scholarly journals Pros and Cons of Nebulizer Treatment in Asthma Exacerbation During the COVID-19 Pandemic

2021 ◽  
Vol 19 (1) ◽  
pp. 1-5
Author(s):  
Ayşe Bilge ÖZTÜRK ◽  
Ayşe Baccıoğlu ◽  
Özge Uysal Soyer ◽  
Ersoy Civelek ◽  
Bülent Enis Şekerel ◽  
...  
Keyword(s):  
Infection Control ◽  
Severe Asthma ◽  
Asthma Exacerbation ◽  
Aerosol Therapy ◽  
Home Setting ◽  
Asthma Exacerbations ◽  
Asthma Attack ◽  
Viral Particles ◽  
Pros And Cons ◽  
Keywords Asthma

ABSTRACT Nebulizers generate aerosols and may potentially transmit respiratory viral particles including SARS-CoV-2. There is a great concern about the use of a nebulizer in the treatment of asthma exacerbations in the hospital or home setting during the COVID-19 pandemic and its use is not recommended unless essential. However, aerosol therapy should not be avoided in obligatory indications. Therefore, indications of nebulizer use during the pandemic should be evaluated on an individual basis in case of a severe asthma attack, and infection control recommendations should be followed by clinicians while using nebulizers. In this article, we aimed to assess the safety in addition to the “pro” and “con” sides of nebulizer treatment in asthma exacerbation during the COVID-19 pandemic. Keywords: Asthma, coronavirus disease 2019, COVID-19, SARS-CoV-2, nebulizers

scholarly journals Risk factors associated with severe asthma exacerbations in children attending Alexandria University Children’s Hospital, Egypt

2018 ◽  
Vol 5 (12) ◽  
pp. 5019
Author(s):  
Ihab H. El Sawy ◽  
Reham M. Wagdy ◽  
Afaf G. Ibrahim ◽  
Suzy W. Ibrahim
Keyword(s):  
Risk Factors ◽  
Severe Asthma ◽  
Asthma Exacerbation ◽  
Mild Asthma ◽  
Factors Associated ◽  
Children's Hospital ◽  
Asthma Exacerbations ◽  
Severe Asthma Exacerbation ◽  
Children’S Hospital ◽  
History Of

Background: Severe asthma exacerbation is one of the common pediatric medical emergencies that necessitates hospital visits. The study aimed to identify risk factors associated with pediatric severe asthma exacerbations that might have the potential to guide the parents for early medical consultations and physicians at primary health care centers for proper management.Methods: A case-control study was conducted on over 100 asthmatic children below 12 years attending the Emergency Department of Alexandria University Children’s Hospital in acute exacerbation. Based on a modified pulmonary index score, the patients were allocated into 2 groups; study group (50 patients with severe asthma exacerbation) and control group (50 patients with mild asthma exacerbations). Demographic data, history of illness, alarming clinical signs, medications, and outcome of all participants were recorded.Results: Severe asthma exacerbations were more encountered among males, older age, and with a longer duration of asthma (X±SD=28.4±15.9 months) with significant differences when compared to controls. Comparing the studied groups revealed higher risk for severe asthma exacerbations mainly with; history of sudden onset of severe respiratory distress (Odds ratio “OR”=30.13, 95% CI, 13.78-66.69) and chronic steroid-dependent asthma (OR=14.46, 95% CI, 3.97-52.65). Cyanosis, lethargy, and inability to talk were alarming signs in patients with severe asthma exacerbation when compared to those with mild asthma exacerbation (p<0.05).Conclusions: Severe asthma exacerbation in children is still associated with many risk factors that may alert the patients’ caregivers and physicians prospectively for early proper management. 

scholarly journals SOME ASPECTS OF PREDICTING THE SEVERITY OF VIRUS-INDUCED BRONCHIAL ASTHMA EXACERBATION IN CHILDREN DUE TO COVID-19 PANDEMIC

