scholarly journals Results of supraglottic partial horizontal laryngectomies

2003 ◽  
Vol 56 (11-12) ◽  
pp. 568-570
Author(s):  
Zeljko Petrovic
Keyword(s):  
Neck Dissection ◽  
Postoperative Radiotherapy ◽  
Radical Neck Dissection ◽  
Disease Free Survival ◽  
Functional Results ◽  
Selective Neck Dissection ◽  
Simultaneous Treatment ◽  
Supraglottic Laryngectomy ◽  
Laryngeal Surgery ◽  
Primary Surgery

Introduction Supraglottis is a part of larynx comprising two sub regions: epilarynx (suprahyoid epiglottis - including lingual and laryngeal surface, aryepiglottic folds - laryngeal surface, and arytenoids) and supraglottis without epilarynx (infrahyioid epiglottis and ventricular folds). Material and methods A total of 234 patients with supraglottic squamous cell carcinoma undergoing primary surgery were analyzed in the period 1976-1996. The tumor was localized in epilarynx in 84 (25%) patients, and in supraglottis without epilarynx in 261 (75%) cases. Results T1 tumor was present in 145 (42%) patients, T2 tumor was found in 178 (52%) patients, while T3 was reported in 22 (6%) cases. Clinically negative neck (N0) was found in 290 (84%) patients, and palpable metastases (N1) manifested in 55 (16%) cases. Local recurrences were established in 18 (5%) patients, and subsequent postoperative cervical metastases were found in 45 (13%) cases. Five-year disease-free survival was reported in all patients approximately 12 days following surgery. 27 patients developed laryngeal stenosis and only 2 patients were not decanulated. Voice and speech functions were satisfactory. Discussion Supraglottic laryngectomy, extended supraglottic laryngectomy is fully justified from oncological and functional aspects. Selective neck dissection in N0 cervical findings provides detection of occult metastases and indicates need for postoperative radiotherapy. Conclusion Oncological and functional results of supraglottic laryngeal surgery, along with simultaneous treatment of neck by selective, modified radical neck dissection and postoperative radiotherapy offer hope for treatment of supraglottic laryngeal cancer.

scholarly journals Surgical treatment of the supraglottic laryngeal carcinoma

2008 ◽  
Vol 61 (5-6) ◽  
pp. 242-246 ◽  
Author(s):  
Zeljko Petrovic ◽  
Vladimir Djordjevic ◽  
Vladimir Nesic
Keyword(s):  
Survival Rate ◽  
Neck Dissection ◽  
Retrospective Analysis ◽  
Radical Neck Dissection ◽  
Disease Free Survival ◽  
Functional Results ◽  
Selective Neck Dissection ◽  
Tumor Spread ◽  
Negative Finding ◽  
Disease Free Survival Rate

This is a retrospective analysis of 439 patients with supraglottic laryngeal cancer primary surgically treated in the period 1976-1999. The objectives of our study were to analyze the localizations as well as local and regional tumor spread, frequency of occult and palpable cervical metastases, the incidence of local and regional recurrences, five-year survival rate and functional results of supraglottic partial horizontal laryngectomies. A retrospective analysis of operated patients was carried out. T1 tumor was prevalent in 184 (42%) patients, T2 in 228 (52%) patients, and T3 tumor in 27 (6%) of cases. Clinically negative finding of the neck was found in 369 (84%) patients, and metastasis N1 was established in 70 (16%) patients. The patients with clinically negative cervical finding underwent selective neck dissection, while N1 metastasis patients were subjected to a selective or modified radical neck dissection. Five-year disease-free survival rate was 76% (334/439).

S174 – Therapeutic Selective Neck Dissection Outcomes

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P134-P134
Author(s):  
Peter M Shepard ◽  
Olson Jordan ◽  
Glen E Leverson ◽  
Paul M Harari ◽  
Gregory K Hartig
Keyword(s):  
Neck Dissection ◽  
Primary Tumor ◽  
Postoperative Radiotherapy ◽  
Radical Neck Dissection ◽  
Retrospective Chart Review ◽  
Regional Recurrence ◽  
Selective Neck Dissection ◽  
Nodal Metastases ◽  
Neck Node ◽  
Primary Tumor Site

Objectives To examine the efficacy of selective neck dissection in patients with nodal metastases from head and neck squamous cell carcinoma. Methods A retrospective chart review was performed on a cohort of 156 subjects with clinically positive regional nodal metastases, whose initial management included neck dissection by a single surgeon from 1994–2007. 69 subjects underwent selective neck dissection (SND), while 87 underwent radical or modified radical neck dissection (R/MRND). The majority of subjects (81%) received postoperative radiotherapy. Primary outcomes included 3-year regional recurrence and 5-year overall survival, using Kaplan-Meier analysis. Results Following exclusion of subjects with local recurrence before or concurrent with regional recurrence, there were 4 (8.6%) regional recurrences in the SND group and 15 (22%) in the R/MRND group. 2 and 6 of these recurrences involved the contralateral neck in each group, respectively. Using multivariate analysis we adjusted for differences in nodal and primary tumor stage, primary tumor site, year of surgery, extracapsular spread, and postoperative radiotherapy rates. The lower regional recurrence rate in the SND group remained statistically significant (p=0.02). Overall 5-year survival was 46% in the SND group vs. 34% in the R/MRND group (p=0.23). Conclusions These results demonstrate excellent regional disease control following SND in patients with neck node metastases. SND with adjunctive radiotherapy remains our preferred approach for most patients undergoing therapeutic neck dissection.

