Evaluation of hematological parameters related to systemic inflammation in acute and subacute/chronic low back pain

2021 ◽  
Author(s):  
Okan Günaydın ◽  
Elzem Bolkan Günaydın
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Systemic Inflammation ◽  
Hematological Parameters ◽  
Diagnostic Value ◽  
Low Back ◽  
Red Cell ◽  
Cell Distribution ◽  
Pain Group ◽  
Distribution Width

Aim: To compare the hematological parameters associated with systemic inflammation between acute and subacute/chronic nonspecific low back pain and to evaluate their diagnostic roles in relation to chronicity in low back pain. Materials & methods: This retrospective case–control study included 150 participants aged 18–65 years with acute nonspecific low back pain, 150 with subacute/chronic nonspecific low back pain, 150 as the control group. Results: Red cell distribution width was significantly higher in the subacute/chronic pain group compared with the acute pain group (p = 0.003), and had a poor diagnostic value for chronicity (Cutoff: 11.95, p = 0.003). There were no significant differences in terms of other parameters (p > 0.05). Conclusion: Red cell distribution width has a poor diagnostic value for chronicity in nonspecific low back pain.

Nonspecific Chronic Low Back Pain in Elderly Patients

2021 ◽  
pp. 34
Author(s):  
Amal Mowafy
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Muscle Mass ◽  
Control Group ◽  
P Value ◽  
Low Back ◽  
Cell Distribution ◽  
Distribution Width ◽  
X Ray ◽  
Red Blood Cell Distribution

Introduction: Low back pain is one of the most common causes of disabilities in old people often due to lumber degeneration (osteoarthritis) and spinal canal stenosis. In our study, we determine the prevalence and associated changes of low back pain that increase with age. Methodology: This observational cohort study was carried out from March 2019 to March 2021 at the El-Moussenin Center in Port Said. The study included 300 patients aged ≥65 years with a chronic nonspecific low back pain for at least six months, a Visual Analogue Scale (VAS) score of 3 and more, and an absence of spinal pathology such as infection, tumor, fracture, spondylolisthesis, or spinal degeneration of grade 2 and above. Patients were divided into two groups: (i) a study group including patients with a mean age of 75 years with nonspecific chronic LBP (n = 150) and (ii) an age- and sex-matched control group (n = 150) with no chronic low back pain using propensity score-matched analysis. All patients underwent whole spinal X-ray, lumbar MRI, CBC, and DXA. Result: We analyzed laboratory finding, radiological finding for global spinal parameter, and lumber degeneration body composition analysis using whole body dual energy X-ray absorptiometry. We found increase in red blood cell distribution width (it is an index of aging), it was higher in geriatric with CLBP (32) and in control (6.9) with a p-value < 0.001. Skeletal muscle mass index was 6.23 ± 0.92 in the studied group and 6.43 ± 1.02 in the control group with a p-value = 0.045. Increase in fat mass was noted in both the studied (32.17 ± 7.07) and the control (29.28 ± 7.48) groups with a p-value < 0.001. Moreover, those patients had lower lumbar lordosis, higher sagittal vertical axis regarding decrease in muscle mass in trunk and extremities. Conclusion: Red blood cell distribution width which is a sign of aging was high in geriatric group with CLBP. Moreover, geriatric CLBP is often associated with osteoporosis which affects the pain threshold and triggers CLBP due to age-related loss of skeletal muscle mass and spinal sagittal malalignment.

A Comparison of Lumbar Lordosis in Asymptomatic and Low back pain group

1995 ◽  
Vol 30 (1) ◽  
pp. 83
Author(s):  
Hak Jin Min ◽  
Keun Woo Kim ◽  
Pil Gu Lee ◽  
Yong Hoon Kim ◽  
Ui Seoung Yoon ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Lordosis ◽  
Low Back ◽  
Pain Group

Study of the Feasibility of Conventional MR Images and Magnetic Resonance (MR)/Ultra-Short Echo Time (UTE) Technique in the Evaluation of Lumbar Disc Degeneration in the Axial Plane

