scholarly journals Impact of Removing Nonprescription Codeine in Australia: Protocol for a Prospective Cohort Study (Preprint)

2019 ◽  
Author(s):  
Jacqui McCoy ◽  
Suzanne Nielsen ◽  
Raimondo Bruno

BACKGROUND On February 1, 2018, Australia rescheduled codeine to a prescription-only medication. Many concerns were associated with this change, including increased financial costs, reduced service accessibility, the potential for poorer pain management, and a decline in physical and mental health if codeine could not be accessed. In the research literature, there is limited knowledge about the long-term consequences of rescheduling pharmaceutical opioids and, as Australia has followed many countries in implementing a restriction on codeine, further study of these consequences is critical. OBJECTIVE The goal of this study was to examine the impact of rescheduling codeine from an over-the-counter (OTC) product to a prescription-only medicine on the primary measures of codeine use and dependence in a prospective cohort of people who are frequent consumers of OTC codeine. Secondary measures included pain and self-efficacy, health service use, and mental health. METHODS The Codeine Cohort study aimed to recruit 300 participants in Australia who regularly (at least a few times per week for the past 6 months) used OTC codeine. Using an online survey, participants were followed up at three time points (February 2018, June 2018, and February 2019) after codeine was rescheduled. RESULTS All four waves of data collection are complete, with the final round of data collection finalized in August 2019. Data analyses are yet to be completed. Information on demographics, codeine use and dependence, physical and mental health, medication use, and health service use will be analyzed using mixed models. CONCLUSIONS Results of this study will provide insight into the effectiveness of regulatory restriction in curtailing nonmedical use of and harms associated with codeine. Additionally, results will explore positive and negative outcomes of codeine rescheduling for individual patients, which informs health professionals who support patients who use codeine and further community education. INTERNATIONAL REGISTERED REPORT DERR1-10.2196/15540

10.2196/15540 ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. e15540
Author(s):  
Jacqui McCoy ◽  
Suzanne Nielsen ◽  
Raimondo Bruno

Background On February 1, 2018, Australia rescheduled codeine to a prescription-only medication. Many concerns were associated with this change, including increased financial costs, reduced service accessibility, the potential for poorer pain management, and a decline in physical and mental health if codeine could not be accessed. In the research literature, there is limited knowledge about the long-term consequences of rescheduling pharmaceutical opioids and, as Australia has followed many countries in implementing a restriction on codeine, further study of these consequences is critical. Objective The goal of this study was to examine the impact of rescheduling codeine from an over-the-counter (OTC) product to a prescription-only medicine on the primary measures of codeine use and dependence in a prospective cohort of people who are frequent consumers of OTC codeine. Secondary measures included pain and self-efficacy, health service use, and mental health. Methods The Codeine Cohort study aimed to recruit 300 participants in Australia who regularly (at least a few times per week for the past 6 months) used OTC codeine. Using an online survey, participants were followed up at three time points (February 2018, June 2018, and February 2019) after codeine was rescheduled. Results All four waves of data collection are complete, with the final round of data collection finalized in August 2019. Data analyses are yet to be completed. Information on demographics, codeine use and dependence, physical and mental health, medication use, and health service use will be analyzed using mixed models. Conclusions Results of this study will provide insight into the effectiveness of regulatory restriction in curtailing nonmedical use of and harms associated with codeine. Additionally, results will explore positive and negative outcomes of codeine rescheduling for individual patients, which informs health professionals who support patients who use codeine and further community education. International Registered Report Identifier (IRRID) DERR1-10.2196/15540


2016 ◽  
Vol 42 (4) ◽  
pp. 688-700 ◽  
Author(s):  
Minsun Lee ◽  
David Takeuchi ◽  
Zvi Gellis ◽  
Philip Kendall ◽  
Lin Zhu ◽  
...  

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Jane Fisher ◽  
Karen Wynter ◽  
Karin Hammarberg ◽  
John McBain ◽  
Frances Gibson ◽  
...  

2016 ◽  
Vol 47 (1) ◽  
pp. 127-135 ◽  
Author(s):  
S. Evans-Lacko ◽  
R. Takizawa ◽  
N. Brimblecombe ◽  
D. King ◽  
M. Knapp ◽  
...  

BackgroundResearch supports robust associations between childhood bullying victimization and mental health problems in childhood/adolescence and emerging evidence shows that the impact can persist into adulthood. We examined the impact of bullying victimization on mental health service use from childhood to midlife.MethodWe performed secondary analysis using the National Child Development Study, the 1958 British Birth Cohort Study. We conducted analyses on 9242 participants with complete data on childhood bullying victimization and service use at midlife. We used multivariable logistic regression models to examine associations between childhood bullying victimization and mental health service use at the ages of 16, 23, 33, 42 and 50 years. We estimated incidence and persistence of mental health service use over time to the age of 50 years.ResultsCompared with participants who were not bullied in childhood, those who were frequently bullied were more likely to use mental health services in childhood and adolescence [odds ratio (OR) 2.53, 95% confidence interval (CI) 1.88–3.40] and also in midlife (OR 1.30, 95% CI 1.10–1.55). Disparity in service use associated with childhood bullying victimization was accounted for by both incident service use through to age 33 years by a subgroup of participants, and by persistent use up to midlife.ConclusionsChildhood bullying victimization adds to the pressure on an already stretched health care system. Policy and practice efforts providing support for victims of bullying could help contain public sector costs. Given constrained budgets and the long-term mental health impact on victims of bullying, early prevention strategies could be effective at limiting both individual distress and later costs.


2021 ◽  
Vol 15 (1) ◽  
pp. 1-33
Author(s):  
Candice Bowman ◽  
Grace Branjerdporn ◽  
Kathryn Turner ◽  
Memunatu Kamara ◽  
Nischal Tyagi ◽  
...  

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