Neurorehabilitation of alexia without agraphia - a case report

Introduction. Alexia without agraphia is an impairment of reading ability. Speech, auditory comprehension, repetition and writing are relatively intact. Due to a damage of the splenium of corpus callosum, alexia without agraphia is considered to be an interhemispheric disconnection syndrome. Case Report. We presented a 71-year-old male, with chronic hypertension, diabetes mellitus and dyslipidemia. The magnetic resonance imaging showed a lesion in the left medial temporal region, including the equilateral thalamus, posterior cingulate gyrus, splenium of corpus callosum, lingual occipital gyrus, and the tail of the hippocampus. Lacunar ischemia was found on the right side of cerebellum. The neuro-linguistic diagnostic protocol included the Mini Mental State Examination, Boston Diagnostic Aphasia Examination, Boston Naming Test and phonemic and category fluency tests. We have also designed a clinical protocol for color recognition assessment. The results showed a mild cognitive impairment related to the time and space orientation, delayed memory and reading. On the speech and language levels, a severe acquired alexia without agraphia was registered which was not associated with other language modalities. Conclusion. The neuro-linguistic tests and clinical techniques provide a rather reliable diagnostic criteria, which is the basis for neuro-rehabilitation. The rehabilitation protocol refers to training techniques: tactile-kinesthetic recognition of graphemes and application of various reading techniques, such as letter-by-letter reading, Multiple Oral Re-reading, melodic intonation therapy and oral reading technique in order to facilitate rehabilitation of reading.

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Callosal disconnection syndrome after ischemic stroke of the corpus callosum due to meningococcal meningitis: A case report

Journal of the Neurological Sciences ◽

10.1016/j.jns.2016.08.009 ◽

2016 ◽

Vol 369 ◽

pp. 119-120 ◽

Cited By ~ 3

Author(s):

Nicola A. Marchi ◽

Radek Ptak ◽

Corinne Wetzel ◽

Maria I. Vargas ◽

Armin Schnider ◽

...

Keyword(s):

Ischemic Stroke ◽

Case Report ◽

Corpus Callosum ◽

Meningococcal Meningitis ◽

Disconnection Syndrome

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Lissencephaly, abnormal genitalia and refractory epilepsy: case report of XLAG syndrome

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2006000600027 ◽

2006 ◽

Vol 64 (4) ◽

pp. 1023-1026 ◽

Cited By ~ 2

Author(s):

Mônica Jaques Spinosa ◽

Paulo Breno Noronha Liberalesso ◽

Simone Carreiro Vieira ◽

Alaídes Susana Fojo Olmos ◽

Alfredo Löhr Júnior

Keyword(s):

Case Report ◽

Corpus Callosum ◽

Refractory Epilepsy ◽

Genetic Disorder ◽

Ductus Arteriosus ◽

Ambiguous Genitalia ◽

Second Child ◽

Neonatal Onset ◽

The Right ◽

Male Genotype

INTRODUCTION: X-linked lissencephaly with ambiguous genitalia (XLAG) is a recently described genetic disorder caused by mutation in the aristaless-related homeobox (ARX) gene (Xp22.13). Patients present with lissencephaly, agenesis of the corpus callosum, refractory epilepsy of neonatal onset, acquired microcephaly and male genotype with ambiguous genitalia. CASE REPORT: Second child born to healthy nonconsanguineous parents, presented with seizures within the first hour of life that remained refractory to phenobarbital, phenytoin and midazolam. Examination identified microcephaly, axial hypotonia, pyramidal signs and ambiguous genitalia. EEG showed disorganized background activity and seizures starting at the right midtemporal, central and occipital regions. MRI showed diffuse pachygyria, moderate thickening of the cortex, enlarged ventricles, agenesis of the corpus callosum and septum pellucidum. Karyotype showed a 46,XY genotype. Additional findings were hypercalciuria, vesicoureteral reflux, patent ductus arteriosus and chronic diarrhea.