In patients with metastatic cutaneous head and neck squamous cell carcinoma to cervical lymph nodes, the extent of neck dissection does not influence outcome

2012 ◽  
Vol 127 (S1) ◽  
pp. S2-S7 ◽  
Author(s):  
J T Wang ◽  
C E Palme ◽  
A Y Wang ◽  
G J Morgan ◽  
V Gebski ◽  
...  
Keyword(s):  
Overall Survival ◽  
Neck Dissection ◽  
Adjuvant Radiotherapy ◽  
Radical Neck Dissection ◽  
Disease Free Survival ◽  
Selective Neck Dissection ◽  
Cervical Lymph Nodes ◽  
Free Survival ◽  
Modified Radical Neck Dissection ◽  
Disease Free

AbstractBackground:This study aimed to compare recurrence and survival in patients undergoing either selective neck dissection or modified radical neck dissection to treat metastatic cutaneous head and neck squamous cell carcinoma to the cervical lymph nodes (levels I–V) only.Methods:Twenty-eight year, retrospective analysis of a prospectively maintained database from a tertiary referral hospital, with a minimum follow up of two years.Results:There were 122 eligible patients: 96 males (79 per cent) and 26 (21 per cent) females (median age, 66 years). Sixty-six patients (54 per cent) underwent selective neck dissection and 56 (46 per cent) modified radical neck dissection. The former patients had a lower rate of regional recurrence compared with the latter (17 vs 23 per cent, respectively). There was no significant difference in five-year overall survival (61 vs 57 per cent, respectively) or five-year disease-free survival (74 vs 60 per cent, respectively), comparing the two groups. Overall survival and disease-free survival were significantly improved by the addition of adjuvant radiotherapy.Conclusion:We found no difference in outcome in patients undergoing selective versus modified radical neck dissection. Adjuvant radiotherapy significantly improved outcome.

scholarly journals Treatment of metastatic neck squamous cell carcinomas with unknown primary

2004 ◽  
Vol 57 (3-4) ◽  
pp. 168-170
Author(s):  
Zeljko Petrovic ◽  
Svetislav Jelic
Keyword(s):  
Lymph Nodes ◽  
Head And Neck ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Postoperative Radiotherapy ◽  
Radical Neck Dissection ◽  
Disease Free Survival ◽  
Palliative Radiotherapy ◽  
Squamous Cell Carcinomas ◽  
Unknown Primary

Introduction Treatment of metastatic neck squamous cell carcinomas of unknown primary is one of the most serious problems in head and neck oncology. Material and methods Fifty-one patients were analyzed during the period 1977-1997. All patients underwent clinical examination of head and neck, hematological and laboratory tests, X-ray of paranasal sinuses, esophagus and lungs, scintigraphy of the thyroid gland, epipharyngoscopy, esophagoscopy and laryngotracheobronchoscopy, biopsy of suspected changes and blind biopsy of suspected regions (epipharynx, tongue base, piriform sinus), ipsilateral tonsillectomy (17 patients), examination of gastrointestinal tract, kidneys, prostate, testicles, and breasts and ovaries, respecti- vely. Results Almost half of metastases developed in the II level of the neck (49.01%; 25/51). Most metastases were 3-6cm in diameter (N2) - 60.76% (31/51). Forty patients were surgically treated by various neck dissection methods and postoperative radiotherapy (60 Gy). Palliative radiotherapy was applied in patients with inoperable metastases. Eighteen patients had a five-year disease free survival (35.29%). Discussion Metastases localized in the II and III levels of the neck and in the upper two-thirds of the V level, should be primarily treated by neck dissection. Lymph nodes up to 3cm in diameter (N1) are operated by a modified radical neck dissection. Lymph nodes over 3cm (N2) and 6cm in diameter (N3) are operated by radical or extended radical neck dissection. Conclusion Primary surgery plus postoperative radiotherapy provide satisfactory results in therapy of metastatic squamous cell carcinomas of the neck with unknown primary.

scholarly journals The importance of flaps in reconstruction of locoregionally advanced lateral skull-base cancer defects: a tertiary otorhinolaryngology referral centre experience

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Domen Vozel ◽  
Peter Pukl ◽  
Ales Groselj ◽  
Aleksandar Anicin ◽  
Primoz Strojan ◽  
...  
Keyword(s):  
Skull Base ◽  
Neck Dissection ◽  
Temporal Bone ◽  
Free Flap ◽  
Radical Neck Dissection ◽  
Selective Neck Dissection ◽  
Flap Reconstruction ◽  
Referral Centre ◽  
Regional Flap ◽  
Lateral Skull Base

