Undifferentiated Connective Tissue Dysplasia As a Risk Factor of Superficial Thrombophlebitis in Patients with Varicose Veins

Flebologiia ◽  
2021 ◽  
Vol 15 (4) ◽  
pp. 279
Author(s):  
O.A. Tsarev ◽  
F.G. Prokin ◽  
N.N. Zakharov ◽  
A.Yu. Anisimov ◽  
Yu.V. Mashchenko ◽  
...  
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Varicose Veins ◽  
Superficial Thrombophlebitis ◽  
Connective Tissue Dysplasia

The Displays of Connective Tissue Dysplasia (Hypermobility) in Patients with Vertebral Syndrome of Lumbosacral Spine

2016 ◽  
pp. 149-154
Author(s):  
Oleksandr Piantkovskiy
Keyword(s):  
Connective Tissue ◽  
Varicose Veins ◽  
Pain Syndrome ◽  
Lumbosacral Spine ◽  
Duration Of Treatment ◽  
Medical Practitioners ◽  
Clinical Neurological Examination ◽  
Connective Tissue Dysplasia ◽  
Neurological Features

In recent years medical practitioners more often pay their attention on role of pathology of different organs and systems of human’s body which are associated with connective tissue dysplasia. The importance of this problem is caused by the great prevalence of connective tissue dysplasia, systemacity of damage, high probability of different diseases’ formation. Connective tissue dysplasia is the violation of the connective tissue structure during embryonic and postnatal periods because of genetically modified fibrillogenesis of extracellular matrix, leading to homeostasis disorder on tissue and organ levels with the progressive course. There was held the clinical neurological examination with 120 patients, who had neurological features of vertebral syndrome of lumbosacral spine. Analysis of the clinical examination results demonstrated that patients with vertebral syndrome of lumbosacral spine (p<0,05) more common can occur pathology of joints and varicose veins of the lower extremities. Significantly (p<0,05) (scoliosis, kyphosis, kyphoscoliosis, tendency to dislocation, stretching the ligaments) increase the duration of treatment and the expression of a pain syndrome. The results of examination and monitoring of patients in the dynamics of the treatment showed that patients with vertebral syndrome of lumbosacral spine (p<0,05) more often have anatomical changes in the lumbosacral spine than patients without evidence of DST.

scholarly journals Morphological signs of connective tissue dysplasia as predictors of frequent post-exercise musculoskeletal disorders

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
V. N. Nikolenko ◽  
M. V. Oganesyan ◽  
A. D. Vovkogon ◽  
Yu Cao ◽  
A. A. Churganova ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Musculoskeletal Disorders ◽  
Varicose Veins ◽  
Morphological Characteristics ◽  
Control Group ◽  
Post Exercise ◽  
Connective Tissue Dysplasia ◽  
Physiological Evaluation ◽  
Severe Degree ◽  
Study Participants

Abstract Background Connective tissue dysplasia (CTD) is a risk factor for musculoskeletal disorders. Changes caused by disorganization of collagen and elastin fibers lead to the inability of withstanding heavy mechanical stress. In clinical practice, diagnosis of these disorders depends on physical and anthropomorphic evaluation. Methods Forty-eight patients with frequent post-exercise musculoskeletal disorders were evaluated for CTD. The control group included 36 healthy participants. Both groups were evaluated via therapeutic examination with assessment of anthropometric indicators and physical-physiological evaluation, surveying and gathering of anamnesis. Based on testing results, study participants were evaluated on CTD presence and risk factors. Results All experimental group patients had connective tissue dysplasia of moderate and severe degree, with a total score of 49.44 ± 13.1. Certain morphological characteristics showed prevalence, allowing to determine pathognomonic predictors of high predisposition to frequent post-exercise musculoskeletal disorders. Back pain (100%), asthenic syndrome and kyphotic spinal deformation (75%), high gothic palate, hypermobility of joints and the auricles, excessive elasticity (63%), varicose veins of the lower extremities (56%) and hemorrhoids (56%), changes in the shape of the legs and temporomandibular joint (50%) showed to be significant clinical factors indicating possible connective tissue dysplasia. Conclusions The presence of these diagnostically significant morphological signs of CTD in humans is a pathognomonic predictor of a high predisposition to frequent injuries. Their early detection helps promote proper appointment of adequate physical activity regimen and develop treatment for the underlying cause.