2021 ◽  
Vol 127 (4) ◽  
pp. 99-106
Author(s):  
Dorin Huzun ◽  
Uliana Kostiv ◽  
Serhii Sazhyn ◽  
Alla Sazhyna ◽  
Koliesnik Dmytro Koliesnik
Keyword(s):  
Severe Asthma ◽  
Bronchial Asthma ◽  
Asthma Exacerbation ◽  
Late Onset ◽  
Antiviral Treatment ◽  
Temporary Increase ◽  
Severe Exacerbation ◽  
Physical Analysis ◽  
Asthma Attack ◽  
Β2 Agonists

bronchial asthma is an important medical and social issue directly affects the health of patients, their quality of life, and the direct and indirect economic costs associated with the disease are quite significant. Due to the pandemic caused by a new strain of coronavirus SARS-CoV-2, international and domestic regulations documents have updated the management of patients with asthma. In particular, there have been recommendations for remote visits to assess the patients’ complaints however physical analysis and objective examination are not available during such consultations. It can lead to errors in diagnostic of asthma exacerbation severity and treatment tactic for prescription the reliever therapy. So it is actuality to find out additional indicators to improve the diagnostic and prediction of the severity of the disease exacerbations. Given the urgency of the problem, the aim of the study is to evaluate the clinical and paraclinical parameters in children with virus-induced bronchial asthma exacerbation to predict the severity of the asthma attack and personify the management of patients. Have been examined 47 patients who were hospitalized for disease exacerbation. The severity of a asthma attack was considered a group-forming feature. Statistical analysis was performed using parametric and nonparametric calculation methods, methods of clinical epidemiology and biostatistics. The results of the study give grounds to predict a more severe asthma attack among urban residents who have a phenotype of late-onset asthma. An additional, anamnestic risk of more severe exacerbation of the disease is body weight at birth, which exceeds 3500 g. Among spirometric indicators the highest prognostic criterion for severe bronchial asthma exacerbation was the general index of bronchodilation, which was 15% and above, as well as the index of bronchodilation at the level of the distal airways with a cut-off point of 30% and above. In the presence of the above risk factors for severe asthma attack on the background of confirmed infection with the coronavirus strain SARS-CoV-2 the patient needs hospitalization, antiviral treatment, increasing the dose of inhaled steroids and additional β2-agonists. When predicting a mild or moderate asthma attack provoked by the coronavirus SARS-CoV-2, it is advisable to continue remote monitoring by an allergist and the management of exacerbation includes a temporary increase daily dose of inhaled glucocorticosteroids and additional using of β2-agonists. It is recommended to avoid taking nebulizers and use individual metered powder or aerosol inhalers in cases of inpatient treatment.

Meta-Analysis: Effect of Long-Acting β-Agonists on Severe Asthma Exacerbations and Asthma-Related Deaths

2006 ◽  
Vol 144 (12) ◽  
pp. 904 ◽  
Author(s):  
Shelley R. Salpeter ◽  
Nicholas S. Buckley ◽  
Thomas M. Ormiston ◽  
Edwin E. Salpeter
Keyword(s):  
Severe Asthma ◽  
Meta Analysis ◽  
Asthma Exacerbations ◽  
Long Acting

Influence of β2-adrenergic receptor polymorphisms on asthma exacerbation in children with severe asthma regularly receiving salmeterol

2013 ◽  
Vol 110 (3) ◽  
pp. 156-160 ◽  
Author(s):  
Verónica Giubergia ◽  
Luis Gravina ◽  
Claudio Castaños ◽  
Lilien Chertkoff
Keyword(s):  
Severe Asthma ◽  
Adrenergic Receptor ◽  
Asthma Exacerbation ◽  
Β2 Adrenergic Receptor

Allergic Triggers Associated With More Severe Asthma Exacerbations

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 310A ◽  
Author(s):  
Kathleen A. Sala ◽  
Alex M. Dressler ◽  
Taylor Aglio ◽  
Philip C. Spinella ◽  
Craig M. Schramm ◽  
...  
Keyword(s):  
Severe Asthma ◽  
Asthma Exacerbations
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