A Current Perspective of Imagery in Psychoanalysis

1986 ◽  
Vol 5 (3) ◽  
pp. 199-209 ◽  
Author(s):  
Erma Dosamantes-Alperson
Keyword(s):  
Object Relations ◽  
Forward Movement ◽  
Psychoanalytic Treatment ◽  
Current Perspective ◽  
Transference And Countertransference ◽  
Different Types ◽  
A Current

Two schools of thought concerning the value of imagery in psychoanalysis are contrasted. Discussion centers on the kinds of object relations manifested in the images of different types of patients, the role of imagery in internalizing particular analyst functions, and the value of attending to transference and countertransference images in promoting the forward movement of psychoanalytic treatment.

scholarly journals Heparin-induced thrombocytopenia: research and clinical updates

Hematology ◽  
2016 ◽  
Vol 2016 (1) ◽  
pp. 262-268 ◽  
Author(s):  
Oluwatoyosi Onwuemene ◽  
Gowthami M. Arepally
Keyword(s):  
Limited Data ◽  
Platelet Factor ◽  
Heparin Induced Thrombocytopenia ◽  
Diagnostic Strategies ◽  
Immune Mediated ◽  
Emerging Therapies ◽  
Current Perspective ◽  
Clinical Advances ◽  
A Current

Abstract Heparin-induced thrombocytopenia (HIT) remains an important diagnosis to consider in hospitalized patients developing thrombocytopenia. HIT is an immune-mediated prothrombotic disorder caused by antibodies to platelet factor 4 (PF4) and heparin. Recent basic scientific studies have advanced our understanding of disease pathogenesis through studies of the PF4/heparin structure, immune mechanisms, and cellular basis of thrombosis. Clinical advances have also occurred in areas of HIT prevention, description of disease variants, and diagnostic strategies. Emerging anticoagulants with the potential to change HIT treatment are evolving, although with limited data. This review will provide a current perspective on HIT pathogenesis, disease features, diagnostic strategies, and role of emerging therapies for the management of HIT.

The Journey of Thiazolidinediones as Modulators of PPARs for the Management of Diabetes: A Current Perspective

2019 ◽  
Vol 25 (23) ◽  
pp. 2540-2554 ◽  
Author(s):  
Waquar Ahsan
Keyword(s):  
Peroxisome Proliferator ◽  
Expression Of Genes ◽  
Current Perspective ◽  
Drug Designing ◽  
Peroxisome Proliferator Activated Receptors ◽  
To Come ◽  
Ppar Ligands ◽  
A Current

Peroxisome Proliferator-Activated Receptors (PPARs) also known as glitazone receptors are a family of receptors that regulate the expression of genes and have an essential role in carbohydrate, lipid and protein metabolism apart from other functions. PPARs come in 3 sub-types: PPAR-α, PPAR-β/δ and PPAR-γ - with PPAR-γ having 2 isoforms - γ1 and γ2. Upon activation, the PPARs regulate the transcription of various genes involved in lipid and glucose metabolism, adipocyte differentiation, increasing insulin sensitivity, prevention of oxidative stress and to a certain extent, modulation of immune responses via macrophages that have been implicated in the pathogenesis of insulin resistance. Hence, PPARs are an attractive molecular target for designing new anti-diabetic drugs. This has led to a boost in the research efforts directed towards designing of PPAR ligands - particularly ones that can selectively and specifically activate one or more of the PPAR subtypes. Though, PPAR- γ full agonists such as Thiazolidinediones (TZDs) are well established agents for dyslipidemia and type 2 diabetes mellitus (T2D), the side effect profile associated with TZDs has potentiated an imminent need to come up with newer agents that act through this pathway. Several newer derivatives having TZD scaffold have been designed using structure based drug designing technique and computational tools and tested for their PPAR binding affinity and efficacy in combating T2D and some have shown promising activities. This review would focus on the role of PPARs in the management of T2D; recently reported TZD derivatives which acted as agonists of PPAR- γ and its subtypes and are potentially useful in the new drug discovery for the disease.

Genetics of Stuttering

1996 ◽  
Vol 39 (4) ◽  
pp. 771-784 ◽  
Author(s):  
Ehud Yairi ◽  
Nicoline Ambrose ◽  
Nancy Cox
Keyword(s):  
Familial Aggregation ◽  
Twin Studies ◽  
Clinical Work ◽  
Genetic Component ◽  
Future Research ◽  
Epidemiologic Factors ◽  
Current Perspective ◽  
Genetic And Environmental Factors ◽  
A Current

The fact that stuttering runs in families has been documented over a long period and has led to speculations and research about the role of a genetic component to this disorder. Although the genetic factor cannot be proved by familial aggregation and twin studies alone, such research has continued to provide support for a relationship between stuttering and genetics. The purposes of this article are to review and critique the research in this area. The article first assesses research methodologies that have been employed in familial studies of stuttering. It proceeds to review and critique incidence, twin, and aggregation studies. In addition, it includes sections on subgroups, genetic models of stuttering, and implications for future research as well as for clinical work. With a focus on improved methodology and recent findings, a current perspective on our knowledge of the genetic component to stuttering is provided. Among other conclusions, the article emphasizes that failure to consider epidemiologic factors has probably biased previous results regarding the genetics of stuttering. New preliminary data also appear to provide evidence that spontaneous recovery and chronicity are influenced by genetic factors. Generally, however, the review of incidence and twin studies, as well as of evidence for the various inheritance models, confirms previous conclusions about the interaction between genetic and environmental factors in stuttering.

A Current Perspective on Cerebellar Research

2000 ◽  
Vol 6 (4) ◽  
pp. 510-511
Author(s):  
Haruo Kashima
Keyword(s):  
Synaptic Plasticity ◽  
Motor Learning ◽  
Cambridge University ◽  
Good Samaritan ◽  
Current Perspective ◽  
Brain Sciences ◽  
A Current

This is a reprint of one issue in the Cambridge University Press journal Behavioral and Brain Sciences, originally based on the symposium Controversies in neuroscience IV: Motor learning and synaptic plasticity in the cerebellum, held in Portland Oregon on August 24 to 26, 1993. These symposia were organized by the Robert S. Dow Neurological Sciences Institute and supported by NIH, NSF, and the Good Samaritan Foundation. The subjects of the symposium were the role of the cerebellum in motor learning and the connection between motor learning and synaptic plasticity.

scholarly journals Role of Dendritic Cells in Pathogen Infections: A Current Perspective

2021 ◽  
Author(s):  
José Luis Muñoz-Carrillo ◽  
Juan Francisco Contreras-Cordero ◽  
Oscar Gutiérrez-Coronado ◽  
Paola Trinidad Villalobos-Gutiérrez ◽  
Luis Guillermo Ramos-Gracia ◽  
...  
Keyword(s):  
Immune Response ◽  
Dendritic Cells ◽  
Adaptive Immunity ◽  
Host Defense ◽  
Phagocytic Activity ◽  
Innate And Adaptive Immunity ◽  
Current Perspective ◽  
Bacteria And Fungi ◽  
A Current

Dendritic cells (DC) represent an important link between innate and adaptive immunity, which play an important role during the immune response against pathogens. There are several populations and subpopulations of DC, but mainly two subpopulations are characterized: the classic DC specialized in the processing and presentation of the antigen; and the plasmacytoid DC that have a high phagocytic activity and capacity for the production of cytokines. This chapter aims to present the current aspects related to the most relevant characteristics and functions of DC, as well as their role in host defense against infections by viruses, parasites, bacteria, and fungi.

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