EFFECT OF A STAINLESS STEEL MESH SKULL PROSTHESIS ON THE DEPTH DOSE DISTRIBUTION OF 200 kv. ROENTGEN RAYS, CO60, AND HIGH ENERGY ELECTRON BEAMS

1966 ◽  
Vol 96 (1) ◽  
pp. 137-140 ◽  
Author(s):  
G. P. TOSI ◽  
F. COLUMELLA ◽  
G. B. DELZANNO ◽  
G. GAIST ◽  
G. PIAZZA
2009 ◽  
Vol 34 (1) ◽  
pp. 4 ◽  
Author(s):  
Abdelkader Toutaoui ◽  
Nadia Khelassi-Toutaoui ◽  
Zakia Brahimi ◽  
AhmedChafik Chami

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Karolina Kokurewicz ◽  
Enrico Brunetti ◽  
Alessandro Curcio ◽  
Davide Gamba ◽  
Luca Garolfi ◽  
...  

AbstractVery high energy electron (VHEE) beams have been proposed as an alternative radiotherapy modality to megavoltage photons; they penetrate deeply without significant scattering in inhomogeneous tissue because of their high relativistic inertia. However, the depth dose distribution of a single, collimated VHEE beam is quasi-uniform, which can lead to healthy tissue being overexposed. This can be largely overcome by focusing the VHEE beam to a small spot. Here, we present experiments to demonstrate focusing as a means of concentrating dose into small volumetric elements inside a target. We find good agreement between measured dose distributions and Monte Carlo simulations. Focused radiation beams could be used to precisely target tumours or hypoxic regions of a tumour, which would enhance the efficacy of radiotherapy. The development of new accelerator technologies may provide future compact systems for delivering these focused beams to tumours, a concept that can also be extended to X-rays and hadrons.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
L. Whitmore ◽  
R. I. Mackay ◽  
M. van Herk ◽  
J. K. Jones ◽  
R. M. Jones

AbstractThis paper presents the first demonstration of deeply penetrating dose delivery using focused very high energy electron (VHEE) beams using quadrupole magnets in Monte Carlo simulations. We show that the focal point is readily modified by linearly changing the quadrupole magnet strength only. We also present a weighted sum of focused electron beams to form a spread-out electron peak (SOEP) over a target region. This has a significantly reduced entrance dose compared to a proton-based spread-out Bragg peak (SOBP). Very high energy electron (VHEE) beams are an exciting prospect in external beam radiotherapy. VHEEs are less sensitive to inhomogeneities than proton and photon beams, have a deep dose reach and could potentially be used to deliver FLASH radiotherapy. The dose distributions of unfocused VHEE produce high entrance and exit doses compared to other radiotherapy modalities unless focusing is employed, and in this case the entrance dose is considerably improved over existing radiations. We have investigated both symmetric and asymmetric focusing as well as focusing with a range of beam energies.


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