furthermore, CT findings of various adrenal lesions have been described. Materials and Methods: Data of CT-guided adrenal biopsies performed from September 2009 to May 2019 were analyzed. Biopsies were performed on a 64-slice or a 128-slice multidetector CT scanner using a coaxial technique. Pathological and microbiological reports were retrieved from the hospital information system. Clinical details were obtained from clinical case records. Results: CT-guided adrenal biopsies were performed in 48 patients, 37 males and 11 females. Adrenal insufficiency was present in 31 (64%) cases and bilateral adrenal glands were affected in 35 (73%). Biopsy yielded a diagnosis in 35 cases (72.9%). The final diagnosis was achieved in 43 (90%) cases. Combined accuracy of CT-guided biopsy for identifying malignancy and infection was 88.3%. Adrenal histoplasmosis (AH) was the most common entity diagnosed (44%). After combining histopathology and microbiology results, the sensitivity for diagnosing AH was 100%. One (2%) patient had a major complication in the form of intra-abdominal hemorrhage requiring transfusion. Local hematoma and mild stable pneumothorax were noted in one patient each. Conclusion: Percutaneous CT-guided biopsy is a safe procedure for the diagnosis of adrenal lesions. It has good accuracy for diagnosing adrenal conditions such as infections and malignancies. However, the specific diagnosis of benign adrenal lesions was difficult to make. AH, tuberculosis, and metastasis have overlapping imaging findings.

Primary Adrenal Tuberculosis: Role of Computed Tomography and CT-Guided Biopsy in Diagnosis

2006 ◽  
Vol 76 (3) ◽  
pp. 285-287 ◽  
Author(s):  
E.N. Liatsikos ◽  
C.P. Kalogeropoulou ◽  
Z. Papathanassiou ◽  
I. Tsota ◽  
A. Athanasopoulos ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ct Guided ◽  
Guided Biopsy ◽  
Ct Guided Biopsy

Computed Tomography-Guided Biopsy Assisted by 18F-FDG Coincidence Imaging for Solid Tumours

2019 ◽  
Vol 9 (2) ◽  
pp. 366-370
Author(s):  
Feng Chen ◽  
Yunlei Pan ◽  
Tianzeng Lin ◽  
Shan Chen ◽  
Yuan Hong
Keyword(s):  
Computed Tomography ◽  
Solid Tumour ◽  
Final Diagnosis ◽  
Solid Tumours ◽  
Ct Guided ◽  
Guided Biopsy ◽  
Needle Position ◽  
Significant Difference ◽  
Ct Guided Biopsy ◽  
Coincidence Imaging

Objective: Early diagnosis of solid tumour is the key to making treatment plans. The traditional computed tomography (CT)-guided percutaneous biopsy often makes it difficult to determine the puncture point. The aim of this study is to analyze the collaborative application value of CT-guided biopsy assisted by 18F-FDG coincidence imaging for solid tumours. Methods: A retrospective analysis of 15 patients who underwent routine radiological examination can not form a correct diagnosis on body solid tumour. The needle was introduced under CT guidance in a step-by-step technique and correct needle position in the centre of FDG high concentration area in coincidence imaging. The biopsy specimens were examined under light microscopy and immunofluorescence. Result: All the lesions were successfully punctured, and the final diagnosis was malignant in 14 cases and benign in 1 cases. The sensitivity of CT-guided biopsy assisted by coincidence imaging was 92.9% (13/14), and the specificity was 100% (1/1). Compared with clinical final diagnosis, there was no significant difference between the two groups (P >0.05). Two cases of lung biopsy patients had a small amount of blood in sputum after operation. Conclusion: The CT-guided biopsy assisted by 18F-FDG coincidence imaging may improve the diagnostic capability, especially in cases when a definitive diagnosis by imaging alone is difficult to make.

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