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Pushing behavior and hemiparesis: which is critical for functional recovery in pusher patients ? Case report

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2007000300035 ◽

2007 ◽

Vol 65 (2b) ◽

pp. 536-539 ◽

Cited By ~ 9

Author(s):

Taiza E.G. Santos-Pontelli ◽

Octávio M. Pontes-Neto ◽

José Fernando Colafêmina ◽

Dráulio B. de Araújo ◽

Antônio Carlos Santos ◽

...

Keyword(s):

Case Report ◽

Barthel Index ◽

Functional Improvement ◽

Chronic Hypertension ◽

Acute Hemorrhage ◽

Lateral Posterior ◽

History Of ◽

Lateral Posterior Nucleus ◽

Neuroimaging Study ◽

The Right

We report a sequential neuroimaging study in a 48-years-old man with a history of chronic hypertension and lacunar strokes involving the ventral lateral posterior nucleus of the thalamus. The patient developed mild hemiparesis and severe contraversive pushing behavior after an acute hemorrhage affecting the right thalamus. Following standard motor physiotherapy, the pusher behavior completely resolved 3 months after the onset and, at that time, he had a Barthel Index of 85, although mild left hemiparesis was still present. This case report illustrates that pushing behavior itself may be severely incapacitating, may occur with only mild hemiparesis and affected patients may have dramatic functional improvement (Barthel Index 0 to 85) after resolution pushing behavior without recovery of hemiparesis.

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Intracranial Hemorrhage in the Corpus Callosum Presenting as Callosal Disconnection Syndrome: FDG-PET and Tractography: A Case Report

Annals of Rehabilitation Medicine ◽

10.5535/arm.2014.38.6.871 ◽

2014 ◽

Vol 38 (6) ◽

pp. 871 ◽

Cited By ~ 5

Author(s):

In Hwan Kim ◽

Soyoung Lee ◽

Chang-Young Lee ◽

Dong Gyu Lee

Keyword(s):

Case Report ◽

Corpus Callosum ◽

Intracranial Hemorrhage ◽

Fdg Pet ◽

Disconnection Syndrome

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065 Obstructive hydrocephalus presenting primarily as a corpus callosum disconnection syndrome: a case report

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp-2011-301993.107 ◽

2012 ◽

Vol 83 (3) ◽

pp. e1.10-e1

Author(s):

I Imam ◽

J Palmer

Keyword(s):

Case Report ◽

Corpus Callosum ◽

Obstructive Hydrocephalus ◽

Disconnection Syndrome

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Case Report: Corpus callosal apraxia following acute ischemic stroke

F1000Research ◽

10.12688/f1000research.15059.1 ◽

2018 ◽

Vol 7 ◽

pp. 731

Author(s):

Santhosh Narayanan ◽

Gomathy Subramaniam

Keyword(s):

Computed Tomography ◽

Ischemic Stroke ◽

Case Report ◽

Corpus Callosum ◽

The Body ◽

Cerebral Hemispheres ◽

Diagnostic Challenge ◽

Compact Structure ◽

Ischemic Infarct ◽

The Right

The corpus callosum is a compact structure that connects the right and left cerebral hemispheres. Here we report the case of a 50 year old woman who presented with features of corpus callosum apraxia, initially mistaken as psychiatric symptom by her relatives. Computed tomography and magnetic resonance of brain confirmed the diagnosis of acute ischemic infarct in the body of the corpus callosum. Isolated stroke involving the corpus callosum is rarely reported in literature and is a diagnostic challenge due to atypical clinical features.