2021 ◽  
Vol 11 (3) ◽  
pp. 817-821
Author(s):  
Peng Tang ◽  
Jingtao Xu ◽  
Wei Liu ◽  
Yu Li ◽  
Wei Fan ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Structural Integrity ◽  
Low Back ◽  
Pain Group ◽  
Cartilage Endplate ◽  
Significant Difference

The advantage and value of magnetic resonance (MR)-ultra-short echo time (UTE) technique in the displaying the structures of degenerative intervertebral discs were observed through evaluating the lumbar disc degeneration in the axial plane by conventional MR image and MR-UTE technique. A total of 160 examinees screened by inclusion and exclusion criteria were enrolled, and a total of 800 intervertebral disks were involved, and the degree of intervertebral disc degeneration was classified by conventional MR image classification method. After the first echo image of MR-UTE technique was integrated with the contour, the image entered UTE cartilage endplate, fibrous ring and osseous endplate. The integrity of the intervertebral disc from the above and below the intervertebral disc and the correlation of the structural endplate with the integrities of cartilage endplate, fibrous ring and osseous endplate under double echo sequence were analyzed, and the correlation analysis of the two categorical variables was conducted using rank correlation analysis. Under the MR-UTE sequence, there was no statistical significant difference in structural integrity constituent ratio (intact structure only on one side, incomplete structure on both side) between the non-low back pain group and the low back pain group (P > 0.05), the proportion of complete structure disappearance was lowest, and the proportion of partial structure disappearance was highest; there was a significant difference in the structural integrity of fibrous ring between the non-low back pain group and the low back pain group (P < 0.05), there was a statistical significant difference in structural integrity of fibrous rings between the two groups (P < 0.05); there was a statistical significant difference in pain degree between the partial structure disappearance group and the complete structure disappearance group (P < 0.05). There was no significant difference in pain degree between the groups (intact structure only on one side and incomplete structure on both side); conventional MR images showed no significant difference in the intervertebral disc degeneration degree between the non-low back pain group and low back pain group (P > 0.05), and the intervertebral disc degeneration degree had no significant correlation with the lower back pain. MR-UTE sequence and T2WI sequence showed that there was a correlation between different intervertebral disc degeneration degrees and the structural integrity distributions of cartilage endplate, osseous endplate and fibrous rings in two groups of patients with or without low back pain (P < 0.05). Whether low back pain exists or not has little effect on the intervertebral disc degeneration degree on T2WI. MR-UTE double echo sequence scan reveals that the intervertebral disc degeneration degree is positively related to the integrity and integrity distribution of cartilage endplate, fibrous ring and bone endplate.

The diagnostic value of bone scintigraphy in patients with low back pain

1983 ◽  
Vol 10 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Henri E. Sch�tte ◽  
William M. Park
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Bone Scintigraphy ◽  
Diagnostic Value ◽  
Low Back

scholarly journals Comparison of Low Back Pain Recovery and Persistence

2016 ◽  
Vol 18 (4) ◽  
pp. 401-410 ◽  
Author(s):  
Angela R. Starkweather ◽  
Debra E. Lyon ◽  
Patricia Kinser ◽  
Amy Heineman ◽  
Jamie L. Sturgill ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Short Form ◽  
Brief Pain Inventory ◽  
Acute Stage ◽  
Low Back ◽  
Pain Group ◽  
Acute Low Back Pain ◽  
Initial Onset ◽  
Remote Sites

Background: Persistent low back pain is a significant problem worldwide. Early identification and treatment of individuals at high risk for persistent low back pain have been suggested as strategies to decrease the rate of disability associated with this condition. Purpose: To examine and compare demographic, pain-related, psychological, and somatosensory characteristics in a cohort of participants with acute low back pain who later went on to experience persistent low back pain or whose pain resolved within the first 6 weeks after initial onset. Methods: A descriptive study was conducted among men and women 18–50 years of age who had an acute episode of low back pain. Study questionnaires were administered to collect demographic information and measures of pain, coping, reactivity, mood, work history and satisfaction, and disability. A standardized protocol of quantitative sensory testing was performed on each participant at the painful area of their low back and at a remote site on their arm. Results: The sample consisted of 48 participants, of whom 19 went on to develop persistent low back pain and 29 resolved. Compared to the resolved group, the persistent low back pain group was significantly older and had a lower level of educational attainment, a higher body mass index, and higher mean “least” pain score on the Brief Pain Inventory–Short Form. Significantly higher thermal detection thresholds at the painful and remote sites as well as signs of central sensitivity differentiated the persistent pain group from the resolved group during the acute stage of low back pain.