scholarly journals Connective tissue dysplasia: a risk factor for osteopenia in children and adolescents

2020 ◽  
pp. 30-40
Author(s):  
I. N. Zakharova ◽  
T. M. Tvorogova ◽  
E. А. Solov’yeva ◽  
L. L. Stepurina ◽  
A. S. Vorob’yeva
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Children And Adolescents ◽  
Connective Tissue Dysplasia

scholarly journals Connective tissue dysplasia as a risk factor complicated course of surgical diseases knee in children

2016 ◽  
Vol 11 (2) ◽  
Author(s):  
Vladimir Murga ◽  
Vladimir Krestyashin ◽  
Leonid Rasskazov ◽  
Galina Rumyantseva ◽  
Vladimir Kartashev
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Complicated Course ◽  
Connective Tissue Dysplasia

scholarly journals Connective tissue dysplasia syndrome as a risk factor of severe course of bronchial obstruction syndrome in children

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Natalia Fedko ◽  
Angelina Kalmykova ◽  
Natalia Lagodina ◽  
Valentina Muravyeva ◽  
Asiyat Dzhanibekova ◽  
...  
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Bronchial Obstruction ◽  
Connective Tissue Dysplasia

scholarly journals Undifferentiated connective tissue dysplasia as a predictor of heart rate disorders in combination with gastroesophageal reflux disease in children

2021 ◽  
pp. 41-45
Author(s):  
Oksana Herasymova ◽  
Tetiana Filonova
Keyword(s):  
Risk Factor ◽  
Gastroesophageal Reflux Disease ◽  
Connective Tissue ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Study Groups ◽  
Group Iii ◽  
Group I ◽  
Connective Tissue Dysplasia ◽  
Tooth Growth

The aim: to improve the early diagnosis of arrhythmia in combination with gastroesophageal reflux disease (GERD) in children, by studying the risk of connective tissue dysplasia on the occurrence of this pathology. Materials and methods. We examined 100 children aged 8 to 18 years, mean age 13.7±2.7 years, of which 32 children with arrhythmias without combined pathology were group I, 36 children with concomitant GERD - group II and 32 children with GERD without concomitant arrhythmias - group III. Patients underwent clinical and instrumental studies (electrocardiography, Holter daily ECG monitoring, esophagogastroduodenoscopy and pH-metry) and evaluation of phenotypic signs of NDST according to the criteria of T. Milkovskaya-Dimitrova and A. Karkasho. Results. A risk factor for the formation of combined pathology in children in the form of arrhythmia and GERD was identified, namely the next main phenotypic feature of NDST (undifferentiated connective tissue dysplasia) – dysplastic tooth growth. Also, predictors of both an isolated variant of arrhythmia in children and arrhythmia in combination with GERD – high height and scoliotic posture were identified. In this case, the risk factor for an isolated variant of arrhythmia in children, according to the results of the study is asthenic constitution. The severity of NDST in the studied groups was determined. The analysis of the results revealed the absence of a statistically significant relationship between the severity of NDST and study groups, although it should be noted that in children of group III the first degree of NDST was not observed in general. Conclusions. It was found that asthenic constitution, dysplastic tooth growth, tall stature and scoliotic posture are statistically significant risk factors for the development of the studied pathologies. There were no statistically significant differences between the study groups regarding the severity of NDST, but there was a complete lack of detection in children of group III (children with isolated GERD without concomitant arrhythmia) of the first degree of NDST

scholarly journals Signs of connective tissue dysplasia in women with genital prolapse