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: Different clinical features in a family – A case report

Medicinski pregled ◽

10.2298/mpns1912375r ◽

2019 ◽

Vol 72 (11-12) ◽

pp. 375-378

Author(s):

Svetlana Ruzicka-Kaloci ◽

Marija Stamenkovic ◽

Zeljko Zivanovic ◽

Aleksandar Jovanovic ◽

Tamara Rabi-Zikic ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Case Report ◽

Magnetic Resonance ◽

Corpus Callosum ◽

Neurological Examination ◽

Autosomal Dominant ◽

Monogenic Disease ◽

Resonance Imaging ◽

Causal Therapy ◽

The Right

Introduction. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy is the most common monogenic disease of small blood vessels. It commonly presents with repeated epi?sodes of brain ischemia leading to progressive subcortical vascular dementia, migraine attacks and mood disorders. Case Report. A 46-year-old male patient was admitted with clinical presentation of stroke. The neurological examination revealed mild divergent strabismus and a left homonymous hemianopia. Brain magnetic resonance imaging showed subacute infarction in the region of the posterior cerebral artery to the right, as well as similar lesions in the splenium of the corpus callosum, numerous mostly confluent and some discrete T2-weighted/fluid attenuated inversion recovery hyperintense lesions of the centrum semiovale, corona radiata, frontoparietal subcortex, capsula externa, periventricularly at the level of occipital and temporal horns of lateral chambers bilaterally, and small punctiform lesions in the region of the corpus callosum. The magnetic resonance angiography findings were normal. The patient?s brother underwent neurological examination at the age of 42 due to severe headaches, double vision, confusion, and numbness in the right arm. The magnetic resonance imaging of the endocranium showed multifocal confluent ischemic lesions predominantly in the frontal and temporal lobes, as well as focal microangiopathic changes in the gangliocapsular regions bilaterally in the brainstem and cerebellum. In agreement with the patient and his brother, genetic analyses were performed in both of them, and a mutation in exon 3 of the neurogenic locus notch homolog protein 3 gene was confirmed (c.505C > t, p.R169C). Conclusion. Although there is no causal therapy, it is very important to diagnose cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in order to implement measures to prevent cerebrovascular diseases in both patients and their family members.

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Unusual presentation of ciliary body melanoma - a case report

Health Renaissance ◽

10.3126/hren.v11i3.9657 ◽

2014 ◽

Vol 11 (3) ◽

pp. 287-289

Author(s):

T Sarbajna ◽

P Lavaju ◽

M Agarwal ◽

K Ahmad

Keyword(s):

Case Report ◽

Lacrimal Gland ◽

Ciliary Body ◽

Histopathological Examination ◽

Temporal Region ◽

Direct Extension ◽

Tender Mass ◽

Temporal Quadrant ◽

The Right ◽

Ciliary Body Melanoma

Background: Ciliary body melanoma rarely grows transclerally by direct extension and can metastasize locally into the orbit or conjunctiva. Objective: To report a case of ciliary body melanoma presenting clinically as a mass in the lacrimal gland region. Case: A 40-year-old female presented to the ophthalmic out-patient department with the complaint of a swelling in the right upper and outer lid region for 4 years. Ocular examination revealed a phthisical right eye. A firm, non-tender mass was palpable in the temporal quadrant of the right supraorbital region. Ultrasonography showed retinal detachment of the right eye. The CT-scan of the orbit was reportedly suggestive of a right lacrimal gland mass. Superolateral transperiosteal orbitotomy was planned for excision of the lacrimal gland mass. Intraoperatively, a well defined mass arising from the supero-temporal region of the right globe was noticed. The procedure was converted to enucleation of the right eye. Histopathological examination of the mass showed features of ciliary body melanoma. Conclusion: Extrascleral extension of ciliary body melanoma can present as a mass in the lacrimal gland region. DOI: http://dx.doi.org/10.3126/hren.v11i3.9657 Health Renaissance 2013;11(3):287-289

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Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽

10.1024/0301-1526/a000101 ◽

2011 ◽

Vol 40 (3) ◽

pp. 251-255 ◽

Cited By ~ 4

Author(s):

Gruber-Szydlo ◽

Poreba ◽

Belowska-Bien ◽

Derkacz ◽

Badowski ◽

...

Keyword(s):

Case Report ◽

Magnetic Resonance Angiography ◽

Popliteal Artery ◽

Doppler Ultrasonography ◽

Histopathological Examination ◽

Previous History ◽

Plain Radiography ◽

Artery Thrombosis ◽

History Of ◽

The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

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