Ultrasound changes of the varicose veins of the lower extremities against connective tissue dysplasia

In recent years medical practitioners more often pay their attention on role of pathology of different organs and systems of human’s body which are associated with connective tissue dysplasia. The importance of this problem is caused by the great prevalence of connective tissue dysplasia, systemacity of damage, high probability of different diseases’ formation. Connective tissue dysplasia is the violation of the connective tissue structure during embryonic and postnatal periods because of genetically modified fibrillogenesis of extracellular matrix, leading to homeostasis disorder on tissue and organ levels with the progressive course. There was held the clinical neurological examination with 120 patients, who had neurological features of vertebral syndrome of lumbosacral spine. Analysis of the clinical examination results demonstrated that patients with vertebral syndrome of lumbosacral spine (p<0,05) more common can occur pathology of joints and varicose veins of the lower extremities. Significantly (p<0,05) (scoliosis, kyphosis, kyphoscoliosis, tendency to dislocation, stretching the ligaments) increase the duration of treatment and the expression of a pain syndrome. The results of examination and monitoring of patients in the dynamics of the treatment showed that patients with vertebral syndrome of lumbosacral spine (p<0,05) more often have anatomical changes in the lumbosacral spine than patients without evidence of DST.

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Morphological signs of connective tissue dysplasia as predictors of frequent post-exercise musculoskeletal disorders

BMC Musculoskeletal Disorders ◽

10.1186/s12891-020-03698-0 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

V. N. Nikolenko ◽

M. V. Oganesyan ◽

A. D. Vovkogon ◽

Yu Cao ◽

A. A. Churganova ◽

...

Keyword(s):

Connective Tissue ◽

Musculoskeletal Disorders ◽

Varicose Veins ◽

Morphological Characteristics ◽

Control Group ◽

Post Exercise ◽

Connective Tissue Dysplasia ◽

Physiological Evaluation ◽

Severe Degree ◽

Study Participants

Abstract Background Connective tissue dysplasia (CTD) is a risk factor for musculoskeletal disorders. Changes caused by disorganization of collagen and elastin fibers lead to the inability of withstanding heavy mechanical stress. In clinical practice, diagnosis of these disorders depends on physical and anthropomorphic evaluation. Methods Forty-eight patients with frequent post-exercise musculoskeletal disorders were evaluated for CTD. The control group included 36 healthy participants. Both groups were evaluated via therapeutic examination with assessment of anthropometric indicators and physical-physiological evaluation, surveying and gathering of anamnesis. Based on testing results, study participants were evaluated on CTD presence and risk factors. Results All experimental group patients had connective tissue dysplasia of moderate and severe degree, with a total score of 49.44 ± 13.1. Certain morphological characteristics showed prevalence, allowing to determine pathognomonic predictors of high predisposition to frequent post-exercise musculoskeletal disorders. Back pain (100%), asthenic syndrome and kyphotic spinal deformation (75%), high gothic palate, hypermobility of joints and the auricles, excessive elasticity (63%), varicose veins of the lower extremities (56%) and hemorrhoids (56%), changes in the shape of the legs and temporomandibular joint (50%) showed to be significant clinical factors indicating possible connective tissue dysplasia. Conclusions The presence of these diagnostically significant morphological signs of CTD in humans is a pathognomonic predictor of a high predisposition to frequent injuries. Their early detection helps promote proper appointment of adequate physical activity regimen and develop treatment for the underlying cause.

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Features of blood vessels in children with connective tissue dysplasia of heart

Practical medicine ◽

10.32000/2072-1757-2020-6-101-105 ◽

2020 ◽

Vol 18 (6) ◽

pp. 101-105

Author(s):

E. Yu. ISAKOVA ◽

◽

T. Yu. ATAMANOVA ◽

Keyword(s):

