Reporting Errors Inflate Third-Trimester Abortion Rate in Georgia; True Rate is Four per 100,000

1983 ◽  
Vol 15 (4) ◽  
pp. 196
QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Ashraf Mohamed Farouk Kortam ◽  
Tarek Aly Raafat ◽  
Rehab Mohamed Abd El Rahman ◽  
Amir Hamdy Abd El Hady Mahfouz

Abstract Background Abortion is the termination of pregnancy by any means (surgical or medical) before the age of viability. The definition varies in duration of gestational age according to the countries and available facilities. Estrogen is important in the maintenance of pregnancy. Aromatase inhibitors such as letrozole, suppress the peripheral conversion of androgen to estrogen, the use of letrozole combined with vaginal misoprostol was more effective than misoprostol alone in termination of pregnancy. Objective Assessing the efficacy of addition of letrozole to Misoprostol in medically induced abortion in the second trimester of pregnancy in the Maternity hospital of Ain Shams University. Methods This clinical trial was conducted at Ain Shams University Maternity hospital in the period between December 2018 and May 2019. Patients that seem to be fulfilling the inclusion criteria were recruited, then informed written consent was taken from every patient before starting the examination That was followed by detailed history and examination of all patients to confirm fulfilling the inclusion and exclusion criteria. Results This study demonstrated that 10 mg letrozole for three days followed by 800 mcg of vaginal misoprostol is more effective than misoprostol alone for second trimester abortion. In the total of 72 women were recruited the complete abortion rate of the letrozole group was significantly higher than that of the control group (61,1% in the letrozole group compared with 33,3% in the control group). Conclusion s: The use of letrozole in addition to misoprostol was associated with a higher complete abortion rate, shorter induction to abortion interval and shorter curettage rates compared to a placebo followed by misoprostol in patients undergoing induction of abortion between 12 & 24 weeks gestation.


2012 ◽  
Vol 8 (3) ◽  
pp. 321-324
Author(s):  
S R Tamrakur ◽  
C D Chawla

Background Cervical incompetence is one of the main contributors to repeated pregnancy loss, accounting for approximately 25% of the cases. Typically it results in progressive cervical dilatation, leading to a painless second- or early-third-trimester abortion. Objectives The main objective of the study was to explore the benefit from cervical cerclage in pregnant women with anatomical cervical incompetence Methods In a review of the operation and labour registers from January 2006 till January 2010, a total of 38 cervical cerclage procedures were performed at Dhulikhel Hospital (DH). In the study caste, parity, gestational age, diagnostic criteria, postoperative complications and pregnancy outcomes of the cases were analyzed. Results Two of the 38 cases didn’t come for delivery at Dhulikhel Hospital (Kathmandu University Teaching Hospital). Four women haven’t delivered at the time of data analysis. So pregnancy outcomes were analyzed among 32 cases while rests of the variables were analyzed among 38 cases. Of them 18 cases (47%) were Brahmin, 22 cases (58%) were between 20-25 years old and 32 cases (84%) were from Kavre district.  All cases were booked cases (they had antenatal care in the hospital) and 14 patients (37%) were third gravida. Most cases had 2 to 4 antenatal visits prior to suturing. Two cases were diagnosed with a bicornuate uterus. 21 cases (55%) had a previous history of at least one dilatation and evacuation.  33 cases (87%) were diagnosed with cervical incompetence clinically and confirmed by ultrasound. The remaining 13% were assessed, in the absence of a history of mid-trimester abortion, of having a high suspicion of cervical incompetence after mid-trimester scan with measurement of cervical length. In 18 cases (47%), cervical cerclage were done at 15 to 20 weeks of gestation. The postoperative period was uneventful in all 38 cases.  All cases (32) delivered in DH were assisted by consultant obstetricians. 19 out 32 cases (59%) were delivered vaginally at term. Conclusions38 cases were included in the study. Pregnancy outcomes were analyzed among 32 cases while rests of the variables were analyzed among 38 cases. 31 out 32 cases were delivered with good foetal weight. It clearly shows pregnant women with anatomical cervical incompetence were benefitted from cervical cerclage. The authors recommend an early trans vaginal scan in any patient with a history of mid trimester abortion or preterm labour. The cervical cerclage procedure therefore should be available more widely to benefit those patients with proven or strongly suspected cervical incompetence.DOI: http://dx.doi.org/10.3126/kumj.v8i3.6222 Kathmandu Univ Med J 2010;8(3):321-24 


1986 ◽  
Vol 18 (2) ◽  
pp. 109-112 ◽  
Author(s):  
A. M. Das ◽  
V. L. Paranjape ◽  
S. Winblad

2009 ◽  
Vol 29 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Oshri Barel ◽  
Zvi Vaknin ◽  
Noam Smorgick ◽  
Orit Reish ◽  
Sonia Mendlovic ◽  
...  

Bioethics ◽  
1999 ◽  
Vol 13 (3-4) ◽  
pp. 306-313 ◽  
Author(s):  
Sjef Gevers

Author(s):  
Frank A. Chervenak ◽  
Laurence B. McCullough ◽  
Stuart Campbell

2021 ◽  
pp. 1-3
Author(s):  
Karuna Kanta Das ◽  
Bijoy Kumar Dutta ◽  
Chintumoni Gogoi

Objective- To compare the relative efficacy and success rate of combination of mifepristone and misoprostol with misoprostol alone in mid-trimester abortion by correlating induction abortion interval (IAI) between two study groups. Methods- A comparative study was carried out by dividing 100 women seeking for abortion into two groups (50 each). GroupA received 200mg mifepristone orally followed by 600mcg misoprostol vaginally (24 hours later) which was repeated 4 hourly by 400mcg sublingual misoprostol upto a maximum of 5 doses. GroupB received 600mcg misoprostol vaginally and dose was repeated 4 hourly by 400mcg of misoprostol sublingually. Result- the success rate in GroupA was 100%, whereas in Group B was 94%. The mean IAI in GroupA was lesser (10.8 hours) as compared to GroupB (13.5 hours) p value 0.01. The mean dose of misoprostol in GroupA was 1400mcg compared to GroupB 1760mcg (p value 0.0001). Conclusion- Pre-treatment with mifepristone significantly shortens the IAI and increase the successful abortion rate.


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