scholarly journals Analysis of pediatric diaphyseal femoral fracture treated with titanium elastic nailing system

2021 ◽  
Vol 7 (4) ◽  
pp. 226-230
Author(s):  
H Shanti Kumar Singh ◽  
Nikhil Juneja ◽  
Yogananda ML
Keyword(s):  
Femoral Fracture ◽  
Titanium Elastic Nailing ◽  
Diaphyseal Femoral Fracture

scholarly journals Diaphyseal femoral fracture due to severe vitamin D3 deficiency and low parathyroid hormone levels on long-term hemodialysis: a case report

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Masaki Hatano ◽  
Izuru Kitajima ◽  
Kazuya Isawa ◽  
Yutaka Hirota ◽  
Tatsuya Suwabe ◽  
...  
Keyword(s):  
Vitamin D ◽  
Femoral Fracture ◽  
Iliac Crest ◽  
Bone Biopsy ◽  
Active Vitamin ◽  
Severe Vitamin ◽  
Active Vitamin D ◽  
Woven Bone ◽  
Diaphyseal Femoral Fracture

Abstract Introduction Currently, there are no reports of diaphyseal femoral fracture equivalent to atypical femoral fractures (AFFs) in patients receiving long-term hemodialysis (HD). Case report A 56-year-old Japanese man receiving long-term HD for 34 years was admitted to our hospital due to a delay in postoperative healing. The patient began maintenance hemodialysis at 22 years of age. The patient then underwent surgical parathyroidectomy (PTX) for secondary hyperparathyroidism at 43 years of age, which resulted in decreased levels of parathyroid hormone (PTH). Thereafter, this patient’s serum 1,25(OH)2 D3 level was very low because active vitamin D3 derivative was not administered. At 54 years of age, a transverse fracture of the femoral shaft equivalent to AFF occurred. Surgery with open reduction and internal fixation using intramedullary nailing was performed; however, the delay of postoperative healing continued for 16 months. A left iliac crest bone biopsy was performed and showed osteoid-like lesion and an increase of woven bone. The patient received active vitamin D3 derivative and recombinant human PTH (1–34) derivative. Twenty-nine months after the first surgery, a reoperation was performed. Simultaneously, a right iliac crest bone biopsy was performed. Bone morphometrical improvement was confirmed. Six months after resurgery, the bone union was achieved. Summary Severe vitamin D3 deficiency and decreased levels of PTH may induce a higher osteoid state and an increase of woven bone, which may then attribute to the development of diaphyseal femoral fracture and impairment of postoperative bone healing. It is hypothesized that treatment with active vitamin D3 and teriparatide acetate may be a therapeutic option via the accelerated formation of lamellar bone for refractory diaphyseal femoral fracture of long-term dialysis.

scholarly journals Biomimetic Composite Coatings for Activation of Titanium Implant Surfaces: Methodological Approach and In Vivo Enhanced Osseointegration

Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1352
Author(s):  
Daniel Oltean-Dan ◽  
Gabriela-Bombonica Dogaru ◽  
Elena-Mihaela Jianu ◽  
Sorin Riga ◽  
Maria Tomoaia-Cotisel ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Femoral Fracture ◽  
Bone Fractures ◽  
Composite Coatings ◽  
Methodological Approach ◽  
Albino Rats ◽  
Sem Images ◽  
Bone Implant ◽  
Bone Implant Contact ◽  
Diaphyseal Femoral Fracture