Abstract Background The aim of the study was to identify the value of extensive resection and reconstruction with flaps in the treatment of locoregionally advanced lateral skull-base cancer. Patients and methods The retrospective case review of patients with lateral skull-base cancer treated surgically with curative intent between 2011 and 2019 at a tertiary otorhinolaryngology referral centre was made. Results Twelve patients with locoregionally advanced cancer were analysed. Lateral temporal bone resection was performed in nine (75.0%), partial parotidectomy in six (50.0%), total parotidectomy in one (8.3%), ipsilateral selective neck dissection in eight (66.7%) and ipsilateral modified radical neck dissection in one patient (8.3%). The defect was reconstructed with anterolateral thigh free flap, radial forearm free flap or pectoralis major myocutaneous flap in two patients (17.0%) each. Mean overall survival was 3.1 years (SD = 2.5) and cancer-free survival rate 100%. At the data collection cut-off, 83% of analysed patients and 100% of patients with flap reconstruction were alive. Conclusions Favourable local control in lateral skull-base cancer, which mainly involves temporal bone is achieved with an extensive locoregional resection followed by free or regional flap reconstruction. Universal cancer registry should be considered in centres treating this rare disease to alleviate analysis and multicentric research.

scholarly journals Blindness after laryngectomy and bilateral neck dissection in a diabetic patient: case report

2001 ◽  
Vol 119 (5) ◽  
pp. 181-183 ◽  
Author(s):  
Rui Celso Martins Mamede ◽  
David Livingstone Alves Figueiredo ◽  
Fabrício Villela Mamede
Keyword(s):  
Case Report ◽  
Diabetic Patient ◽  
Neck Dissection ◽  
Total Laryngectomy ◽  
Malignant Tumors ◽  
Rare Complication ◽  
Radical Neck Dissection ◽  
Selective Neck Dissection ◽  
Intraoperative Hypotension ◽  
The Right

CONTEXT: Neck dissection that accompanies resection of the primary lesion in malignant tumors of the upper aerodigestive tracts may cause complications inherent to the procedure or to prolongation of surgical time, increasing the risks for the patient. Among the complications that might occur is blindness, a rare complication with only 10 cases reported in the literature thus far. OBJECTIVE: To present the case of a diabetic patient submitted to total laryngectomy and modified and selective neck dissection that resulted in blindness. CASE REPORT: The authors report on a patient submitted to total laryngectomy and selective neck dissection on the left side, and modified radical neck dissection on the right, who developed blindness. This was probably due to intraoperative hypotension plus the contribution of decompensated diabetes mellitus and thrombosis of the internal jugular vein on the right side. The possible causes, risk factors and care to be taken to prevent this rare but highly debilitating complication are discussed.

FRACTURE OF THE CLAVICLE FOLLOWING RADICAL NECK DISSECTION AND POSTOPERATIVE RADIOTHERAPY

1982 ◽  
Vol 92 (11) ◽  
pp. 1300???1307 ◽  
Author(s):  
Melvin Strauss ◽  
Michael J. Bushey ◽  
Chan Chung ◽  
Sheldon Baum
Keyword(s):  
Neck Dissection ◽  
Postoperative Radiotherapy ◽  
Radical Neck Dissection

scholarly journals Selective Neck Dissection and Survival in Pathologically Node-Positive Oral Squamous Cell Carcinoma

Cancers ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 269 ◽  
Author(s):  
Shunichi Shimura ◽  
Kazuhiro Ogi ◽  
Akihiro Miyazaki ◽  
Shota Shimizu ◽  
Takeshi Kaneko ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Radical Neck Dissection ◽  
Selective Neck Dissection ◽  
Neck Node ◽  
Node Positive

The most important prognostic factor in oral squamous cell carcinoma (OSCC) is neck metastasis, which is treated by neck dissection. Although selective neck dissection (SND) is a useful tool for clinically node-negative OSCC, its efficacy for neck node-positive OSCC has not been established. Sixty-eight OSCC patients with pN1–3 disease who were treated with curative surgery using SND and/or modified-radical/radical neck dissection (MRND/RND) were retrospectively reviewed. The neck control rate was 94% for pN1–3 patients who underwent SND. The five-year overall survival (OS) and disease-specific survival (DSS) in pN1-3 OSCC patients were 62% and 71%, respectively. The multivariate analysis of clinical and pathological variables identified the number of positive nodes as an independent predictor of SND outcome (OS, hazard ratio (HR) = 4.98, 95% confidence interval (CI): 1.48–16.72, p < 0.01; DSS, HR = 6.44, 95% CI: 1.76–23.50, p < 0.01). The results of this retrospective study showed that only SND for neck node-positive OSCC was appropriate for those with up to 2 lymph nodes that had a largest diameter ≤3 cm without extranodal extension (ENE) of the neck and adjuvant radiotherapy. However, the availability of postoperative therapeutic options for high-risk OSCC, including ENE and/or multiple positive lymph nodes, needs to be further investigated.

Sign in / Sign up

Export Citation Format

Share Document