scholarly journals Possibilities of CT perfusion in diagnostics of periampullary tumors

2021 ◽  
Vol 12 (1) ◽  
pp. 80-86
Author(s):  
T. N. Trofimova ◽  
M. Ya. Belikova ◽  
D. M. Yakovleva ◽  
M. M. Druzina

Purpose. To study the possibilities of CT perfusion (CTP) in detecting periampullary tumors depending on the anatomical localization, to compare the diagnostic efficiency with the standard CT protocol. Materials and methods. CT scan of the abdominal organs according to the standard protocol and CTP were performed in 229 patients with periampullary tumors. Results. In adenocarcinoma of the pancreas, compared with adenocarcinoma of the major duodenal papilla, BF, BV, MSI (p<0,005) were statistically significantly lower, there were no differences in MTT, TTP, and PS (p>0,005). In distal cholangiocarcinoma, compared with adenocarcinomas of the pancreas and the major duodenal papilla (MDP), the BF, BV and MSI values were statistically significantly higher, the TTP values were lower (p<0,005), there were no differences in the MTT and PS values (p>0,005). Conclusion. CT perfusion is a highly informative method for detecting and determining the anatomical affiliation of periampullary tumors with a sensitivity of 98,7%, a specificity of 98%, and a diagnostic accuracy of 98,4%.

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1121
Author(s):  
Georgios S. Ioannidis ◽  
Søren Christensen ◽  
Katerina Nikiforaki ◽  
Eleftherios Trivizakis ◽  
Kostas Perisinakis ◽  
...  

The aim of this study was to define lower dose parameters (tube load and temporal sampling) for CT perfusion that still preserve the diagnostic efficiency of the derived parametric maps. Ninety stroke CT examinations from four clinical sites with 1 s temporal sampling and a range of tube loads (mAs) (100–180) were studied. Realistic CT noise was retrospectively added to simulate a CT perfusion protocol, with a maximum reduction of 40% tube load (mAs) combined with increased sampling intervals (up to 3 s). Perfusion maps from the original and simulated protocols were compared by: (a) similarity using a voxel-wise Pearson’s correlation coefficient r with in-house software; (b) volumetric analysis of the infarcted and hypoperfused volumes using commercial software. Pearson’s r values varied for the different perfusion metrics from 0.1 to 0.85. The mean slope of increase and cerebral blood volume present the highest r values, remaining consistently above 0.7 for all protocol versions with 2 s sampling interval. Reduction of the sampling rate from 2 s to 1 s had only modest impacts on a TMAX volume of 0.4 mL (IQR −1–3) (p = 0.04) and core volume of −1.1 mL (IQR −4–0) (p < 0.001), indicating dose savings of 50%, with no practical loss of diagnostic accuracy. The lowest possible dose protocol was 2 s temporal sampling and a tube load of 100 mAs.


2010 ◽  
Vol 21 (2) ◽  
pp. S87-S88
Author(s):  
L.N. Boucher ◽  
C. Dey ◽  
R. Gadahadh ◽  
T. Cabrera ◽  
N. Khattar ◽  
...  

2010 ◽  
Vol 43 (11) ◽  
pp. 1129-1133
Author(s):  
Yasunori Kurahashi ◽  
Yoshiharu Shirakata ◽  
Koji Hirata ◽  
Hisashi Shinohara ◽  
Kazumi Itoi ◽  
...  

2021 ◽  
pp. 31-35
Author(s):  
O. V. Gorbulitch ◽  
S. H. Yefimenko ◽  
S. A. Pavlychenko ◽  
O. A. Lazutkina ◽  
K. A. Aleksanian

Postcholecystectomy syndrome is a symptom complex that occurs or worsens after cholecystectomy and is a functional and / or organic disorder. It often complicates the post−surgery course of gallstone disease. The presence of symptoms of the disease indicates a deterioration in the quality of life of patients, but the diagnostic examination is not always possible to detect morphological or functional changes. Thus, at present the syndrome is an urgent problem of gastroenterology and biliary surgery. Diagnostic issues with a differentiated approach to the functional or organic nature of postcholecystectomy syndrome are important for the choice of further treatment tactics. In order to improve the diagnostic algorithm taking into account the changes in the area of the major duodenal papilla, a study was conducted in 137 patients. To determine the functional disorders of the sphincter of Oddi there was used the method of ultrasound investigation of hepatobiliary area and Vater's papilla with choleretic loading on Boyden as well as the Grigoriev's methods in the absence of organic obstruction of the terminal choledochus at previous stages of examination. Morphological changes in the major duodenal papilla area were evaluated using the technique of parietal ph−impedancemetry, which was performed on the background of benign mechanical jaundice in the patients after cholecystectomy during endoscopic retrograde cholangiopancreatography prior to endoscopic papillosphincterotomy. The obtained results help to perform a differentiated approach to the patients who underwent cholecystectomy, taking into account morphofunctional changes in the area of the major duodenal papilla and allow the implementation of the selected methods to the research algorithm of patients with postcholecystectomy syndrome. Key words: postcholecystectomy syndrome, functional and organic changes of major duodenal papilla, patency of the terminal choledochus, treatment tactics.


2020 ◽  
Vol 92 (1) ◽  
pp. 227-229 ◽  
Author(s):  
Amil Sinha ◽  
Dylan Thiarya ◽  
Shaan Patel ◽  
Mythiri Sutharson ◽  
Cecilia Brassett ◽  
...  

2015 ◽  
Vol 12 (1) ◽  
pp. 22-24 ◽  
Author(s):  
Sharmina Sayeed ◽  
Shamim Ara ◽  
Mesbahul Hoque ◽  
Zannatul Ferdous ◽  
Kanetarin Kashem

Context: The major duodenal papilla is one of the most fascinating papilla present at the duodenum attracting many gastroenterologists as they do endoscopic retrograde cholangiopancreatiography (ERCP) for diagnosis and treatment purpose of many diseases. Most of the textbooks of Anatomy describe that the summit of major duodenal papilla is situated posteromedially in the descending part of duodenum. Henceforth the present study was undertaken in 70 human duodenums to observe the location of major duodenal papilla. Materials & Methods: A cross-sectional observational study was conducted in the department of Anatomy, Dhaka Medical College, Dhaka from July 2010 to June 2011. Seventy postmortem human duodenums were collected from unclaimed dead bodies that were under examination in the morgue of department of Forensic Medicine and the department of Anatomy of Dhaka Medical College, Dhaka. Location of major duodenal papilla was observed and recorded. Results: The location of major duodenal papilla was observed in the medial wall of second part of duodenum in 78.6% specimens, in the posteromedial wall of second part in 15.7% cases and in the posteromedial wall of the junction between second and third part in 4.3% and absent in 1.4% duodenum. Conclusion: The location of major duodenal papilla varies in position. DOI: http://dx.doi.org/10.3329/bja.v12i1.22614 Bangladesh Journal of Anatomy, January 2014, Vol. 12 No. 1 pp 22-24


2001 ◽  
Vol 53 (1) ◽  
pp. 121-123 ◽  
Author(s):  
Chien-Hua Chen ◽  
Chi-Chieh Yang ◽  
Yung-Hsiang Yeh ◽  
Der-Aur Chou ◽  
Chien-Long Kuo

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