The protective effect of vitamin E against genotoxicity of lead acetate intraperitoneal administration in male rat

This is a notice of retraction of the article: The protective effect of vitamin E against genotoxicity of lead acetate intraperitoneal administration in male rat, published in the Archives of Biological Sciences in 2013, Vol. 65, Issue 4. The Editor-in-Chief has been informed that this paper is a duplicate of an earlier paper: Hamadouche NA, Sadi N, Kharoubi O, Slimani M, Aoues A. The protective effect of vitamin E against genotoxicity of lead acetate intraperitoneal administration in male rat. Notulae scientia biologicae. 2013;5(4):412-9. This claim is correct and the results have already been presented in the article published earlier. After confirmation of this fact, the Editor-in-Chief of the Archives of Biological Sciences has decided to retract the paper immediately. We apologize for this error. Link to the retracted article <a href="http://dx.doi.org/10.2298/ABS1304435H">10.2298/ABS1304435H</a>

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The Protective Effect of Vitamin E Against Genotoxicity of Lead Acetate Intraperitoneal Administration in Male Rat

Notulae Scientia Biologicae ◽

10.15835/nsb549125 ◽

2013 ◽

Vol 5 (4) ◽

pp. 412-419 ◽

Cited By ~ 3

Author(s):

Nadia AITHAMADOUCHE ◽

Nesrine SADI ◽

Omar KHAROUBI ◽

Miloud SLIMANI ◽

Abdelkader AOUES

Keyword(s):

Vitamin E ◽

Lead Acetate ◽

Sperm Morphology ◽

Intraperitoneal Administration ◽

Male Rat ◽

Protective Effects ◽

Sperm Counts ◽

Male Wistar Rats ◽

E 600 ◽

Sexually Mature

Lead is industrial pollutant that may have toxic effects on the male. The aim of this study was to further investigate the protective effects of vitamin E on lead acetate (Pb) induced reproductive toxicities and genotoxicity effects in male rat. Sexually mature male Wistar rats (weighing 120-160 g) were given Pb (20 mg/Kg) and vitamin E (600 mg/kg/rat) orally for 20 days. The sperm counts, sperm motility, sperm morphology, chromosomal aberrations, FSH, LH and testosterone levels, and histopathological changes in the testes of these rats, were investigated at the end of 20 days. Result revealed a statistically significant (p

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Protective effect of hydroalcoholic Rheum ribes L. extract in male rat model of lead acetate-induced nephrotoxicity

Journal of Nephropathology ◽

10.15171/jnp.2018.20 ◽

2017 ◽

Vol 7 (2) ◽

pp. 83-87

Author(s):

Shirin Asgharian ◽

Hasan Hoseinkhani ◽

Elham Bijad ◽

Zahra Lorigooini ◽

Mahmoud Rafieian-Kopaei

Keyword(s):

Protective Effect ◽

Rat Model ◽

Lead Acetate ◽

Male Rat

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The Protective Effect of Melatonin vs. Vitamin E in the Ischemic/Reperfused Skeletal Muscle in the Adult Male Rat Model

Journal of Cytology & Histology ◽

10.4172/2157-7099.s3-005 ◽

2015 ◽

Vol s3 ◽

Author(s):

Enas A Mohamed

Keyword(s):

Skeletal Muscle ◽

Vitamin E ◽

Protective Effect ◽

Adult Male ◽

Rat Model ◽

Male Rat ◽

Adult Male Rat

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Protective Effect of Vitamin E Against Ethanol-Induced Hyperhomocysteinemia, DNA Damage, and Atrophy in the Developing Male Rat Brain

Alcoholism Clinical and Experimental Research ◽

10.1111/j.1530-0277.2009.00941.x ◽

2009 ◽

Vol 33 (7) ◽

pp. 1181-1186 ◽

Cited By ~ 42

Author(s):

Alireza Shirpoor ◽

Siamak Salami ◽

Mohammad Hassan Khadem-Ansari ◽

Syranush Minassian ◽

Marine Yegiazarian

Keyword(s):

Dna Damage ◽

Vitamin E ◽

Protective Effect ◽

Rat Brain ◽

Male Rat

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Protective Effect of Vitamin E on Immune Triggered, Granulocyte Mediated Endothelial Injury

Thrombosis and Haemostasis ◽

10.1055/s-0038-1661027 ◽

1984 ◽

Vol 51 (01) ◽

pp. 089-092 ◽

Cited By ~ 24

Author(s):

M A Boogaerts ◽

J Van de Broeck ◽

H Deckmyn ◽

C Roelant ◽

J Vermylen ◽

...

Keyword(s):

Vitamin E ◽

Protective Effect ◽

Umbilical Vein ◽

Endothelial Damage ◽

Endothelial Injury ◽

Mediated Effects ◽

Anti Oxidant ◽

Endothelial Cell Cultures ◽

Vitro Model

SummaryThe effect of alfa-tocopherol on the cell-cell interactions at the vessel wall were studied, using an in vitro model of human umbilical vein endothelial cell cultures (HUEC). Immune triggered granulocytes (PMN) will adhere to and damage HUEC and platelets enhance this PMN mediated endothelial injury. When HUEC are cultured in the presence of vitamin E, 51Cr-leakage induced by complement stimulated PMN is significantly decreased and the enhanced cytotoxicity by platelets is completely abolished (p <0.001).The inhibition of PMN induced endothelial injury is directly correlated to a diminished adherence of PMN to vitamin E- cultured HUEC (p <0.001), which may be mediated by an increase of both basal and stimulated endogenous prostacyclin (PGI2) from alfa-tocopherol-treated HUEC (p <0.025). The vitamin E-effect is abolished by incubation of HUEC with the irreversible cyclo-oxygenase inhibitor, acetylsalicylic acid, but the addition of exogenous PGI2 could not reproduce the vitamin E-mediated effects.We conclude that vitamin E exerts a protective effect on immune triggered endothelial damage, partly by increasing the endogenous anti-oxidant potential, partly by modulating intrinsic endothelial prostaglandin production. The failure to reproduce vitamin E-protection by exogenously added PGI2 may suggest additional, not yet elucidated vitamin E-effects on endothelial metabolism.

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