scholarly journals Relationship between Nonspecific Low Back Pain and Physical Function among Japanese High School Long-distance Runners

2021 ◽  
Vol 6 (2) ◽  
pp. p1
Author(s):  
K. Nakagawa ◽  
A. Mitomo ◽  
Y. Takahashi
Keyword(s):  
High School ◽  
Low Back Pain ◽  
Back Pain ◽  
Muscle Strength ◽  
Low Back ◽  
Distance Runners ◽  
Long Distance ◽  
Pain Group ◽  
History Of ◽  
Hip Extension

Background: For long-distance runners, low back pain as well as lower extremity disorders are becoming more common. This study analyzed the relationship between regular physical assessment results and nonspecific low back pain among long-distance runners. Methods: Subjects included 105 high school long-distance runners, who were divided into the low back pain group (n = 20; LP) and non-pain group (n = 85; NP). All subjects underwent regular chronic pain and physical assessments every six months. Differences in each measurement between both groups were analyzed using an unpaired t-test for comparison.Results: The LP had a shorter history of athletics (LP=3.2 years, NP=4.6 years, 95% confidence interval (95%CI): -2.55, -0.28, r=0.45), a greater hip extension angle (LP=32.7°, NP=28.4°, 95% CI: 2.85, 5.61, r=0.67), a lower hip extension muscle strength (LP=3.1 kgf/kg, NP=4.0 kgf/kg, 95% CI; 0.19, 0.61, r=0.45), and a greater number of times during the stand-up test (LP=11.1, NP=8.1, 95% CI; 0.40, 5.56, r=0.45) than the NP.Conclusion: An excessive hip extension angle and insufficient hip extension muscle strength were considered as risk factors. It is possible that the excessive movement of the hip joint and the biarticular muscles may have caused the low back pain in the inexperienced runners.

Lumbar Intervertebral Kinematics During an Unstable Sitting Task and Its Association With Standing-Induced Low Back Pain

2020 ◽  
Vol 36 (6) ◽  
pp. 423-435
Author(s):  
Daniel Viggiani ◽  
Erin M. Mannen ◽  
Erika Nelson-Wong ◽  
Alexander Wong ◽  
Gary Ghiselli ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Spine ◽  
Sagittal Plane ◽  
Control Strategies ◽  
Low Back ◽  
Pain Group ◽  
Video Fluoroscopy ◽  
Anterior Posterior

People developing transient low back pain during standing have altered control of their spine and hips during standing tasks, but the transfer of these responses to other tasks has not been assessed. This study used video fluoroscopy to assess lumbar spine intervertebral kinematics of people who do and do not develop standing-induced low back pain during a seated chair-tilting task. A total of 9 females and 8 males were categorized as pain developers (5 females and 3 males) or nonpain developers (4 females and 5 males) using a 2-hour standing exposure; pain developers reported transient low back pain and nonpain developers did not. Participants were imaged with sagittal plane fluoroscopy at 25 Hz while cyclically tilting their pelvises anteriorly and posteriorly on an unstable chair. Intervertebral angles, relative contributions, and anterior–posterior translations were measured for the L3/L4, L4/L5, and L5/S1 joints and compared between sexes, pain groups, joints, and tilting directions. Female pain developers experienced more extension in their L5/S1 joints in both tilting directions compared with female nonpain developers, a finding not present in males. The specificity in intervertebral kinematics to sex-pain group combinations suggests that these subgroups of pain developers and nonpain developers may implement different control strategies.

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