Connective Tissue ◽

Doppler Ultrasound ◽

Venous Insufficiency ◽

Vascular Diseases ◽

Lower Extremities ◽

Constant Thickness ◽

Saphenous Veins ◽

Upper And Lower Extremities ◽

Connective Tissue Dysplasia ◽

Arteries And Veins

The article presents the results of a study of Doppler ultrasound (USDG) of arteries and veins of the upper and lower extremities of 68 children with connective tissue dysplasia of heart. When examining the veins, functional tests were carried out: Valsalva’s test and a test with compression by a sensor. In children with connective tissue dysplasia of heart and concomitant arterial hypertension, the failure of the valves of saphenous veins is more common. Also, the following pathologies are revealed: chronic venous insufficiency, angiodysplasia, congenital hypoplasia and aplasia of the deep veins of the lower extremities. Examination of the arteries revealed a spasm of the arteries of the upper and lower extremities with a constant thickness of intima-media, Raynaud’s syndrome. In such patients, the linear blood flow velocity decreases, mainly in the deep arteries of the upper and lower extremities. Doppler ultrasound should be used for early detection of changes in the arteries and veins of the upper and lower extremities in order to prevent and treat vascular diseases.

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NON-SPECIFIC CONNECTIVE TISSUE DYSPLASIA – A RISK FACTOR FOR POSTOPERATIVE THROMBOSIS IN THE VENOUS SYSTE M OF LOWER EXTREMITIES

Health Problems of Civilization ◽

10.5114/hpc.2016.59633 ◽

2016 ◽

Vol 2 ◽

pp. 51-54 ◽

Cited By ~ 1

Author(s):

Ihor Venher ◽

Sviatoslav Kostiv ◽

Inna Nenashko

Keyword(s):

Risk Factor ◽

Connective Tissue ◽

Lower Extremities ◽

Postoperative Thrombosis ◽

Connective Tissue Dysplasia

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Signs of connective tissue dysplasia in women with genital prolapse

Obstetrics Gynecology and Reproduction ◽

10.17749/2313-7347/ob.gyn.rep.2021.124 ◽

2021 ◽

Vol 15 (1) ◽

pp. 32-40

Author(s):

A. S. Ustyuzhina ◽

M. A. Solodilova ◽

A. V. Polonikov ◽

S. P. Pakhomov ◽

U. G. Shokirova

Keyword(s):

Pelvic Organ Prolapse ◽

Connective Tissue ◽

Varicose Veins ◽

Genital Prolapse ◽

Pelvic Organ ◽

Main Group ◽

Control Group ◽

Systematic Analysis ◽

Healthy Women ◽

Connective Tissue Dysplasia

Introduction. Despite a long history of the disease, genital prolapse still have not been definitively solved. A relevance of pelvic organ prolapse in women has been increasing in recent years largely due to a change in the quality of life and desire to sustain their youth. The number of studies pinpointing the cause of the disease in connective tissue dysplasia (CTD) has been increasing annually.Aim: to conduct a systematic analysis and determine most common signs of CTD in women with genital prolapse.Materials and methods. CTD criteria and the relationship with genital prolapse were analyzed. The study was conducted using questionnaires and including clinical studies examining residents of the Belgorod region (135 women). The main group included 91 patients who had signs of pelvic organ prolapse, and control group consisted of 44 healthy women. CTD intensity score proposed by T.Yu. Smolnova et al. (2003) was used to assess signs of dysplasia in women examined allowing to build up three groups in which each symptom was evaluated as severity score.Results. Asthenic constitution was noted in high percentage of women suffering from genital prolapse (16.70 ± 0.38 %) compared with healthy women (2.30 ± 0.15 %; p = 0.016). Mild bruising, increased tissue bleeding tended to rise in main vs. control group (16.50 ± 0.37 % in main group and 0.0 in control group; p = 0.016). Signs of varicose veins and hemorrhoids requiring no surgical treatment were found in 33.00 ± 0.47 % and 4.50 ± 0.21 % in main vs. control group (p = 0.0002), respectively. Genital prolapse and hernia in first-line relatives were recorded in 9.90 ± 0.30 % in main group (p = 0.031), women without signs of prolapse did not indicate prolapse in close relatives.Conclusion. Asthenic constitution, hernias, varicose veins and hemorrhoids, female pelvic and hernial prolapse in close female relatives, a tendency to mild bruising, skeletal anomalies, elastosis skin were among common CTD signs in women with genital prolapse.

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