Clinical features, management and visual outcomes on patients with traumatic hyphema in a reference  ophthalmological clinic in Colombia

PurposeTo describe the clinical features, treatment and visual outcomes of Japanese patients with new-onset acute Vogt-Koyanagi-Harada (VKH) disease.MethodsClinical records of 111 patients who presented between 1999 and 2015 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo, were reviewed.ResultsOf the 111 patients (68 women, 43 men), 16 had complete, 90 had incomplete and 5 had probable VKH disease. The median follow-up period was 36 months (4–175 months). The mean age at presentation was 41 years (19–74 years). Serous retinal detachment (202 eyes) and optic disc hyperaemia (89 eyes) were observed at presentation. Of the patients tested, 45/48 (93.8%) were human leucocyte antigen-DR4 positive and 63/77 (81.8%) had cerebrospinal fluid pleocytosis. Initial corticosteroid treatment consisted of pulse intravenous therapy in all patients. Sunset glow fundus was observed in 49.5% of eyes, and anterior and/or posterior segment recurrence of inflammation was observed in 25 patients (22.5%). Treatment was transitioned to cyclosporine in 17 patients (15.3%) for steroid sparing (6 patients) or recurrent inflammation (11 patients), with good subsequent control. Ocular complications were observed in 47 of 222 eyes (21.2%) (mostly cataract), and systemic complications were observed in 8.1% of patients (mostly hypertension and diabetes mellitus). Ninety-three percent of eyes (167 of 178 eyes) had a visual acuity of ≥1.0 at 1 year after presentation.ConclusionsAn aggressive corticosteroid treatment strategy in a large number of patients with new-onset acute VKH disease, with transitioning to cyclosporine in selected cases, resulted in excellent visual outcomes and low rates of recurrence.

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Clinical features and visual outcomes of Japanese patients with scleritis

British Journal of Ophthalmology ◽

10.1136/bjo.2009.171744 ◽

2010 ◽

Vol 94 (11) ◽

pp. 1459-1463 ◽

Cited By ~ 28

Author(s):

H. Keino ◽

T. Watanabe ◽

W. Taki ◽

C. Nakashima ◽

A. A. Okada

Keyword(s):

Clinical Features ◽

Japanese Patients ◽

Visual Outcomes

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Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes

Eye ◽

10.1038/s41433-021-01449-6 ◽

2021 ◽

Author(s):

Yao Yang ◽

Wenjun Sui ◽

Fang Duan ◽

Yujie Li ◽

Jieting Zeng ◽

...

Keyword(s):

Preschool Children ◽

Clinical Features ◽

Silicone Oil ◽

Age Groups ◽

Common Cause ◽

Visual Outcomes ◽

Antibiotic Susceptibilities ◽

Post Traumatic ◽

Silicone Oil Tamponade ◽

Viridans Group Streptococci

Abstract Background/Objectives Streptococcus is a common cause of post-traumatic endophthalmitis in children. This study aimed to analyse the clinical features, antibiotic susceptibilities and outcomes of traumatic endophthalmitis caused by streptococcus in preschool children. Subjects/Methods Patients aged ≤6 years with traumatic streptococcal endophthalmitis seen at Zhongshan Ophthalmic Center between January 2013 and December 2018 were included in this retrospective study. Results In total, 21 patients (21 eyes) were included. The mean age of the patients was 3.3 ± 1.7 years, where 57.1% were males. Scissors (28.6%, n = 6) were the most common cause of injury; 86.7% of patients were injured at home. Zone I (80.9%) was the most common wound site; 90.5% of patients presented with a traumatic cataract. In general, Streptococcus pneumoniae (47.6%) was the most common isolate. Viridans group streptococci accounted for 58.3% of cases in children aged 0–3 years, while S. pneumoniae accounted for 66.7% of cases in children aged 4–6 years. The susceptibility rates of streptococcus to cefuroxime, levofloxacin and ofloxacin were 100%, 95.0% and 90.5%, respectively. Although all the patients underwent vitrectomy combined with silicone oil tamponade, the final visual outcomes were no better than counting fingers. Conclusions Although S. pneumoniae was the most prevalent organism in general, the dominant species varied between different age groups. The commonly used antibiotics, cefuroxime and fluoroquinolone, showed higher antibiotic susceptibility. Despite prompt treatment, the visual outcomes of paediatric post-traumatic endophthalmitis in preschool children were poor.

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Clinical features, anatomical and visual outcomes, and prognostic factors in closed globe injuries presenting with no light perception: Eye Injury Vitrectomy Study

Acta Ophthalmologica ◽

10.1111/j.1755-3768.2011.02325.x ◽

2011 ◽

Vol 90 (6) ◽

pp. e493-e494 ◽

Cited By ~ 2

Author(s):

Kang Feng ◽

Zhi-zhong Ma

Keyword(s):

Prognostic Factors ◽

Clinical Features ◽

Eye Injury ◽

Light Perception ◽

Visual Outcomes

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LONG-TERM VISUAL OUTCOMES AND CLINICAL FEATURES AFTER ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION–RELATED ENDOPHTHALMITIS

Retina ◽

10.1097/iae.0000000000002300 ◽

2019 ◽

Vol 39 (11) ◽

pp. 2070-2076 ◽

Cited By ~ 3

Author(s):

Nadim Rayess ◽

Anthony Obeid ◽

Philip P. Storey ◽

Joseph Juliano ◽

Ehsan Rahimy ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Clinical Features ◽

Vascular Endothelial ◽

Visual Outcomes ◽

Endothelial Growth Factor

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Endophthalmitis following Intravitreal Injection, Cataract Surgery, and Vitrectomy: Clinical Features and Visual Outcomes

Journal of Ophthalmology ◽

10.1155/2021/9985821 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Ana Maria Cunha ◽

Maria Manuel Iglésias ◽

Amândio Rocha-Sousa ◽

Fernando Falcão-Reis ◽

Manuel Falcão

Keyword(s):

Cataract Surgery ◽

Clinical Features ◽

Primary Outcome ◽

Visual Outcome ◽

Single Centre ◽

Visual Outcomes ◽

Poor Visual Outcome ◽

Number Of Patients ◽

Pars Plana ◽

Better Than

Purpose. To describe and compare the clinical features and visual outcomes of endophthalmitis following intravitreal injections (IVI), cataract surgery, and pars plana vitrectomy (PPV). Methods. This is a single-centre, retrospective study. All included patients had acute postoperative endophthalmitis secondary to one of these three procedures. Visual acuity (VA), comorbidities, time to presentation, and treatment were assessed. The primary outcome was visual outcome. A poor outcome was considered if final VA was worse than or equal to counting fingers (CF) and a good outcome was classified as VA better than CF. Results. Over 12 years, a total of 61 patients were included. Twenty-seven cases were post-cataract endophthalmitis; twenty-five were post-IVI and nine post-PPV. Endophthalmitis post-PPV had a worse visual outcome (88.9% of patients with VA worse than or equal to CF 95% CI 51.3 to 100.0%) than endophthalmitis following cataract surgery (25.9% of patients with VA worse than or equal to CF 95% CI 11.0 to 39.9%) and the IVI subgroup (44.0% of VA worse than or equal to CF 95% CI 24.0 to 67.0%) ( p = 0.001 and p = 0.047 ). There were no significant differences in the proportion of patients with a poor visual outcome between endophthalmitis following cataract surgery and IVI ( p = 0.171 ). Conclusions. The number of patients with poor visual outcomes following acute endophthalmitis was similar in endophthalmitis following IVI and cataract surgery, but better than endophthalmitis following vitrectomy.

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