Nevus Spilus with Synchronous Melanomas: Case Report and Literature Review

2009 ◽  
Vol 13 (2) ◽  
pp. 96-101 ◽  
Author(s):  
Ari-Nareg Meguerditchian ◽  
Richard T. Cheney ◽  
John M. Kane

Background: Nevus spilus is a rare, acquired, and often large cutaneous lesion consisting of a light brown background macule containing varying numbers of small darker macular or papular areas. Objective: Nevus spilus may contain dysplastic melanocytic elements, and there are also reports of melanoma arising from nevus spilus. However, the absolute risk for malignant transformation is not well defined. Conclusion: We discuss a case of synchronous melanomas arising from a nevus spilus and potential management recommendations based on a review of the pertinent literature.

2017 ◽  
Vol 36 ◽  
pp. 34-37 ◽  
Author(s):  
Ibrahim AlAwadh ◽  
Turki Aldrees ◽  
Saleh AlQaryan ◽  
Sami Alharethy ◽  
Hassan AlShehri

2019 ◽  
Vol 2 ◽  
pp. 100006 ◽  
Author(s):  
Ronie Romelean Jayapalan ◽  
Kein Seong Mun ◽  
Kum Thong Wong ◽  
Sheau Fung Sia

2008 ◽  
Vol 88 (1) ◽  
pp. 43-46 ◽  
Author(s):  
KH Lee ◽  
JE Kim ◽  
BK Cho ◽  
YC Kim ◽  
CJ Park

2009 ◽  
Vol 124 (1) ◽  
pp. 101-104 ◽  
Author(s):  
V Visvanathan ◽  
H Wallace ◽  
P Chumas ◽  
Z G G Makura

AbstractObjective:Inverted papilloma is a rare but locally aggressive tumour with the potential for malignant transformation. Intracranial extension or complications secondary to inverted papilloma are extremely rare. We report a case of inverted papilloma with a large frontal sinus mucocele eroding the frontal sinus, which presented with sudden neurological compromise. A literature review on intracranial extension of such tumours is also included.Methods:A Medline search of articles, using the terms ‘inverted papilloma’, ‘Ringertz tumour’, ‘intracranial extension’ and ‘complication’. Suitable references from the collected articles were also reviewed. Articles published in English were selected and reviewed.Results:A total of 10 cases was identified. Intracranial spread was more commonly seen in recurrent cases, especially if the recurrence involved the cribriform plate, fovea ethmoidalis or orbits. Cases with extradural disease seemed to have a better prognosis than those with intradural spread.Conclusions:Intracranial involvement of inverted papilloma is extremely rare, and is usually seen in recurrent cases. This case report highlights an unusual but serious case of inverted papilloma presenting with acute neurological deterioration secondary to a large frontal sinus mucocele eroding the frontal sinus. A literature review on intracranial extension of inverted papilloma indicated that common sites of intracranial spread include the cribriform plate, fovea ethmoidalis and orbits. The prognosis for patients with such tumours depends on the type of dural involvement, with intradural extension carrying a poorer prognosis.


Neurosurgery ◽  
1991 ◽  
Vol 28 (4) ◽  
pp. 588-592 ◽  
Author(s):  
Anil Nanda ◽  
Leonard F. Hirsh ◽  
Kristina Antoiniades

Abstract Malignant transformation in a recurrent chordoma in the thoracic region is extremely uncommon. One new case, as well as a review of spinal chordomas that have undergone malignant transformation, is reported. Such cases emphasize the importance of the aggressive initial surgical treatment of spinal tumors.


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