Imaging of chemotherapy-induced liver toxicity: an illustrated overview

Chemotherapy is a potential cause of focal and diffuse hepatobiliary lesions. Many of these lesions may be demonstrated on imaging, especially computed tomography and MRI. Some of these lesions, especially those of steatosis and sinusoidal obstruction syndrome, are associated with a worse prognosis and risk of hepatic failure in the context of surgical management. Notably, some chemotherapy-induced hepatic alterations, such as sinusoidal obstruction syndrome, pseudocirrhosis and focal hepatopathies, may be mistakenly interpreted as signs of cancer progression, misguiding the therapeutic planning for patients receiving chemotherapy.

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Faculty Opinions recommendation of Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717955250.793460400 ◽

2012 ◽

Author(s):

Ralf Weiskirchen

Keyword(s):

Gap Junction ◽

Fulminant Hepatic Failure ◽

Hepatic Failure ◽

Liver Toxicity ◽

Drug Induced ◽

Gap Junction Inhibition

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Mucocele of appendix: a case report

Journal of the Pakistan Medical Association ◽

10.47391/jpma.01 ◽

2021 ◽

pp. 1-7

Author(s):

Fareeha Farooqui ◽

Sehrish Latif ◽

Humera Naz Altaf ◽

Sania Waseem ◽

Sohaib Khan ◽

...

Keyword(s):

Computed Tomography ◽

Case Report ◽

Gastrointestinal Tract ◽

Surgical Management ◽

Iliac Fossa ◽

Mucinous Cystadenoma ◽

Right Hemicolectomy ◽

Unusual Presentation ◽

Rare Tumor ◽

Malignant Changes

Abstract Mucinous cystadenoma is a rare tumor of appendix it accounts for only 0.4% of the gastrointestinal tract malignancies and is reported rarely in literature. Therefore the surgical management is not yet established. Here we report a case of a 65 year old female who presented with a dragging sensation and a feeling of mass in right iliac fossa. Her computed tomography (CT) suggested an abscess formation of the parietal peritoneum. She was planned for laparotomy and upon exploration a mass was found arising from tip of retroperitoneal appendix. Whole of the appendix was studded with mucoid material. Limited right hemicolectomy was performed and histopathology of appendix showed mucinous cystadenoma with no evidence of malignant changes. Patient remained uneventful and was discharged on 4th post operative day. The unusual presentation of retroperitoneal pseudomyxoma without any intraperitoneal pathology, prompted us to report this case. Continuous...

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The Application of Intraoperative Computed Tomography in Surgical Management of Temporomandibular Joint Ankylosis

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2020.09.002 ◽

2021 ◽

Vol 79 (1) ◽

pp. 90.e1-90.e7

Author(s):

Dongyang Ma ◽

Shumeng Zhang ◽

Chaoyuan Pang ◽

Wenkai Zhang ◽

Bingwu Wang ◽

...

Keyword(s):

Computed Tomography ◽

Temporomandibular Joint ◽

Surgical Management ◽

Intraoperative Computed Tomography ◽

Temporomandibular Joint Ankylosis ◽

Joint Ankylosis

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Contribution of cone-beam computed tomography in the decision of surgical management for bone lesions of the maxillofacial region

Journal of Cranio-Maxillofacial Surgery ◽

10.1016/j.jcms.2018.10.007 ◽

2019 ◽

Vol 47 (1) ◽

pp. 87-92 ◽

Cited By ~ 1

Author(s):

Ananda Amaral Santos ◽

Fernanda Paula Yamamoto-Silva ◽

Erica Miranda Torres ◽

José Valladares-Neto ◽

Paulo Tadeu Souza Figueiredo ◽

...

Keyword(s):

Computed Tomography ◽

Surgical Management ◽

Cone Beam Computed Tomography ◽

Cone Beam ◽

Bone Lesions ◽

Maxillofacial Region

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Pericardial masses and congenital abnormalities

ESC CardioMed ◽

10.1093/med/9780198784906.003.0380 ◽

2018 ◽

pp. 1582-1584

Author(s):

Angelos G. Rigopoulos ◽

Hubert Seggewiss

Keyword(s):

Computed Tomography ◽

Surgical Management ◽

Congenital Abnormalities ◽

Benign Lesions ◽

Chest Computed Tomography ◽

X Ray ◽

Wall Calcification ◽

Chest X Ray ◽

Pericardial Cysts ◽

The Right

Pericardial masses include cysts, pericardial tumours, and pericardial haematomas. Pericardial cysts are benign lesions commonly located in the right cardiophrenic angle that remain typically asymptomatic and are incidentally found in chest X-ray or chest computed tomography but might cause pressure symptoms or become infected, thus requiring surgical management. Hydatid cysts due to echinococcosis are the most common acquired pericardial cysts, characterized by wall calcification, and indicate surgery.

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Mapping of both column acetabular fractures with three-dimensional computed tomography and implications on surgical management

BMC Musculoskeletal Disorders ◽

10.1186/s12891-019-2622-0 ◽

2019 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Yun Yang ◽

Chang Zou ◽

Yue Fang

Keyword(s):

Computed Tomography ◽

Surgical Management ◽

Three Dimensional ◽

Acetabular Fractures

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Acute Liver Failure with Diffuse Liver Metastasis from Breast Cancer, Not Detected by Computed Tomography: 2 Case Reports

Case Reports in Oncology ◽

10.1159/000493848 ◽

2018 ◽

Vol 11 (3) ◽

pp. 699-704 ◽

Cited By ~ 3

Author(s):

Takatsugu Ogata ◽

Yuichiro Kikawa ◽

Misato Ogata ◽

Hironaga Satake ◽

Yukimasa Hatachi ◽

...

Keyword(s):

Breast Cancer ◽

Computed Tomography ◽

Liver Metastasis ◽

Liver Failure ◽

Acute Liver Failure ◽

Hepatic Failure ◽

Poor Prognosis ◽

Alcoholic Hepatitis ◽

Case Reports ◽

History Of

Diffuse liver metastasis is a rare pattern of liver metastasis that is associated with hepatic failure and poor prognosis. We experienced 2 cases of acute liver failure due to diffuse metastasis that could not be detected using computed tomography. In case 1, it was difficult to differentiate diffuse metastasis from alcoholic hepatitis. In case 2, it was difficult to diagnose diffuse liver metastasis because the patient had no history of malignancy. When liver enzyme levels are elevated, it is necessary to consider liver metastasis as a potential cause, regardless of computed tomography findings.

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The Diagnosis and Surgical Management of Intracardiac Quill Foreign Body in a Dog

Journal of the American Animal Hospital Association ◽

10.5326/jaaha-ms-6332 ◽

2016 ◽

Vol 52 (1) ◽

pp. 73-76 ◽

Cited By ~ 4

Author(s):

Daniel Joseph Santiago Nucci ◽

Julius Liptak

Keyword(s):

Computed Tomography ◽

Foreign Body ◽

Right Ventricle ◽

Surgical Management ◽

Foreign Bodies ◽

Cardiac Injury ◽

Median Sternotomy ◽

Good Prognosis ◽

Bilateral Pneumothorax ◽

The Right

A dog was referred to Alta Vista Animal Hospital with a porcupine quill penetrating the right ventricle. The presenting complaint was tachypnea and dyspnea secondary to bilateral pneumothorax. Computed tomography revealed bilateral pneumothorax without evidence of quills. A median sternotomy was performed and the quill was removed. The dog recovered uneventfully. Quill injuries are common in dogs; however, intracardiac quill migration is rare. Dogs without evidence of severe cardiac injury secondary to intracardiac foreign bodies may have a good prognosis.

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