scholarly journals Fat-Water Interface on Susceptibility-Weighted Imaging and Gradient-Echo Imaging: Comparison of Phantoms to Intracranial Lipomas

2013 ◽  
Vol 201 (4) ◽  
pp. 902-907 ◽  
Author(s):  
Taha M. Mehemed ◽  
Akira Yamamoto ◽  
Tomohisa Okada ◽  
Mitsunori Kanagaki ◽  
Yasutaka Fushimi ◽  
...  
2021 ◽  
pp. 135245852199965
Author(s):  
Kedar R Mahajan ◽  
Moein Amin ◽  
Matthew Poturalski ◽  
Jonathan Lee ◽  
Danielle Herman ◽  
...  

Objective: Describe magnetic resonance imaging (MRI) susceptibility changes in progressive multifocal leukoencephalopathy (PML) and identify neuropathological correlates. Methods: PML cases and matched controls with primary central nervous system lymphoma (PCNSL) were retrospectively identified. MRI brain at 3 T and 7 T were reviewed. MRI-pathology correlations in fixed brain autopsy tissue were conducted in three subjects with confirmed PML. Results: With PML ( n = 26 total, n = 5 multiple sclerosis natalizumab-associated), juxtacortical changes on susceptibility-weighted imaging (SWI) or gradient echo (GRE) sequences were noted in 3/3 cases on 7 T MRI and 14/22 cases (63.6%) on 1.5 T or 8/22 (36.4%) 3 T MRI. Similar findings were only noted in 3/25 (12.0%) of PCNSL patients (odds ratio (OR) 12.83, 95% confidence interval (CI), 2.9–56.7, p < 0.001) on 1.5 or 3 T MRI. On susceptibility sequences available prior to diagnosis of PML, 7 (87.5%) had changes present on average 2.7 ± 1.8 months (mean ± SD) prior to diagnosis. Postmortem 7 T MRI showed SWI changes corresponded to areas of increased iron density along the gray–white matter (GM-WM) junction predominantly in macrophages. Conclusion: Susceptibility changes in PML along the GM-WM junction can precede noticeable fluid-attenuated inversion recovery (FLAIR) changes and correlates with iron accumulation in macrophages.


1994 ◽  
Vol 23 (8) ◽  
pp. 607-610 ◽  
Author(s):  
M. Vahlensieck ◽  
Ph. Lang ◽  
K. Seelos ◽  
D. Yang-Ho Sze ◽  
S. Grampp ◽  
...  

1996 ◽  
pp. 167-213
Author(s):  
Marinus T. Vlaardingerbroek ◽  
Jacques A. den Boer

2019 ◽  
Vol 67 (5) ◽  
pp. 1374
Author(s):  
BrianD Moseley ◽  
JonathanH Smith ◽  
RadhikaR Dhamija ◽  
LyellK Jones

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