2021 ◽  
Vol 15 (1) ◽  
pp. 32-40
Author(s):  
A. S. Ustyuzhina ◽  
M. A. Solodilova ◽  
A. V. Polonikov ◽  
S. P. Pakhomov ◽  
U. G. Shokirova
Keyword(s):  
Pelvic Organ Prolapse ◽  
Connective Tissue ◽  
Varicose Veins ◽  
Genital Prolapse ◽  
Pelvic Organ ◽  
Main Group ◽  
Control Group ◽  
Systematic Analysis ◽  
Healthy Women ◽  
Connective Tissue Dysplasia

Introduction. Despite a long history of the disease, genital prolapse still have not been definitively solved. A relevance of pelvic organ prolapse in women has been increasing in recent years largely due to a change in the quality of life and desire to sustain their youth. The number of studies pinpointing the cause of the disease in connective tissue dysplasia (CTD) has been increasing annually.Aim: to conduct a systematic analysis and determine most common signs of CTD in women with genital prolapse.Materials and methods. CTD criteria and the relationship with genital prolapse were analyzed. The study was conducted using questionnaires and including clinical studies examining residents of the Belgorod region (135 women). The main group included 91 patients who had signs of pelvic organ prolapse, and control group consisted of 44 healthy women. CTD intensity score proposed by T.Yu. Smolnova et al. (2003) was used to assess signs of dysplasia in women examined allowing to build up three groups in which each symptom was evaluated as severity score.Results. Asthenic constitution was noted in high percentage of women suffering from genital prolapse (16.70 ± 0.38 %) compared with healthy women (2.30 ± 0.15 %; p = 0.016). Mild bruising, increased tissue bleeding tended to rise in main vs. control group (16.50 ± 0.37 % in main group and 0.0 in control group; p = 0.016). Signs of varicose veins and hemorrhoids requiring no surgical treatment were found in 33.00 ± 0.47 % and 4.50 ± 0.21 % in main vs. control group (p = 0.0002), respectively. Genital prolapse and hernia in first-line relatives were recorded in 9.90 ± 0.30 % in main group (p = 0.031), women without signs of prolapse did not indicate prolapse in close relatives.Conclusion. Asthenic constitution, hernias, varicose veins and hemorrhoids, female pelvic and hernial prolapse in close female relatives, a tendency to mild bruising, skeletal anomalies, elastosis skin were among common CTD signs in women with genital prolapse.

scholarly journals CONNECTIVE TISSUE DYSPLASIA AS A POTENTIAL RISK FACTOR FOR MYOCARDIAL ELECTRIC INSTABILITY IN YOUNG ATHLETES

2020 ◽  
Vol 19 (4) ◽  
pp. 125-132 ◽  
Author(s):  
V Timokhina ◽  
K Mekhdieva ◽  
F Blyakhman
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Respiratory System ◽  
Recovery Time ◽  
Stress Test ◽  
Physical Exertion ◽  
National Guidelines ◽  
Young Athletes ◽  
System Adaptation ◽  
Connective Tissue Dysplasia

The proposed study was focused on search for the potential interrelations between the degree of connective tissue dysplasia (CTD) and efficiency of cardio-respiratory system adaptation to load in young athletes. Materials and methods. Parameters of cardio-respiratory system were evaluated in 200 athletes aged from 11 to 23 years with the use of cycling spiroergometry and 12-lead ECG at rest, during and after stress test. The degree of connective tissue dysplasia was assessed as per the score scale of National Guidelines. Results. It was revealed that 86% of studied athletes had moderate or marked degree of system CTD. Generally, CTD limited athletes’ cardio-respiratory system adaptation to load and was associated with myocardium repolarization disorders. Conclusion. The results of this study demonstrated that athletes with CTD showed certain changes in the electrical activity of the heart at rest and during physical exertion. Athletes with CTD compared to athletes without dysplasia have initially lower economization of the cardiovascular system and a significantly longer recovery time after exercise. This means that CTD limits the mobilization of CRS for adaptation to load, especially if the loads are cyclical.

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