Innovative nanomaterials are required for the coatings of titanium (Ti) implants to ensure the activation of Ti surfaces for improved osseointegration, enhanced bone fracture healing and bone regeneration. This paper presents a systematic investigation of biomimetic composite (BC) coatings on Ti implant surfaces in a rat model of a diaphyseal femoral fracture. Methodological approaches of surface modification of the Ti implants via the usual joining methods (e.g., grit blasting and acid etching) and advanced physicochemical coating via a self-assembled dip-coating method were used. The biomimetic procedure used multi-substituted hydroxyapatite (ms-HAP) HAP-1.5wt%Mg-0.2wt%Zn-0.2wt%Si nanoparticles (NPs), which were functionalized using collagen type 1 molecules (COL), resulting in ms-HAP/COL (core/shell) NPs that were embedded into a polylactic acid (PLA) matrix and finally covered with COL layers, obtaining the ms-HAP/COL@PLA/COL composite. To assess the osseointegration issue, first, the thickness, surface morphology and roughness of the BC coating on the Ti implants were determined using AFM and SEM. The BC-coated Ti implants and uncoated Ti implants were then used in Wistar albino rats with a diaphyseal femoral fracture, both in the absence and the presence of high-frequency pulsed electromagnetic shortwave (HF-PESW) stimulation. This study was performed using a bone marker serum concentration and histological and computer tomography (micro-CT) analysis at 2 and 8 weeks after surgical implantation. The implant osseointegration was evaluated through the bone–implant contact (BIC). The bone–implant interface was investigated using FE-SEM images and EDX spectra of the retrieved surgical implants at 8 weeks in the four animal groups. The obtained results showed significantly higher bone–implants contact and bone volume per tissue volume, as well as a greater amount of newly formed bone, in the BC-coated Ti implants than in the uncoated Ti implants. Direct bone–implant contact was also confirmed via histological examination. The results of this study confirmed that these biomimetic composite coatings on Ti implants were essential for a significant enhancement of osseointegration of BC-coated Ti implants and bone regeneration. This research provides a novel strategy for the treatment of bone fractures with possible orthopedic applications.

scholarly journals An Atraumatic Femoral Fracture in a Patient with Rheumatoid Arthritis and Osteoporosis Treated with Denosumab

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
J. Villiers ◽  
D. W. Clark ◽  
T. Jeswani ◽  
S. Webster ◽  
A. L. Hepburn
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Monoclonal Antibody ◽  
Femoral Fracture ◽  
Mineral Density ◽  
Mineral Supplementation ◽  
Antiresorptive Agents ◽  
Significant Burden ◽  
Diaphyseal Femoral Fracture

Osteoporosis is responsible for a significant burden both individually and socially, but is readily treated with antiresorptive agents and mineral supplementation. However, long-term usage of these agents, notably bisphosphonates, is rarely associated with atypical fractures. Denosumab is a monoclonal antibody that reduces osteoclast activity and thus increases bone mineral density. In this case report, we present a 78-year-old woman with a background of rheumatoid arthritis and osteoporosis who presented with an atypical diaphyseal femoral fracture.

Interlocking Intramedullary Nail Fixation for a Comminuted Diaphyseal Femoral Fracture in an Alpaca

1999 ◽  
Vol 12 (02) ◽  
pp. 81-84 ◽  
Author(s):  
J. K. Roush ◽  
R. M. DeBowes ◽  
J. Mills ◽  
J. D. Lillich
Keyword(s):  
Intramedullary Nail ◽  
Bone Fracture ◽  
Femoral Fracture ◽  
New World ◽  
Small Ruminants ◽  
Fracture Repair ◽  
Long Bone ◽  
Long Bone Fracture ◽  
Interlocking Intramedullary Nail ◽  
Diaphyseal Femoral Fracture

While reports of long bone fracture repair in new world camelids are limited, clinical cases are more frequently encountered. Options from repair have been similar to those chosen for small ruminants. The use of an interlocking intramedullary nail for a comminuted mid-diaphyseal femoral fracture proved to be successful. Based on the relatively straight and narrow shape of the femur of new world camelids and the results of this case, the interlocking intramedullary nail may be a suitable option for long bone fracture repair in these species.

Remodeling of angulation deformities in diaphyseal femoral fracture in children

2012 ◽  
Vol 17 (6) ◽  
pp. 763-769 ◽  
Author(s):  
Makoto Kamegaya ◽  
Takashi Saisu ◽  
Yuko Segawa ◽  
Jun Kakizaki ◽  
Yuko Sakamoto ◽  
...  
Keyword(s):  
Femoral Fracture ◽  
Diaphyseal Femoral Fracture
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