scholarly journals Accuracy of antepartum ultrasound in evaluating placental pathology using superb microvascular imaging: main research article

Author(s):  
Natsumi Furuya ◽  
JUNICHI HASEGAWA ◽  
Masatomo Doi ◽  
Junki Koike ◽  
Nao Suzuki

Objectives: To clarify whether microvascular ultrasound Doppler (SMI: superb microvascular imaging) can detect antenatal histological findings in pathologic placentas. Methods: In this prospective diagnostic observational study (STROBE), pregnant women who were admitted to our perinatal center for perinatal management were enrolled. Ultrasound examinations to identify placental pathologies using SMI were performed before delivery. After delivery, the placental tissue was clipped for microscopic examination, as the location of the placenta obtained ultrasound findings. The accuracy of antenatal ultrasound detection of placental pathologies was compared between women who were admitted due to fetal growth restriction (FGR), pre-eclampsia, and other indications. Results: The highest accuracy was observed with placental infarction in FGR (positive predictive value [PPV], 100%; sensitivity, 89%; area under the curve [AUC], 0.945), whereas PPV, sensitivity, and AUC in cases of preeclampsia were relatively low (AUC 0.540). Additionally, PPV, sensitivity, and AUC for avascular villi were 100%, 57%, and 0.785 in cases with FGR, 67%, 67%, and 0.780 in cases with preeclampsia, and 80%, 80%, and 0.920, respectively. The diagnostic accuracies predictive of congestion of stem villi and chorangiosis were insufficient (AUC<0.700). Conclusions: SMI can accurately detect placental pathologic findings, such as placental infarction and avascular villi. This modality may improve the perinatal management in cases of placental abnormalities.

Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 652
Author(s):  
Giulio Cocco ◽  
Andrea Delli Pizzi ◽  
Stefano Fabiani ◽  
Nino Cocco ◽  
Andrea Boccatonda ◽  
...  

Background: Post-anti-COVID-19 vaccine lymphadenopathy has recently been described in the literature. In this study, we investigated the multiparametric US findings of patients with post-vaccine lymphadenopathy and compared these findings among different anti-COVID-19 vaccines. Methods: We retrospectively evaluated 24 patients who underwent US between January and May 2021 due to post-anti-COVID-19 lymphadenopathy. The presence, size, location, number, morphology, cortex-hilum, superb microvascular imaging (SMI) and elastosonography of lymph nodes were assessed. Descriptive statistics were calculated and differences among anti-COVID-19 vaccines were analyzed using the Kruskal–Wallis test. A p-value ≤ 0.05 was considered statistically significant. Results: Sixty-six nodes were assessed. They were axillary (mean 1.6 cm ± 0.16) in 11 patients (45.8%) and supraclavicular (mean 0.9 cm ± 0.19) in 13 patients (54.2%). In 20 patients (83.3%), the number of nodes was ≤3. Prevalent US features included oval morphology (18, 75%), asymmetric cortex with hilum evidence (9, 37.5%), central and peripheral vascular signals (12, 50%) at SMI and elastosonography patterns similar to the surrounding tissue (15, 71.4%). No significant differences among the three anti-COVID-19 vaccines were observed (p > 0.05). Conclusions: Anti-COVID-19 vaccines may present lymphadenopathy with “worrisome” US features regarding size, shape, morphology, cortex-hilum, SMI and elastosonography. An awareness of the patient’s history and US findings may help in the early recognition of this clinical scenario and in the appropriate selection of patients for a short-term US follow-up.


2020 ◽  
Vol 20 (82) ◽  
pp. 185-190
Author(s):  
Hakan Cebeci ◽  
◽  
Mehmet Öztürk ◽  
Mehmet Sedat Durmaz ◽  
Abidin Kılınçer ◽  
...  

Aim of the study: This study aimed to examine the role of superb microvascular imaging and shear wave elastography for the pre-surgical evaluation of common parotid tumors. Material and methods: This single-center prospective study included 37 patients with parotid gland lesions. After institutional review board approval, grayscale, shear wave elastography and superb microvascular imaging ultrasound examinations were performed prior to biopsy or operation. The diagnosis of the lesions was based on cytological/pathological evaluation after the ultrasound examinations. Pleomorphic adenomas and Warthin tumors were compared using the Mann–Whitney U test. A receiver operating characteristic curve analysis was performed to obtain a cut-off value. A multivariate regression analysis was carried out. Results: The mean age of the patients (11 female, 26 male) was 48.2 ± 18. The shear wave elastography parameters of the lesions were not significantly different between pleomorphic adenomas and Warthin tumors, while the vascular index obtained by using superb microvascular imaging was significantly different (p = 0.012). The mean vascular index was 2.9 ± 3.1 in pleomorphic adenomas, and 9.5 ± 9.5 in Warthin tumors. A cut-off value of 4.05 for the vascular index discriminated pleomorphic adenoma and Warthin tumors with 68% sensitivity and 72% specificity (the area under the curve was 0.768). Conclusion: Superb microvascular imaging is a novel ultrasound imaging technique which is useful for the discrimination of pleomorphic adenomas and Warthin tumors.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Lihui Zhao ◽  
Yiran Mao ◽  
Jie Mu ◽  
Jing Zhao ◽  
Fangxuan Li ◽  
...  

Abstract Background We compared the ultrasound features, superb microvascular imaging (SMI) and micro vessel density (MVD) of pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) to explore the clinic value of SMI in differential diagnosis of benign tumors of parotid gland. Methods The vascular distributions and grade by color doppler flow imaging (CDFI) and SMI, as well as vascular index (VI) of 249 parotid gland masses from 217 patients were analyzed. Results The internal echogenicity of BCA are more homogeneous in comparing with WT and PA(P < 0.05). By SMI, the vascular distribution and vascular grade in PA were mainly peripheral (33.1%) and avascular (25.7%), Grade 1 (27.8%) and Grade 0 (25.7%). WT were mainly central (31.3%) and mixed distribution (34.9%), in Grade 3 (37.3%) and Grade 2 (36.2%). BCA was mainly peripheral (33.3%) and mixed distribution (33.3%), in Grade 2 (33.3%) and Grade 3 (33.3%). The overall detection rate of SMI for vascular Grade 2 and 3 was significantly higher than that of CDFI (P < 0.05). Both VI and MVD were lowest in PA, highest in WT (P < 0.001). The VI by SMI was correlated with MVD (P < 0.001). The correlation index between vascular distribution and grade by SMI and MVD were significantly higher than CDFI. Conclusion SMI can provide low-velocity blood flow information, which is helpful for the differential diagnosis of common benign tumors of parotid gland, and is expected to be more widely used.


2019 ◽  
Vol 38 (9) ◽  
pp. 2485-2491 ◽  
Author(s):  
Lauren M. Mack ◽  
Joan M. Mastrobattista ◽  
Rajshi Gandhi ◽  
Eumenia C. Castro ◽  
Angela P.H. Burgess ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document